Cheap flights from BUF to SAN (Buffalo Niagara Intl. to San Diego Intl.)

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Cheap Flights from BUF to SAN starting at $109 One Way, $217 Round Trip

Prices starting at $217 for return flights and $109 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Feb 6 - Tue, Feb 10
BUF
Buffalo
SAN
San Diego
$217 Roundtrip, found 3 days ago
$217
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Fri, Feb 6 from Buffalo to San Diego, returning Tue, Feb 10, priced at $217 found 3 days ago
Thu, Jan 22 - Mon, Jan 26
BUF
Buffalo
SAN
San Diego
$217 Roundtrip, found 14 hours ago
$217
Roundtrip
found 14 hours ago
Select JetBlue Airways flight, departing Thu, Jan 22 from Buffalo to San Diego, returning Mon, Jan 26, priced at $217 found 14 hours ago
Thu, Dec 4 - Thu, Dec 11
BUF
Buffalo
SAN
San Diego
$220 Roundtrip, found 16 hours ago
$220
Roundtrip
found 16 hours ago
Select JetBlue Airways flight, departing Thu, Dec 4 from Buffalo to San Diego, returning Thu, Dec 11, priced at $220 found 16 hours ago
Sun, Feb 8 - Wed, Feb 18
BUF
Buffalo
SAN
San Diego
$225 Roundtrip, found 4 days ago
$225
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Sun, Feb 8 from Buffalo to San Diego, returning Wed, Feb 18, priced at $225 found 4 days ago
Thu, Jan 29 - Thu, Feb 12
BUF
Buffalo
SAN
San Diego
$254 Roundtrip, found 3 days ago
$254
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Thu, Jan 29 from Buffalo to San Diego, returning Thu, Feb 12, priced at $254 found 3 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr, San Diego, CA
$158 nightly
The price is $182 total per night from Nov 23 to Nov 24
$182 total
Nov 23 - Nov 24
Total with taxes and fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (3,115 reviews)
Easy punctual airport shuttle even for our early morning flight. Great location, amenities. Pool areas are very nice and dinning is excellent.

Reviewed on Oct 23, 2025

Sheraton San Diego Resort
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
$114 nightly
The price is $131 total per night from Nov 2 to Nov 3
$131 total
Nov 2 - Nov 3
Total with taxes and fees
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Popular attractions Mission Bay and Mission ...
9/10 Wonderful! (197 reviews)
Very nice Hotel it was clean and very well taken care of. The rooms are beautiful. The staff were friendly and the breakfast was fresh and good. The best part is that they serve coffee and Tea all day!

Reviewed on Oct 26, 2025

Hampton Inn & Suites by Hilton San Diego SeaWorld
Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor

3.5 out of 5
San Diego
$78 nightly
The price is $88 total per night from Nov 24 to Nov 25
$88 total
Nov 24 - Nov 25
Total with taxes and fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, a rooftop terrace, and parking (surcharge). Our guests praise the helpful staff ...
7.8/10 Good! (1,085 reviews)
The staff was friendly and very helpful! We also were impressed that when our ac quit working they responded immediately and helped us change rooms within minutes. The friendly service was above and beyond our expectations.

Reviewed on Oct 24, 2025

Comfort Inn San Diego Airport At The Harbor
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
$226 nightly
The price is $262 total per night from Nov 25 to Nov 26
$262 total
Nov 25 - Nov 26
Total with taxes and fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,839 reviews)
Staff were incredibly kind and helpful, the market one location was extremely convenient with a great selection of food and drink. My room had a wonderful view as well as being very clean. Overall very pleased with my experience and would definitely stay there again.

Reviewed on Oct 22, 2025

Manchester Grand Hyatt San Diego
Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor

3.5 out of 5
San Diego
$78 nightly
The price is $88 total per night from Nov 24 to Nov 25
$88 total
Nov 24 - Nov 25
Total with taxes and fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, a rooftop terrace, and parking (surcharge). Our guests praise the helpful staff ...
7.8/10 Good! (1,085 reviews)
The staff was friendly and very helpful! We also were impressed that when our ac quit working they responded immediately and helped us change rooms within minutes. The friendly service was above and beyond our expectations.

