Cheap flights from BUF to SAN (Buffalo Niagara Intl. to San Diego Intl.)

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Cheap Flights from BUF to SAN starting at $108 One Way, $215 Round Trip

Prices starting at $215 for return flights and $108 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Oct 24 - Wed, Oct 28
BUF
Buffalo
SAN
San Diego
$215 Roundtrip, found 3 days ago
$215
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Oct 24 from Buffalo to San Diego, returning Wed, Oct 28, priced at $215 found 3 days ago
Sat, Oct 24 - Wed, Oct 28
BUF
Buffalo
SAN
San Diego
$215 Roundtrip, found 3 days ago
$215
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Sat, Oct 24 from Buffalo to San Diego, returning Wed, Oct 28, priced at $215 found 3 days ago
Sat, Oct 24 - Wed, Oct 28
BUF
Buffalo
SAN
San Diego
$218 Roundtrip, found 3 days ago
$218
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Oct 24 from Buffalo to San Diego, returning Wed, Oct 28, priced at $218 found 3 days ago
Sat, Oct 24 - Wed, Oct 28
BUF
Buffalo
SAN
San Diego
$219 Roundtrip, found 3 days ago
$219
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Sat, Oct 24 from Buffalo to San Diego, returning Wed, Oct 28, priced at $219 found 3 days ago
Wed, Oct 21 - Sat, Oct 24
BUF
Buffalo
SAN
San Diego
$220 Roundtrip, found 4 days ago
$220
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Oct 21 from Buffalo to San Diego, returning Sat, Oct 24, priced at $220 found 4 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (3,688 reviews)
"Specifically the check-in staff was super helpful upon arrival !"

Reviewed on Sep 18, 2026

Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$184 nightly
The price is $213 total per night from Sep 28 to Sep 29
$213 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,318 reviews)
"Clean"

Reviewed on Sep 18, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$118 nightly
The price is $136 total per night from Oct 5 to Oct 6
$136 total
Oct 5 - Oct 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$118 nightly
The price is $136 total per night from Oct 5 to Oct 6
$136 total
Oct 5 - Oct 6
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
$85 nightly
The price is $97 total per night from Sep 20 to Sep 21
$97 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
8/10 Very Good! (3,915 reviews)
"Had to switch rooms initially, first room had dirt, grime and stickiness all over, including the air. The sliding glass door had a fly stuck in it with a hole in the screen. Very old, very dirty but the second room I checked into was much cleaner but still just not comfortable. A family members room ..."

Reviewed on Sep 18, 2026

Best Western Seven Seas
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$254 nightly
The price is $292 total per night from Oct 4 to Oct 5
$292 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,879 reviews)
"My s"

Reviewed on Sep 18, 2026

Paradise Point Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$184 nightly
The price is $213 total per night from Sep 28 to Sep 29
$213 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,318 reviews)
"Clean"

Reviewed on Sep 18, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Sep 27 to Sep 28
$245 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (3,688 reviews)
"Specifically the check-in staff was super helpful upon arrival !"

Reviewed on Sep 18, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$141 nightly
The price is $162 total per night from Sep 23 to Sep 24
$162 total
Sep 23 - Sep 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$75 nightly
The price is $86 total per night from Sep 20 to Sep 21
$86 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.6/10 Excellent! (1,560 reviews)
"Older place, clean, safe, quiet. Value. The towels were pretty thin but everything was clean. Easy access to kids college for pick up and drop off."

Reviewed on Sep 17, 2026

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$71 nightly
The price is $81 total per night from Sep 20 to Sep 21
$81 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,205 reviews)
"It was good, but the toilet was broken and had to take off the lid to flush it."

Reviewed on Sep 18, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$97 nightly
The price is $111 total per night from Oct 14 to Oct 15
$111 total
Oct 14 - Oct 15
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,760 reviews)
"Great experience"

Reviewed on Sep 18, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$223 nightly
The price is $257 total per night from Oct 19 to Oct 20
$257 total
Oct 19 - Oct 20
Total with taxes and fees
Book a stay at this business-friendly resort in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the pool ...
8.8/10 Excellent! (2,406 reviews)
"We were on the end of the 4th floor ina Bay View Junior Suite. Liked the spacious comfortable room, the large balcony with (an obstructed) view of the bay, Liked the kitchenette, refrig, many electrical outlets, comfortable chair. Big closet with mirrors and good drawer space. Quiet hallway, elevator. ..."

Reviewed on Sep 18, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$194 nightly
The price is $223 total per night from Sep 29 to Sep 30
$223 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,438 reviews)
"Another of my go to hotels when fishing out of seaforth. Right across the street from the landing. Rooms are clean and nice. Parking is tight though. They need bigger stalls."

Reviewed on Sep 18, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$245 nightly
The price is $282 total per night from Oct 18 to Oct 19
$282 total
Oct 18 - Oct 19
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

BUF to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
While you can't fly directly from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN), there are several air carriers that operate on this route with only one stopover. Why not find out if the dates and times available with Southwest Airlines or Delta Air Lines complement your travel plans? If they don't, there's always American Airlines.
What is the shortest flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
From Buffalo, the unique sights and sounds of San Diego are 7 hours and 7 minutes away. Choose your favorite seat, or maybe even one with a little more legroom, and jet to your destination in total comfort.
How many hours flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Airport?
It usually takes about 7 hours and 14 minutes to jet from BUF to SAN. Breeze through the journey by watching TV shows and reading magazines. Alternatively, squeeze in a bit of shut-eye.
What airlines have the most flights from Buffalo Niagara International Airport to SAN?
Watch the planes take off and land, have a coffee, strike up a conversation with a stranger ... Airport stopovers don't have to be annoying! If you're planning to travel from BUF to SAN, you can't fly direct. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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