Cheap flights from CLE to STL (Hopkins Intl. to Lambert-St. Louis Intl.)

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Cheap Flights from CLE to STL starting at $50 One Way, $131 Round Trip

Prices starting at $131 for return flights and $50 for one-way flights to Lambert-St. Louis Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Apr 10 - Tue, Apr 14
CLE
Cleveland
STL
St. Louis
$131 Roundtrip, found 5 days ago
$131
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Apr 10 from Cleveland to St. Louis, returning Tue, Apr 14, priced at $131 found 5 days ago
Fri, Apr 10 - Tue, Apr 14
CLE
Cleveland
STL
St. Louis
$136 Roundtrip, found 5 days ago
$136
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Apr 10 from Cleveland to St. Louis, returning Tue, Apr 14, priced at $136 found 5 days ago
Sat, Apr 25 - Tue, Apr 28
CLE
Cleveland
STL
St. Louis
$138 Roundtrip, found 1 day ago
$138
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Apr 25 from Cleveland to St. Louis, returning Tue, Apr 28, priced at $138 found 1 day ago
Sat, Apr 25 - Tue, Apr 28
CLE
Cleveland
STL
St. Louis
$141 Roundtrip, found 1 day ago
$141
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Apr 25 from Cleveland to St. Louis, returning Tue, Apr 28, priced at $141 found 1 day ago
Wed, May 13 - Sat, May 16
CLE
Cleveland
STL
St. Louis
$144 Roundtrip, found 3 days ago
$144
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, May 13 from Cleveland to St. Louis, returning Sat, May 16, priced at $144 found 3 days ago

Hotel Ideas near Lambert-St. Louis Intl.

Airport Hotels near Lambert-St. Louis Intl.

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Mar 22 to Mar 23
$106 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,860 reviews)
Clean, comfortable, safe place directly across the highway at airport. Very nice staff.

Reviewed on Mar 13, 2026

Pear Tree Inn St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$139 nightly
The price is $165 total per night from Mar 22 to Mar 23
$165 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,001 reviews)
Right across the street from the airport

Reviewed on Mar 13, 2026

Hilton St. Louis Airport
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 out of 5
10820 Pear Tree Lane St. Ann MO
$102 nightly
The price is $120 total per night from Mar 22 to Mar 23
$120 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,540 reviews)
Refrigerator barely cold and upgrades needed. Staff tried to help, but no maintenance on site

Reviewed on Mar 12, 2026

Wingate by Wyndham St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In St. Louis

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$106 nightly
The price is $124 total per night from Mar 18 to Mar 19
$124 total
Mar 18 - Mar 19
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,868 reviews)
Great location, minutes from every downtown St Louis attraction. Perfect for weekend getaways for couples or families. Happy hour was a plus!

Reviewed on Mar 13, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$99 nightly
The price is $116 total per night from Mar 22 to Mar 23
$116 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,106 reviews)
Hotel no hot water and is going thru renov

Reviewed on Mar 13, 2026

Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$135 nightly
The price is $158 total per night from Mar 18 to Mar 19
$158 total
Mar 18 - Mar 19
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,347 reviews)
Clean room good view.

Reviewed on Mar 13, 2026

Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Hotels With Airport Transportation

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$64 nightly
The price is $75 total per night from Apr 5 to Apr 6
$75 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,007 reviews)
Served its purpose as a cheap place to stay but it is severely run down. Literally chucks of wall and outlets missing and broken. Carpet coming up and gross. Phone didn’t work, shower head water pressure was very low and water took forever to get hot. Walls very thin and guests were loud. No microwave ...

Reviewed on Mar 12, 2026

Quality Inn Saint Louis Airport
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
$145 nightly
The price is $173 total per night from Apr 3 to Apr 4
$173 total
Apr 3 - Apr 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8/10 Very Good! (1,001 reviews)
The toilet had a leak and even though it said it was a 4 star, other than the bar, i only saw three stars

Reviewed on Feb 21, 2026

Marriott St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$139 nightly
The price is $165 total per night from Mar 22 to Mar 23
$165 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,001 reviews)
Right across the street from the airport

Reviewed on Mar 13, 2026

Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced St. Louis Hotels

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$64 nightly
The price is $75 total per night from Apr 5 to Apr 6
$75 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,007 reviews)
Served its purpose as a cheap place to stay but it is severely run down. Literally chucks of wall and outlets missing and broken. Carpet coming up and gross. Phone didn’t work, shower head water pressure was very low and water took forever to get hot. Walls very thin and guests were loud. No microwave ...

Reviewed on Mar 12, 2026

Quality Inn Saint Louis Airport
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard St. Louis MO
$79 nightly
The price is $92 total per night from Apr 6 to Apr 7
$92 total
Apr 6 - Apr 7
Total with taxes and fees
Stay at this motel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Gateway Arch and Busch Stadium are located ...
5.6/10 (833 reviews)
Bed had bugs and animal feces. Door did not lock, the room reeked of smoke. The floor was dirty and there was cigarette burns in the mattress. No smoke detector

Reviewed on Mar 9, 2026

Americas Best Value Inn St. Louis Downtown
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
6.6/10 (1,000 reviews)
Definitely an older hotel. Overall the room was kinda dingy.

Reviewed on Apr 11, 2024

Get rates
OYO Hotel St. Louis Downtown City Center MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in St. Louis

Days Inn by Wyndham St. Louis Lindbergh Boulevard

Days Inn by Wyndham St. Louis Lindbergh Boulevard

2.5 out of 5
South Lindbergh Boulevard, 3660 St. Louis MO
Book a stay at this family-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a nightclub. Popular attractions Laumeier Sculpture Park and Magic ...

Families like: Indoor pool, playground, game room, cribs

Get rates
Days Inn by Wyndham St. Louis Lindbergh Boulevard
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$135 nightly
The price is $158 total per night from Mar 18 to Mar 19
$158 total
Mar 18 - Mar 19
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,347 reviews)
Clean room good view.

Reviewed on Mar 13, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$106 nightly
The price is $124 total per night from Mar 18 to Mar 19
$124 total
Mar 18 - Mar 19
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,868 reviews)
Great location, minutes from every downtown St Louis attraction. Perfect for weekend getaways for couples or families. Happy hour was a plus!

Reviewed on Mar 13, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CLE to STL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
CLE Address & GPS
Address:
5300 Riverside Drive
Cleveland OH, 44135-3193
United States
IATA Code:
CLE
Longitude:
-81.83821
Latitude:
41.410856
Time Zone:
America/New_York
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from Cleveland Hopkins Intl. Airport to St. Louis Lambert International Airport?
We're delighted to inform you that Southwest Airlines will fly you directly from Cleveland to St. Louis. Book your seat on the plane now and enjoy a hassle-free, nonstop flight.
What is the shortest flight from CLE to St. Louis Lambert International Airport?
Jetting from Cleveland Hopkins Intl. Airport to Lambert Field will take a minimum of 5 hours and 15 minutes. Enjoy a beverage and get stuck into that book — here's your chance to sit back and relax.
How many hours flight from CLE to STL?
It takes just 5 hours and 21 minutes on average to travel from CLE to St. Louis Lambert International Airport. Pull out your travel book and start marking all the special places you want to visit. It won't be long before you'll be seeing them in person.
What airlines have the most flights from CLE to St. Louis Lambert International Airport?
Advertising 65 monthly flights between Cleveland and St. Louis, Southwest Airlines will get you there comfortably and safely.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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