Cheap flights from CLE to STL (Hopkins Intl. to Lambert-St. Louis Intl.)

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Cheap Flights from CLE to STL starting at $71 One Way, $138 Round Trip

Prices starting at $138 for return flights and $71 for one-way flights to Lambert-St. Louis Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Feb 27 - Mon, Mar 2
CLE
Cleveland
STL
St. Louis
$138 Roundtrip, found 7 hours ago
$138
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Fri, Feb 27 from Cleveland to St. Louis, returning Mon, Mar 2, priced at $138 found 7 hours ago
Thu, Jan 22 - Mon, Jan 26
CLE
Cleveland
STL
St. Louis
$141 Roundtrip, found 15 hours ago
$141
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Thu, Jan 22 from Cleveland to St. Louis, returning Mon, Jan 26, priced at $141 found 15 hours ago
Sat, Feb 21 - Mon, Feb 23
CLE
Cleveland
STL
St. Louis
$141 Roundtrip, found 7 hours ago
$141
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Sat, Feb 21 from Cleveland to St. Louis, returning Mon, Feb 23, priced at $141 found 7 hours ago
Fri, Feb 27 - Wed, Mar 4
CLE
Cleveland
STL
St. Louis
$155 Roundtrip, found 7 hours ago
$155
Roundtrip
found 7 hours ago
Select Frontier Airlines flight, departing Fri, Feb 27 from Cleveland to St. Louis, returning Wed, Mar 4, priced at $155 found 7 hours ago
Thu, Jan 22 - Wed, Jan 28
CLE
Cleveland
STL
St. Louis
$158 Roundtrip, found 8 hours ago
$158
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Thu, Jan 22 from Cleveland to St. Louis, returning Wed, Jan 28, priced at $158 found 8 hours ago

Hotel Ideas near Lambert-St. Louis Intl.

Airport Hotels near Lambert-St. Louis Intl.

Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$93 nightly
The price is $112 total per night from Dec 21 to Dec 22
$112 total
Dec 21 - Dec 22
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.4/10 Good! (1,001 reviews)
Tesla charger does not agrr

Reviewed on Dec 3, 2025

Hilton St. Louis Airport
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Dec 14 to Dec 15
$106 total
Dec 14 - Dec 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,754 reviews)
Perfect

Reviewed on Dec 7, 2025

Pear Tree Inn St. Louis Airport
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 out of 5
10820 Pear Tree Lane St. Ann MO
$108 nightly
The price is $127 total per night from Dec 14 to Dec 15
$127 total
Dec 14 - Dec 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,490 reviews)
Great location! Snow apocalypse hit, traffic stopped, I got on my phone and grabbed a room for the night! Hotel is clean, beds comfy, staff friendly and great bbq next door!

Reviewed on Dec 3, 2025

Wingate by Wyndham St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In St. Louis

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$89 nightly
The price is $105 total per night from Dec 23 to Dec 24
$105 total
Dec 23 - Dec 24
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (4,015 reviews)
The elevators were acting up and it was kinda an inconvenience

Reviewed on Dec 9, 2025

Hyatt Regency St. Louis at The Arch
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
$93 nightly
The price is $111 total per night from Dec 25 to Dec 26
$111 total
Dec 25 - Dec 26
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,142 reviews)
The staff was great !!!

Reviewed on Dec 7, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
$95 nightly
The price is $111 total per night from Dec 16 to Dec 17
$111 total
Dec 16 - Dec 17
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,163 reviews)
The room was clean and the staff were extremely friendly and personable!

Reviewed on Dec 9, 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Hotels With Airport Transportation

Quality Inn St. Louis Airport Hotel

Quality Inn St. Louis Airport Hotel

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$57 nightly
The price is $66 total per night from Jan 4 to Jan 5
$66 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6/10 (1,000 reviews)
Cleane saff friendly nice

Reviewed on Nov 17, 2025

Quality Inn St. Louis Airport Hotel
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
$128 nightly
The price is $152 total per night from Dec 19 to Dec 20
$152 total
Dec 19 - Dec 20
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
7.8/10 Good! (1,002 reviews)
Room was good, however the heating would not shut off and it was extremely hot. Maintenance came up and tried to fix and gave us a box fan.

