Cheap flights from DEN to BUF (Denver Intl. to Buffalo Niagara Intl.)

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Cheap Flights from DEN to BUF starting at $65 One Way, $131 Round Trip

Prices starting at $131 for return flights and $65 for one-way flights to Buffalo Niagara Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Feb 25 - Sat, Feb 28
DEN
Denver
BUF
Buffalo
$131 Roundtrip, found 1 day ago
$131
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 25 from Denver to Buffalo, returning Sat, Feb 28, priced at $131 found 1 day ago
Wed, Feb 25 - Sat, Feb 28
DEN
Denver
BUF
Buffalo
$157 Roundtrip, found 1 day ago
$157
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 25 from Denver to Buffalo, returning Sat, Feb 28, priced at $157 found 1 day ago
Wed, Feb 25 - Sat, Feb 28
DEN
Denver
BUF
Buffalo
$179 Roundtrip, found 1 day ago
$179
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 25 from Denver to Buffalo, returning Sat, Feb 28, priced at $179 found 1 day ago
Wed, Feb 25 - Sat, Feb 28
DEN
Denver
BUF
Buffalo
$191 Roundtrip, found 1 day ago
$191
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 25 from Denver to Buffalo, returning Sat, Feb 28, priced at $191 found 1 day ago
Thu, Apr 16 - Sun, Apr 19
DEN
Denver
BUF
Buffalo
$219 Roundtrip, found 6 days ago
$219
Roundtrip
found 6 days ago
Select Delta flight, departing Thu, Apr 16 from Denver to Buffalo, returning Sun, Apr 19, priced at $219 found 6 days ago

Hotel Ideas near Buffalo Niagara Intl.

Buffalo Hotels With Airport Transportation

Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport

3 out of 5
4345 Genesee St Buffalo NY
The price is $112 total per night from Jan 6 to Jan 7
$112 total
per night
Jan 6 - Jan 7
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,264 reviews)
Easy stay, convi

Reviewed on Dec 9, 2025

Comfort Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
The price is $96 total per night from Jan 8 to Jan 9
$96 total
per night
Jan 8 - Jan 9
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,900 reviews)
Seamless and easy check-in and check-out. Except I had to get my card re-activated EVERYDAY because it stopped working EVERYDAY 😡 that was annoying. The jacuzzi room was spacious but the king bed was old and worn out. It sunk in when you laid on it. Breakfast was good. Staff was friendly

Reviewed on Dec 16, 2025

Sleep Inn & Suites Buffalo Airport
Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

5 out of 5
210 Franklin St Buffalo NY
The price is $232 total per night from Dec 22 to Dec 23
$232 total
per night
Dec 22 - Dec 23
Book a stay at this luxury hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
9.2/10 Wonderful! (1,002 reviews)
The room was spotless, amenities were great and moreover the staff was exceptionally excellent 👍 thanks once again.

Reviewed on Dec 10, 2025

Curtiss Hotel, an Ascend Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DEN to BUF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DEN Address & GPS
Address:
8500 Pena Boulevard
Denver CO, 80249-6340
United States
IATA Code:
DEN
Longitude:
-104.673098
Latitude:
39.851382
Time Zone:
America/Denver
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from DEN to Buffalo Niagara International Airport?
Forget about lengthy layovers or missing that connecting flight. Southwest Airlines will take you directly from Denver Airport to Buffalo Niagara International Airport.
What is the shortest flight from Denver Airport to Buffalo Niagara International Airport?
The quickest flight from Denver Airport to Buffalo Niagara International Airport is 5 hours and 17 minutes. Pack a few things in your carry-on to keep you amused, like that new best-seller or your travel journal.
How many hours flight from DEN to BUF?
The journey from Denver Airport to Buffalo Niagara International Airport takes an average of 5 hours and 23 minutes. A few TV shows, some light reading and a decent snooze will help make time zoom by.
What airlines have the most flights from Denver Airport to Buffalo Niagara International Airport?
Ready to organize your Denver to Buffalo airfare? Southwest Airlines should be your first choice. With 67 flights each month to choose from on this route, they have the ticket to your next awe-inspiring adventure.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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