Cheap flights from MHT to EYW (Manchester-Boston Regional to Key West Intl.)

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Cheap Flights from MHT to EYW starting at $217 One Way, $392 Round Trip

Prices starting at $392 for return flights and $217 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Dec 2 - Wed, Dec 9
MHT
Manchester
EYW
Key West
$392 Roundtrip, found 4 days ago
$392
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 2 from Manchester to Key West, returning Wed, Dec 9, priced at $392 found 4 days ago
Wed, Dec 2 - Wed, Dec 9
MHT
Manchester
EYW
Key West
$401 Roundtrip, found 4 days ago
$401
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 2 from Manchester to Key West, returning Wed, Dec 9, priced at $401 found 4 days ago
Wed, May 20 - Wed, May 27
MHT
Manchester
EYW
Key West
$401 Roundtrip, found 3 days ago
$401
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, May 20 from Manchester to Key West, returning Wed, May 27, priced at $401 found 3 days ago
Thu, Jul 2 - Wed, Jul 8
MHT
Manchester
EYW
Key West
$407 Roundtrip, found 6 days ago
$407
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 2 from Manchester to Key West, returning Wed, Jul 8, priced at $407 found 6 days ago
Thu, Jul 2 - Wed, Jul 8
MHT
Manchester
EYW
Key West
$451 Roundtrip, found 6 days ago
$451
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 2 from Manchester to Key West, returning Wed, Jul 8, priced at $451 found 6 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$399 nightly
The price is $449 total per night from May 21 to May 22
$449 total
May 21 - May 22
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,041 reviews)
Amazing!! Highly recommend. The two-room villa was perfect for our needs, and the property is beautiful!!

Reviewed on Apr 20, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$246 nightly
The price is $276 total per night from May 18 to May 19
$276 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,338 reviews)
The hotel is very nice and the pool area is beautiful. The hotel is located across from a nice, wide bike and walking path that is parallel to the ocean. It’s also walking distance to a couple of nice restaurants and the airport. We used uber or lyft several times and every time, the driver was there ...

Reviewed on Apr 18, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$222 nightly
The price is $250 total per night from May 10 to May 11
$250 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,008 reviews)
We really enjoyed staying at this property. They had a shuttle that made it very convenient to be able to go downtown and get picked up from downtown and come back to the hotel. We flew in, we never needed a car.We stayed there five days and four nights and really liked the property.And the staff ...

Reviewed on Apr 20, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$229 nightly
The price is $258 total per night from Apr 21 to Apr 22
$258 total
Apr 21 - Apr 22
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (2,120 reviews)
Excellent. Provides shuttle to Duval area.

Reviewed on Apr 19, 2026

Blue Flamingo Resort Key West
Beachside Resort & Residences

Beachside Resort & Residences

3.5 out of 5
3841 N Roosevelt Blvd Key West FL
$260 nightly
The price is $293 total per night from Apr 28 to Apr 29
$293 total
Apr 28 - Apr 29
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.6/10 Excellent! (2,158 reviews)
Beach and pool were nice. Shuttle didn’t have room for all residents who wanted to use it. There was no alternative means of transportation.

Reviewed on Apr 20, 2026

Beachside Resort & Residences
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Boulevard Key West FL
$283 nightly
The price is $319 total per night from May 18 to May 19
$319 total
May 18 - May 19
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,809 reviews)
This place is fabulous. Easy to get to town on the shuttle Only down side is airport noise

Reviewed on Apr 19, 2026

Margaritaville Beach House Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$222 nightly
The price is $250 total per night from May 10 to May 11
$250 total
May 10 - May 11
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,008 reviews)
We really enjoyed staying at this property. They had a shuttle that made it very convenient to be able to go downtown and get picked up from downtown and come back to the hotel. We flew in, we never needed a car.We stayed there five days and four nights and really liked the property.And the staff ...