Reviewed on Oct 24, 2025

Comfort Inn San Diego Airport At The Harbor
Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street, San Diego, CA
$295 nightly
The price is $342 total per night from Nov 23 to Nov 24
$342 total
Nov 23 - Nov 24
Total with taxes and fees
Stay at this 5-star luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,002 reviews)
The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel.

Reviewed on Oct 22, 2025

Pendry San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
$168 nightly
The price is $195 total per night from Oct 28 to Oct 29
$195 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,991 reviews)
Had a very nice time very satisfied definitely recommend

Reviewed on Oct 23, 2025

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr, San Diego, CA
$158 nightly
The price is $182 total per night from Nov 23 to Nov 24
$182 total
Nov 23 - Nov 24
Total with taxes and fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (3,115 reviews)
Easy punctual airport shuttle even for our early morning flight. Great location, amenities. Pool areas are very nice and dinning is excellent.

Reviewed on Oct 23, 2025

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave, San Diego, CA
$136 nightly
The price is $156 total per night from Nov 2 to Nov 3
$156 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,023 reviews)
We attend marine corps bootcamp graduation. The hotel was absolutely awesome they offered shuttle services.

Reviewed on Oct 24, 2025

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd, San Diego, CA
$94 nightly
The price is $107 total per night from Nov 2 to Nov 3
$107 total
Nov 2 - Nov 3
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.4/10 Very Good! (1,191 reviews)
Nice place, will stay there again when i return to san diego.

Reviewed on Oct 22, 2025

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway, San Diego, CA
$62 nightly
The price is $71 total per night from Oct 30 to Oct 31
$71 total
Oct 30 - Oct 31
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.4/10 (2,085 reviews)
The staff was very friendly and helpful.My room was clean and when I needed extra towels.The staff was more than happy to give them to me.The only problem was the security guard,he was a total dick head and that is no reflection on the staff.He was going above his pay grade.Other than that,I had ...

Reviewed on Oct 22, 2025

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S, San Diego, CA
$84 nightly
The price is $96 total per night from Nov 2 to Nov 3
$96 total
Nov 2 - Nov 3
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,475 reviews)
Our room was clean and comfortable. The cleaning staff does a great job. The matinance The laundry room was clean and convenient. The pool area was well kept and pool water temp was 80 degrees F. The hot tub was cleaned and the water temp was 100 degrees F

Reviewed on Oct 23, 2025

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr, San Diego, CA
$183 nightly
The price is $211 total per night from Oct 29 to Oct 30
$211 total
Oct 29 - Oct 30
Total with taxes and fees
Stay at this 3.5-star beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (1,749 reviews)
Loved this hotel that sits right on the water! Staff was friendly and accommodating, easy parking in front of your room, good restaurants, and located in a lovely area of Mission Beach!

Reviewed on Oct 22, 2025

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
$166 nightly
The price is $191 total per night from Nov 23 to Nov 24
$191 total
Nov 23 - Nov 24
Total with taxes and fees
Stay at this 3.5-star hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular ...
8.8/10 Excellent! (3,803 reviews)
Beautiful location

Reviewed on Oct 24, 2025

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard, San Diego, CA
$215 nightly
The price is $248 total per night from Nov 9 to Nov 10
$248 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this 4-star beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,072 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
The location was perfect. Restaurants and the beach were within walking distance.

Reviewed on Oct 20, 2025

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

BUF to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
While you can't fly directly from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN), there are several air carriers that operate on this route with only one stopover. Why not find out if the dates and times available with Southwest Airlines or Delta Air Lines complement your travel plans? If they don't, there's always American Airlines.
What is the shortest flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
From Buffalo, the unique sights and sounds of San Diego are 7 hours and 7 minutes away. Choose your favorite seat, or maybe even one with a little more legroom, and jet to your destination in total comfort.
How many hours flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Airport?
It usually takes about 7 hours and 14 minutes to jet from BUF to SAN. Breeze through the journey by watching TV shows and reading magazines. Alternatively, squeeze in a bit of shut-eye.
What airlines have the most flights from Buffalo Niagara International Airport to SAN?
Watch the planes take off and land, have a coffee, strike up a conversation with a stranger ... Airport stopovers don't have to be annoying! If you're planning to travel from BUF to SAN, you can't fly direct. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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