Cheap flights from SAN to BUF (San Diego Intl. to Buffalo Niagara Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from SAN to BUF starting at $175 One Way, $349 Round Trip

Prices starting at $349 for return flights and $175 for one-way flights to Buffalo Niagara Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 24 - Wed, Oct 28
SAN
San Diego
BUF
Buffalo
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Oct 24 from San Diego to Buffalo, returning Wed, Oct 28, priced at $349 found 1 day ago
Sun, Oct 25 - Thu, Oct 29
SAN
San Diego
BUF
Buffalo
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select United flight, departing Sun, Oct 25 from San Diego to Buffalo, returning Thu, Oct 29, priced at $349 found 1 day ago
Sat, Oct 24 - Wed, Oct 28
SAN
San Diego
BUF
Buffalo
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 24 from San Diego to Buffalo, returning Wed, Oct 28, priced at $349 found 1 day ago
Sat, Oct 24 - Wed, Oct 28
SAN
San Diego
BUF
Buffalo
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, Oct 24 from San Diego to Buffalo, returning Wed, Oct 28, priced at $349 found 1 day ago
Sat, Oct 24 - Wed, Oct 28
SAN
San Diego
BUF
Buffalo
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 24 from San Diego to Buffalo, returning Wed, Oct 28, priced at $349 found 1 day ago

Hotel Ideas near Buffalo Niagara Intl.

Airport Hotels near Buffalo Niagara Intl.

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
$102 nightly
The price is $116 total per night from May 24 to May 25
$116 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (3,024 reviews)
"Pictures are deceiving. This place is a motel."

Reviewed on May 20, 2026

Buffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
$106 nightly
The price is $121 total per night from May 24 to May 25
$121 total
May 24 - May 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,125 reviews)
"Convenient location"

Reviewed on May 20, 2026

Sleep Inn & Suites Buffalo Airport
Hilton Garden Inn Buffalo Airport

Hilton Garden Inn Buffalo Airport

3 out of 5
4201 Genesee St Buffalo NY
$153 nightly
The price is $174 total per night from May 29 to May 30
$174 total
May 29 - May 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
"This is a wonderful hotel. A very nice lobby for meeting, eating and relaxing. Many were enjoying dinner and breakfast. Clean rooms and helpful staff. Beds and bathrooms were excellent. We enjoyed our daughter's graduation from Daemen thanks to all of you!"

Reviewed on May 18, 2026

Hilton Garden Inn Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Buffalo

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
The price is $125 total per night from May 25 to May 26
$125 total
per night
May 25 - May 26
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (2,753 reviews)
"The room was not clean; the shower tiles were rust and the tub was peeling. We were not able to get cable or wifi to work on our TV, we called twice, after the second time front desk said someone would come but no one did! My morning check out with Tiffany at front desk was HORRIBLE. I never received ..."

Reviewed on May 20, 2026

M Hotel Buffalo
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
The price is $116 total per night from May 24 to May 25
$116 total
per night
May 24 - May 25
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (3,024 reviews)
"Pictures are deceiving. This place is a motel."

Reviewed on May 20, 2026

Buffalo Airport Hotel
Studio 6 Corporate Extended Stay Buffalo Amherst NY

Studio 6 Corporate Extended Stay Buffalo Amherst NY

2.5 out of 5
125 Inn Keepers Ln Buffalo NY
The price is $80 total per night from May 26 to May 27
$80 total
per night
May 26 - May 27
Stay at this hotel in Buffalo. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Boulevard Place and Ellicott Creek Playhouse are located ...
6/10 (925 reviews)
"Don’t stay at this hotel, they are terrible. They don’t have clean room for a reservation that way booked days away from the date we supposed to stayed there. Nobody was at the front desk, we have to wait for the same lady that was vacuuming the floor to come and attend to us. The online pictures ..."

Reviewed on May 19, 2026

Studio 6 Corporate Extended Stay Buffalo Amherst NY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Buffalo Hotels With Airport Transportation

Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport

3 out of 5
4345 Genesee St Buffalo NY
The price is $150 total per night from May 31 to Jun 1
$150 total
per night
May 31 - Jun 1
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,310 reviews)
"Everything was very private and no one bothered you if you didn't want them to. The room was very nice and big and clean and perfect for our week long stay. The parking lot was very well lit so it felt very safe. Also had a great breakfast and right next to coffee shop if you wanted to get something ..."