Reviewed on Dec 6, 2025

Marriott St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$93 nightly
The price is $112 total per night from Dec 21 to Dec 22
$112 total
Dec 21 - Dec 22
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.4/10 Good! (1,001 reviews)
Tesla charger does not agrr

Reviewed on Dec 3, 2025

Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced St. Louis Hotels

Quality Inn St. Louis Airport Hotel

Quality Inn St. Louis Airport Hotel

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$57 nightly
The price is $66 total per night from Jan 4 to Jan 5
$66 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6/10 (1,000 reviews)
Cleane saff friendly nice

Reviewed on Nov 17, 2025

Quality Inn St. Louis Airport Hotel
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard St. Louis MO
$79 nightly
The price is $92 total per night from Dec 15 to Dec 16
$92 total
Dec 15 - Dec 16
Total with taxes and fees
Stay at this motel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Gateway Arch and St. Louis Union Station are located ...
5.6/10 (818 reviews)
We needed a place near the convention center that wasn't crazy expensive. The worker and manager were both very friendly.

Reviewed on Dec 9, 2025

Americas Best Value Inn St. Louis Downtown
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Definitely an older hotel. Overall the room was kinda dingy.

Reviewed on Apr 11, 2024

Get rates
OYO Hotel St. Louis Downtown City Center MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in St. Louis

Days Inn by Wyndham St. Louis Lindbergh Boulevard

Days Inn by Wyndham St. Louis Lindbergh Boulevard

2.5 out of 5
South Lindbergh Boulevard, 3660 St. Louis MO
Book a stay at this family-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a nightclub. Popular attractions Laumeier Sculpture Park and Magic ...
6.6/10 (1,000 reviews)

Families like: Indoor pool, playground, game room, cribs

Travelers say...
The Pool, and things for the kids to do was great.

Reviewed on Feb 18, 2021

Get rates
Days Inn by Wyndham St. Louis Lindbergh Boulevard
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$128 nightly
The price is $150 total per night from Dec 15 to Dec 16
$150 total
Dec 15 - Dec 16
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,275 reviews)
Great staff , Tim was funny and fun to chat with. The breakfast and dinner were more than we expected. You even get 3 adult drinks

Reviewed on Dec 8, 2025

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$94 nightly
The price is $110 total per night from Dec 14 to Dec 15
$110 total
Dec 14 - Dec 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,744 reviews)
The parking lot was congested. Had to park in parking garage that was a little inconvenient but worked for the day we stayed. We were there for an event which was within walking distance if you're able.

Reviewed on Dec 5, 2025

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CLE to STL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
CLE Address & GPS
Address:
5300 Riverside Drive
Cleveland OH, 44135-3193
United States
IATA Code:
CLE
Longitude:
-81.83821
Latitude:
41.410856
Time Zone:
America/New_York
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from Cleveland Hopkins Intl. Airport to St. Louis Lambert International Airport?
We're delighted to inform you that Southwest Airlines will fly you directly from Cleveland to St. Louis. Book your seat on the plane now and enjoy a hassle-free, nonstop flight.
What is the shortest flight from CLE to St. Louis Lambert International Airport?
Jetting from Cleveland Hopkins Intl. Airport to Lambert Field will take a minimum of 5 hours and 15 minutes. Enjoy a beverage and get stuck into that book — here's your chance to sit back and relax.
How many hours flight from CLE to STL?
It takes just 5 hours and 21 minutes on average to travel from CLE to St. Louis Lambert International Airport. Pull out your travel book and start marking all the special places you want to visit. It won't be long before you'll be seeing them in person.
What airlines have the most flights from CLE to St. Louis Lambert International Airport?
Advertising 65 monthly flights between Cleveland and St. Louis, Southwest Airlines will get you there comfortably and safely.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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