
$97 Cheap flight deals from Houston (HOU) to Northeast Missouri (STL)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Houston to Northeast Missouri
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $97 One Way, $190 Round Trip from Houston to Northeast Missouri
Prices starting at $190 for return flights and $97 for one-way flights to Northeast Missouri were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Northeast Missouri economy flight packages

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Jul 3 - Jul 5
Houston (HOU) to St. Louis (STL)
Reviewed on May 12, 2026

The Wildwood Hotel
Jul 3 - Jul 5
Houston (HOU) to St. Louis (STL)
Reviewed on Feb 24, 2026

More About Flying To Northeast Missouri from Houston
Route Information for Flights from Houston to Northeast Missouri
Origin Airport IATA Code | HOU |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Houston to Northeast Missouri
If you are looking to find the best deals on Houston to Northeast Missouri flights, look no further than Orbitz. Orbitz offers guaranteed low prices as well as cutting-edge mobile tools to help you book cheap flights from Houston to Northeast Missouri.
Mobile Apps Make Life Easier
Our mobile apps for Android and iPhone phones as well as tablets and iPads let you find the cheapest flights from Houston to Northeast Missouri—whether you are at home or running errands. Use the apps to also keep track of delays to your Houston to Northeast Missouri flights and baggage claim information.
Get Miles for Your Flights From Houston to Northeast Missouri
It’s easy to earn points or miles for your frequent flyer or airline loyalty program on qualifying Houston to Northeast Missouri flights with Orbitz. You can add your frequent flyer number to your online flight booking, and even store your numbers in your Orbitz account profile so they automatically get added the next time you book a flight.
Stay Informed While You Travel
Orbitz keeps you updated on information that’s relevant to your flights from Houston to Northeast Missouri. We can send you and six of your personal contacts free travel alerts via SMS text, voicemail, or email, so you instantly know about flight delays or changes.
Keep More Money in Your Pocket With Discount Flights
Orbitz looks for the best deals on Houston to Northeast Missouri flights for you. Mix and match airlines for your departing and return flights to fit your travel schedule and budget.
Flights from Houston
- Houston to New York
- Houston to Chicago
- Houston to Orlando
- Houston to Los Angeles
- Houston to Dallas
- Houston to New Orleans
- Houston to Toronto
- Houston to London
- Houston to Phoenix
- Houston to Washington
- Houston to Detroit
- Houston to Paris
- Houston to Rome
- Houston to San Francisco
- Houston to Indianapolis
- Houston to Kansas City
- Houston to Hartford
- Houston to Montreal
- Houston to Edmonton
- Houston to Shanghai
More Destinations
- Flights from Duluth to Canton
- Flights from Alexandria to Canton
- Flights from Flint to Canton
- Flights from Austin to Canton
- Flights from Chicago to Canton
- Flights from Houston to Canton
- Flights from Indianapolis to Canton
- Flights from Las Vegas to Canton
- Flights from Lima to Canton
- Flights from Los Angeles to Canton
- Flights from Montreal to Canton
- Flights from New York to Canton
- Flights from Phoenix to Canton
- Flights from Raleigh to Canton
- Flights from Salt Lake City to Canton
- Flights from Charleston to Canton
- Flights from Accra to Canton
- Flights from Fort Lauderdale to Canton
- Flights from Tulsa to Canton
- Flights from Shreveport to Canton
- Flights from Allentown to Canton
- Flights from Huntsville to Canton
- Flights from Fresno to Canton
- Flights from Bend to Canton
- Flights from Wenatchee to Macon
- Flights from Chicago to Macon
- Flights from Nashville to Macon
- Flights from Pittsburgh to Macon
- Flights from Birmingham to Macon
- Flights from Tampa to Macon
- Flights from Biloxi to Macon
- Flights from Chihuahua to Macon
- Flights from Augusta (AGS) to Kirksville (IRK)
- Flights from Denver (APA) to Kirksville (IRK)
- Flights from Bradford (BFD) to Kirksville (IRK)
- Flights from Cheongju (CJJ) to Kirksville (IRK)
- Flights from Destin (DSI) to Kirksville (IRK)
- Flights from Diamantina (DTI) to Kirksville (IRK)
- Flights from Flint (FNT) to Kirksville (IRK)
- Flights from Greenville (GSP) to Kirksville (IRK)
- Flights from Halmstad (HAD) to Kirksville (IRK)
- Flights from Hoquiam (HQM) to Kirksville (IRK)
- Flights from Iloilo (ILO) to Kirksville (IRK)
- Flights from Lafayette (LAF) to Kirksville (IRK)
- Flights from Myrtle Beach (MYR) to Kirksville (IRK)
- Flights from Jacksonville (OAJ) to Kirksville (IRK)
- Flights from Ostrava (OSR) to Kirksville (IRK)
- Flights from Beijing (PEK) to Kirksville (IRK)
- Flights from Port Harcourt (PHC) to Kirksville (IRK)
- Flights from Peoria (PIA) to Kirksville (IRK)
- Flights from Pellston (PLN) to Kirksville (IRK)
- Flights from Rio Cuarto (RCU) to Kirksville (IRK)
- Flights from Rutland (RUT) to Kirksville (IRK)
- Flights from Moscow (SVO) to Kirksville (IRK)
- Flights from Vero Beach (VRB) to Kirksville (IRK)
- Flights from Esbjerg to Kirksville
- Flights from El Paso to Kirksville
- Flights from Longview to Kirksville
- Flights from Amsterdam to Kirksville
- Flights from Copenhagen to Kirksville
- Flights from Dublin to Kirksville
- Flights from Montreal to Kirksville
- Flights from Nashville to Kirksville
- Flights from Salt Lake City to Kirksville
- Flights from Vienna to Kirksville
- Flights from Cancun to Kirksville
- Flights from Liberal to Kirksville
- Flights from Manus Island to Kirksville
- Flights from Muskegon to Kirksville
- Flights from Mildura to Kirksville
- Flights from Pilot Point to Kirksville
- Flights from Suceava to Kirksville
- Flights from St. George to Kirksville
- Flights from Teller to Kirksville
- Flights from Waterloo to Kirksville
- Flights from Kamloops to Kirksville
- Flights from Myrtle Beach to Kirksville
- Flights from Oakland to Kirksville
- Flights from Nassau to Kirksville
- Flights from Santa Barbara to Kirksville
- Flights from Bentonville - Fayetteville to Kirksville
- Flights from Fort Myers to Kirksville
- Flights from Halifax to Kirksville
- Flights from Norfolk - Virginia Beach to Kirksville
- Flights from Mobile to Kirksville
- Flights from Tucson to Kirksville
- Flights from Asheville to Kirksville
- Flights from Tallahassee to Kirksville
- Flights from Riverton to Kirksville
- Flights from Concord to Kirksville
- Flights from Sioux Falls to Kirksville
- Flights from Lubbock to Kirksville
- Flights from Butte to Kirksville
- Flights from Fort Stockton to Kirksville
- Flights from Belize City to Kirksville
- Flights from Goleta to Kirksville
- Flights from Florence to Kirksville
- Flights from College Station to Kirksville
- Flights from San José del Cabo to Kirksville
- Flights from Richland to Kirksville
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