Reviewed on May 13, 2026

Comfort Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
The price is $118 total per night from May 24 to May 25
$118 total
per night
May 24 - May 25
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,125 reviews)
"Convenient location"

Reviewed on May 20, 2026

Sleep Inn & Suites Buffalo Airport
Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

5 out of 5
210 Franklin St Buffalo NY
The price is $287 total per night from May 25 to May 26
$287 total
per night
May 25 - May 26
Book a stay at this luxury hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
9.4/10 Exceptional! (1,000 reviews)
"We loved the hot spring pool!"

Reviewed on May 14, 2026

Curtiss Hotel, an Ascend Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Buffalo Hotels

Red Roof Inn Buffalo - Niagara Airport

Red Roof Inn Buffalo - Niagara Airport

2 out of 5
146 Maple Drive Building A Bowmansville NY
$68 nightly
The price is $77 total per night from May 25 to May 26
$77 total
May 25 - May 26
Total with taxes and fees
Stay at this hotel in Bowmansville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,016 reviews)
"Very few towels, TV remote did not work. Run down. Checked out early, but was told I could not get a refund because I booked through Expedia. Not a good experience."

Reviewed on May 18, 2026

Red Roof Inn Buffalo - Niagara Airport
Motel 6 Buffalo, NY - Airport - Williamsville

Motel 6 Buffalo, NY - Airport - Williamsville

2 out of 5
52 Freeman Rd Buffalo NY
$71 nightly
The price is $81 total per night from May 25 to May 26
$81 total
May 25 - May 26
Total with taxes and fees
Stay at this motel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.2/10 (1,211 reviews)
"Exterior looked like it needed more attention, Elevator looked a bit grimy."

Reviewed on May 10, 2026

Motel 6 Buffalo, NY - Airport - Williamsville
Red Roof Inn PLUS+ University at Buffalo - Amherst

Red Roof Inn PLUS+ University at Buffalo - Amherst

2.5 out of 5
42 Flint Rd Buffalo NY
$89 nightly
The price is $101 total per night from May 21 to May 22
$101 total
May 21 - May 22
Total with taxes and fees
Stay at this hotel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Walden Galleria Mall and Northtown Center at Amherst ...
5.8/10 (1,005 reviews)
"Staff was friendly but the property needs A LOT of work."

Reviewed on May 18, 2026

Red Roof Inn PLUS+ University at Buffalo - Amherst
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Buffalo

Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY

2.5 out of 5
164b Slade Ave Buffalo NY
The price is $140 total per night from May 31 to Jun 1
$140 total
per night
May 31 - Jun 1
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,299 reviews)
"Staff was courteous and helpful"

Reviewed on May 20, 2026

Country Inn & Suites by Radisson, Buffalo South I-90, NY
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
The price is $118 total per night from May 24 to May 25
$118 total
per night
May 24 - May 25
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,125 reviews)
"Convenient location"

Reviewed on May 20, 2026

Sleep Inn & Suites Buffalo Airport
Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG

3 out of 5
1290 Sweethome Rd Buffalo NY
The price is $192 total per night from May 26 to May 27
$192 total
per night
May 26 - May 27
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,004 reviews)
"Had to get another room because first one smelled like a wet dog."

Reviewed on May 19, 2026

Staybridge Suites Buffalo-Amherst by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SAN to BUF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SAN to Buffalo Niagara Intl. Airport (BUF)?
As you can't fly direct from San Diego Intl. Airport (SAN) to Buffalo Niagara International Airport, a flight with just one stopover is your best bet. Southwest Airlines, Delta Air Lines and American Airlines are all reliable airlines that operate on this route.
What is the shortest flight from SAN to Buffalo Niagara International Airport?
The fastest you can fly from San Diego Intl. Airport (SAN) to Buffalo Niagara International Airport is 6 hours and 6 minutes. Pack a few things in your carry-on to keep you amused, like a gripping book or some Sudoku puzzles.
How many hours flight from San Diego Intl. Airport (SAN) to BUF?
From SAN to BUF, you'll be in your seat for around 6 hours and 11 minutes. Settle back, order a glass of Champagne and put on your noise-canceling earphones. It's time to rewatch your favorite TV shows.
What airlines have the most flights from SAN to Buffalo Niagara Intl. Airport (BUF)?
Indulge in some people-watching, have a coffee, get the blood pumping again .... Airport stopovers don't have to be annoying! If you're planning to travel from SAN to BUF, you can't fly direct. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore