Cheap flights from SAN to BUF (San Diego Intl. to Buffalo Niagara Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from SAN to BUF starting at $129 One Way, $264 Round Trip

Prices starting at $264 for return flights and $129 for one-way flights to Buffalo Niagara Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 1 - Tue, Sep 15
SAN
San Diego
BUF
Buffalo
$264 Roundtrip, found 5 days ago
$264
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Tue, Sep 1 from San Diego to Buffalo, returning Tue, Sep 15, priced at $264 found 5 days ago
Tue, Sep 1 - Tue, Sep 15
SAN
San Diego
BUF
Buffalo
$267 Roundtrip, found 5 days ago
$267
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Tue, Sep 1 from San Diego to Buffalo, returning Tue, Sep 15, priced at $267 found 5 days ago
Wed, Aug 26 - Wed, Sep 2
SAN
San Diego
BUF
Buffalo
$276 Roundtrip, found 3 days ago
$276
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Aug 26 from San Diego to Buffalo, returning Wed, Sep 2, priced at $276 found 3 days ago
Tue, Aug 18 - Tue, Aug 25
SAN
San Diego
BUF
Buffalo
$282 Roundtrip, found 3 days ago
$282
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Tue, Aug 18 from San Diego to Buffalo, returning Tue, Aug 25, priced at $282 found 3 days ago
Wed, Sep 2 - Wed, Sep 16
SAN
San Diego
BUF
Buffalo
$351 Roundtrip, found 4 days ago
$351
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Sep 2 from San Diego to Buffalo, returning Wed, Sep 16, priced at $351 found 4 days ago

Hotel Ideas near Buffalo Niagara Intl.

Airport Hotels near Buffalo Niagara Intl.

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
$127 nightly
The price is $145 total per night from Jun 23 to Jun 24
$145 total
Jun 23 - Jun 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (3,105 reviews)
"The pictures Hotels.com showed for this property were not the same as thus hotel was. Some of the picture on Hotels.com were completely inaccurate! Never had this issue with Expedia!"

Reviewed on Jun 22, 2026

Buffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
$116 nightly
The price is $132 total per night from Jul 19 to Jul 20
$132 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,166 reviews)
"Nice place"

Reviewed on Jun 22, 2026

Sleep Inn & Suites Buffalo Airport
Hilton Garden Inn Buffalo Airport

Hilton Garden Inn Buffalo Airport

3 out of 5
4201 Genesee St Buffalo NY
$144 nightly
The price is $163 total per night from Jun 28 to Jun 29
$163 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,004 reviews)
"Here’s a polished hotel review you can post: We had a wonderful stay at this hotel. Everything was very clean and well maintained. The staff was exceptionally kind, welcoming, and always ready to help. The buffet offered a great variety of delicious options and was well stocked throughout our stay. ..."

Reviewed on Jun 21, 2026

Hilton Garden Inn Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Buffalo

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
$127 nightly
The price is $145 total per night from Jun 23 to Jun 24
$145 total
Jun 23 - Jun 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (3,105 reviews)
"The pictures Hotels.com showed for this property were not the same as thus hotel was. Some of the picture on Hotels.com were completely inaccurate! Never had this issue with Expedia!"

Reviewed on Jun 22, 2026

Buffalo Airport Hotel
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
$104 nightly
The price is $118 total per night from Jun 29 to Jun 30
$118 total
Jun 29 - Jun 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the helpful staff and ...
7.6/10 Good! (2,432 reviews)
"This was by far the worst hotel I ever been at more like a motel the place was dirty they claim it was because of renovations the pictures looked nothing like pictures on line. The rooms was very oily and slippery just by far an horrible experience"

Reviewed on Jun 22, 2026

Garden Place Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
$116 nightly
The price is $132 total per night from Jul 19 to Jul 20
$132 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,166 reviews)
"Nice place"

Reviewed on Jun 22, 2026

Sleep Inn & Suites Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Buffalo Hotels With Airport Transportation

Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport

3 out of 5
4345 Genesee St Buffalo NY
$129 nightly
The price is $151 total per night from Jul 12 to Jul 13
$151 total
Jul 12 - Jul 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,326 reviews)
"This hotel is an absolute dump!!! Very dirty actually disgusting. Ceiling pealing and ac old and broken. There are many other hotels around and would never stay here again. On a positive note the staff was fabulous, very kind and friendly."

