Cheap flights from BUF to SAN (Buffalo Niagara Intl. to San Diego Intl.)

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Cheap Flights from BUF to SAN starting at $164 One Way, $327 Round Trip

Prices starting at $327 for return flights and $164 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Oct 26 - Thu, Oct 29
BUF
Buffalo
SAN
San Diego
$327 Roundtrip, found 8 hours ago
$327
Roundtrip
found 8 hours ago
Select Southwest Airlines flight, departing Mon, Oct 26 from Buffalo to San Diego, returning Thu, Oct 29, priced at $327 found 8 hours ago
Mon, Oct 26 - Thu, Oct 29
BUF
Buffalo
SAN
San Diego
$327 Roundtrip, found 8 hours ago
$327
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Oct 26 from Buffalo to San Diego, returning Thu, Oct 29, priced at $327 found 8 hours ago
Mon, Oct 26 - Thu, Oct 29
BUF
Buffalo
SAN
San Diego
$327 Roundtrip, found 8 hours ago
$327
Roundtrip
found 8 hours ago
Select Delta flight, departing Mon, Oct 26 from Buffalo to San Diego, returning Thu, Oct 29, priced at $327 found 8 hours ago
Fri, Oct 2 - Fri, Oct 9
BUF
Buffalo
SAN
San Diego
$327 Roundtrip, found 3 days ago
$327
Roundtrip
found 3 days ago
Select United flight, departing Fri, Oct 2 from Buffalo to San Diego, returning Fri, Oct 9, priced at $327 found 3 days ago
Thu, Oct 1 - Sun, Oct 4
BUF
Buffalo
SAN
San Diego
$331 Roundtrip, found 15 hours ago
$331
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Oct 1 from Buffalo to San Diego, returning Sun, Oct 4, priced at $331 found 15 hours ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from Aug 23 to Aug 24
$194 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$216 nightly
The price is $250 total per night from Sep 7 to Sep 8
$250 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,778 reviews)
"Pool"

Reviewed on Aug 8, 2026

Manchester Grand Hyatt San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$269 nightly
The price is $309 total per night from Sep 7 to Sep 8
$309 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
$216 nightly
The price is $250 total per night from Sep 7 to Sep 8
$250 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
9/10 Wonderful! (2,778 reviews)
"Pool"

Reviewed on Aug 8, 2026

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Aug 12 to Aug 13
$211 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$169 nightly
The price is $194 total per night from Aug 23 to Aug 24
$194 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$136 nightly
The price is $156 total per night from Sep 1 to Sep 2
$156 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$110 nightly
The price is $126 total per night from Aug 13 to Aug 14
$126 total
Aug 13 - Aug 14
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$93 nightly
The price is $106 total per night from Aug 9 to Aug 10
$106 total
Aug 9 - Aug 10
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,165 reviews)
"You get what you pay for great location great price but no wifi unless you pay per device and the pool is always locked. Other then that 👍"

Reviewed on Aug 8, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$120 nightly
The price is $137 total per night from Aug 10 to Aug 11
$137 total
Aug 10 - Aug 11
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,768 reviews)
"This is my 2nd time staying here. I really like it. It’s clean convenient and staff is nice."

Reviewed on Aug 7, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$239 nightly
The price is $275 total per night from Sep 7 to Sep 8
$275 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (2,330 reviews)
"We had a wonderful stay at the Bahia Resort. The rooms were spacious, the cleaning staff came through every day, the restaurants were exceptional, and the property was very well maintained. The only downside was that for a few days there was a distinct smell of pot from our neighbors. It was not ..."

Reviewed on Aug 7, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$214 nightly
The price is $246 total per night from Sep 7 to Sep 8
$246 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$261 nightly
The price is $301 total per night from Sep 7 to Sep 8
$301 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

BUF to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
While you can't fly directly from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN), there are several air carriers that operate on this route with only one stopover. Why not find out if the dates and times available with Southwest Airlines or Delta Air Lines complement your travel plans? If they don't, there's always American Airlines.
What is the shortest flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Intl. Airport (SAN)?
From Buffalo, the unique sights and sounds of San Diego are 7 hours and 7 minutes away. Choose your favorite seat, or maybe even one with a little more legroom, and jet to your destination in total comfort.
How many hours flight from Buffalo Niagara Intl. Airport (BUF) to San Diego Airport?
It usually takes about 7 hours and 14 minutes to jet from BUF to SAN. Breeze through the journey by watching TV shows and reading magazines. Alternatively, squeeze in a bit of shut-eye.
What airlines have the most flights from Buffalo Niagara International Airport to SAN?
Watch the planes take off and land, have a coffee, strike up a conversation with a stranger ... Airport stopovers don't have to be annoying! If you're planning to travel from BUF to SAN, you can't fly direct. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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