Reviewed on Apr 20, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$246 nightly
The price is $276 total per night from May 18 to May 19
$276 total
May 18 - May 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,338 reviews)
The hotel is very nice and the pool area is beautiful. The hotel is located across from a nice, wide bike and walking path that is parallel to the ocean. It’s also walking distance to a couple of nice restaurants and the airport. We used uber or lyft several times and every time, the driver was there ...

Reviewed on Apr 18, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$227 nightly
The price is $255 total per night from May 18 to May 19
$255 total
May 18 - May 19
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,007 reviews)
Helpful staff, great pool and convenient location are big pluses for the Eden Hotel. The rooms are all different so it a luck of the draw situation but we made the best of it. I would return.

Reviewed on Apr 19, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$252 nightly
The price is $284 total per night from May 10 to May 11
$284 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,309 reviews)
Perfect location for our family vacation to Key West! Very friendly staff, clean rooms, basic continental breakfast (all pre-packaged).

Reviewed on Apr 20, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$197 nightly
The price is $222 total per night from Apr 22 to Apr 23
$222 total
Apr 22 - Apr 23
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,004 reviews)
Location! Location! Location! Seashell was a best-kept secret. It was a great deal for being so walkably close to downtown Key West and, to be honest, it looked a bit sketch from the street (faded paint and sign, construction company sign on a building, signs of construction) but the guy checking ...

Reviewed on Apr 19, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$249 nightly
The price is $278 total per night from Apr 22 to Apr 23
$278 total
Apr 22 - Apr 23
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,016 reviews)
Great place & location !!

Reviewed on Apr 19, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$330 nightly
The price is $372 total per night from May 19 to May 20
$372 total
May 19 - May 20
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,222 reviews)
Very nice property, great location, right near the beach(which is rare in Key West). Our only issue was the housekeeping services. We took the privacy sign off the door and were expecting to get the room cleaned while we were gone for the whole morning. Usually, thats when the cleaning is done. We ...

Reviewed on Apr 19, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.4/10 Very Good! (1,000 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
This is a beautiful resort full of amenities! Margaritas when you arrive, smoothies at the pool each day around noon, free airport and old town shuttles so we didn’t need to Uber anywhere, also coffee/water/cookies in the lobby daily. The beach is an easy walk across the street. The hotel is super ...

Reviewed on Apr 19, 2026

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$229 nightly
The price is $258 total per night from Apr 21 to Apr 22
$258 total
Apr 21 - Apr 22
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.2/10 Very Good! (2,120 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
Excellent. Provides shuttle to Duval area.

Reviewed on Apr 19, 2026

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MHT to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MHT Address & GPS
Address:
One Airport Road
Manchester NH, 03103
United States
IATA Code:
MHT
Longitude:
-71.438439
Latitude:
42.927862
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Manchester-Boston Regional Airport (MHT) to Key West Intl. Airport (EYW)?
As you can't fly nonstop from Manchester-Boston Regional Airport (MHT) to Key West Intl. Airport (EYW) at the moment, a flight with just one stop is the next best thing. American Airlines, United Airlines and JetBlue Airways are popular airlines that service this route.
What is the shortest flight from Manchester Airport to Key West Intl. Airport (EYW)?
Getting from Manchester Airport to Key West Intl. Airport takes at least 4 hours and 58 minutes. Enjoy a tipple and get stuck into that book — this is your chance to sit back and unwind.
How many hours flight from MHT to Key West Intl. Airport?
It typically takes about 5 hours and 3 minutes to get from Manchester-Boston Regional Airport (MHT) to EYW. You'll be in the sky for a decent amount of time, so contemplate bringing plenty of entertainment, like an engrossing book or a podcast.
What airlines have the most flights from Manchester Airport to Key West Intl. Airport?
For now, you won't find any direct flights between MHT and EYW. However, you will find flights with at least one stop. There's always a positive side — use the time to get the blood flowing again or do a little souvenir shopping!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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