Reviewed on Jun 21, 2026

Comfort Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
$116 nightly
The price is $132 total per night from Jul 19 to Jul 20
$132 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,166 reviews)
"Nice place"

Reviewed on Jun 22, 2026

Sleep Inn & Suites Buffalo Airport
Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

5 out of 5
210 Franklin St Buffalo NY
$246 nightly
The price is $287 total per night from Jul 5 to Jul 6
$287 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this luxury hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (1,001 reviews)
"Excellent location . The hotel is gorgeous. Rooms are well maintained and comfortable. The pool is everything. Really enjoyed the stay here and I would stay here again if I come back."

Reviewed on Jun 14, 2026

Curtiss Hotel, an Ascend Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Buffalo Hotels

Red Roof Inn Buffalo - Niagara Airport

Red Roof Inn Buffalo - Niagara Airport

2 out of 5
146 Maple Drive Building A Bowmansville NY
$74 nightly
The price is $85 total per night from Jun 28 to Jun 29
$85 total
Jun 28 - Jun 29
Total with taxes and fees
Stay at this hotel in Bowmansville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (1,001 reviews)
"The environment and the staff"

Reviewed on Jun 21, 2026

Red Roof Inn Buffalo - Niagara Airport
Motel 6 Buffalo, NY - Airport - Williamsville

Motel 6 Buffalo, NY - Airport - Williamsville

2 out of 5
52 Freeman Rd Buffalo NY
Stay at this motel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.2/10 (1,206 reviews)
"One of the worst hotel I ever stayed in. The staff in not helpful, The staff asked for the deposit in cash when I asked for the receipt she said she will not give any receipt so I asked that I will do the card and she said she cant do that and an argument happened for an 20mins, there are no amenities ..."

Reviewed on Jun 14, 2026

Get rates
Motel 6 Buffalo, NY - Airport - Williamsville
Red Roof Inn PLUS+ University at Buffalo - Amherst

Red Roof Inn PLUS+ University at Buffalo - Amherst

2.5 out of 5
42 Flint Rd Buffalo NY
$86 nightly
The price is $98 total per night from Jun 23 to Jun 24
$98 total
Jun 23 - Jun 24
Total with taxes and fees
Stay at this hotel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Buffalo Zoo and Walden Galleria Mall are located ...
5.6/10 (1,000 reviews)
"The room was very clean, bed was comfortable and the shower had plenty of hot water and water pressure. Had no problems sleeping very well each night. Would recommend."

Reviewed on Jun 1, 2026

Red Roof Inn PLUS+ University at Buffalo - Amherst
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Buffalo

Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY

2.5 out of 5
164b Slade Ave Buffalo NY
$128 nightly
The price is $146 total per night from Jun 28 to Jun 29
$146 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,292 reviews)
"I picked this hotel because it had a pool and hot tub, but when we got there, they were closed for maintenance. Breakfast was okay, but not great. Staff were friendly and helpful."

Reviewed on Jun 20, 2026

Country Inn & Suites by Radisson, Buffalo South I-90, NY
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
$116 nightly
The price is $132 total per night from Jul 19 to Jul 20
$132 total
Jul 19 - Jul 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,166 reviews)
"Nice place"

Reviewed on Jun 22, 2026

Sleep Inn & Suites Buffalo Airport
Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG

3 out of 5
1290 Sweethome Rd Buffalo NY
$213 nightly
The price is $242 total per night from Jun 29 to Jun 30
$242 total
Jun 29 - Jun 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,003 reviews)
"Staybridge Amherst is our favorite Buffalo Hotel. They are very friendly. Theresa is awesome. My son was graduating from his medical residency and they had a gift left over from the Buffalo college graduates. They gave it to us. Very much appreciated act of kindness. This place is a good place to ..."

Reviewed on Jun 20, 2026

Staybridge Suites Buffalo-Amherst by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SAN to BUF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SAN to Buffalo Niagara Intl. Airport (BUF)?
As you can't fly direct from San Diego Intl. Airport (SAN) to Buffalo Niagara International Airport, a flight with just one stopover is your best bet. Southwest Airlines, Delta Air Lines and American Airlines are all reliable airlines that operate on this route.
What is the shortest flight from SAN to Buffalo Niagara International Airport?
The fastest you can fly from San Diego Intl. Airport (SAN) to Buffalo Niagara International Airport is 6 hours and 6 minutes. Pack a few things in your carry-on to keep you amused, like a gripping book or some Sudoku puzzles.
How many hours flight from San Diego Intl. Airport (SAN) to BUF?
From SAN to BUF, you'll be in your seat for around 6 hours and 11 minutes. Settle back, order a glass of Champagne and put on your noise-canceling earphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from SAN to Buffalo Niagara Intl. Airport (BUF)?
Indulge in some people-watching, have a coffee, get the blood pumping again .... Airport stopovers don't have to be annoying! If you're planning to travel from SAN to BUF, you can't fly direct. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore