$185 Cheap flight deals from Columbus (CMH) to Panama City (PTY)

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This Weekend's Flight Deals from Columbus to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 7 - Wed, Feb 18
CMH
John Glenn Columbus Intl.
PTY
Tocumen Intl.
$643 Roundtrip, found 8 hours ago
$643
Roundtrip
found 8 hours ago
Select Delta flight, departing Sat, Feb 7 from John Glenn Columbus Intl. to Tocumen Intl., returning Wed, Feb 18, priced at $643 found 8 hours ago

Airfares from $185 One Way, $435 Round Trip from Columbus to Panama City

Prices starting at $435 for return flights and $185 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Mar 31 - Thu, Apr 16
CMH
Columbus
PTY
Panama City
$435 Roundtrip, found 8 hours ago
$435
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Mar 31 from Columbus to Panama City, returning Thu, Apr 16, priced at $435 found 8 hours ago
Thu, Apr 16 - Tue, Apr 21
CMH
Columbus
PTY
Panama City
$439 Roundtrip, found 6 days ago
$439
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Apr 16 from Columbus to Panama City, returning Tue, Apr 21, priced at $439 found 6 days ago
Mon, Mar 30 - Thu, Apr 16
CMH
Columbus
PTY
Panama City
$442 Roundtrip, found 8 hours ago
$442
Roundtrip
found 8 hours ago
Select Delta flight, departing Mon, Mar 30 from Columbus to Panama City, returning Thu, Apr 16, priced at $442 found 8 hours ago
Sat, Apr 4 - Wed, Apr 8
CMH
Columbus
PTY
Panama City
$452 Roundtrip, found 1 day ago
$452
Roundtrip
found 1 day ago
Select United flight, departing Sat, Apr 4 from Columbus to Panama City, returning Wed, Apr 8, priced at $452 found 1 day ago
Wed, Aug 12 - Mon, Aug 24
CMH
Columbus
PTY
Panama City
$456 Roundtrip, just found
$456
Roundtrip
just found
Select American Airlines flight, departing Wed, Aug 12 from Columbus to Panama City, returning Mon, Aug 24, priced at $456 just found

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites
2.0-star property

Mahogany Suites

10/10 Exceptional! (1 review)

Mar 12 - Mar 15

3 night stay

Columbus (CMH) to Panama City (PTY)

American Airlines • Non-stop • Coach

Panama City (PTY) to Columbus (CMH)

Avianca • Non-stop • Coach
Price was $1,177, price is now $820 per person
$820
per person
found 1 day ago
Decapolis Hotel Panama City
4.0-star property

Decapolis Hotel Panama City

8.6/10 Excellent! (1,396 reviews)

Mar 10 - Mar 17

7 night stay

Columbus (CMH) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Price was $1,292, price is now $950 per person
$950
per person
found 1 day ago
This hotel came up to all my expectations. Good room, hot water, friendly staff, EXCELLENT food in Le Petit Bistro, excellent location.

Reviewed on Jan 22, 2026

Villa Caprichosa
3.0-star property

Villa Caprichosa

10/10 Exceptional! (39 reviews)

Mar 10 - Mar 17

7 night stay

Columbus (CMH) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Price was $1,379, price is now $1,038 per person
$1,038
per person
found 1 day ago
We were welcomed by the owner as soon as we arrived. She was very sweet and made us feel like we were home. She designed the whole Villa and it was stunning. The views are amazing and the rooms are bery comfortable. The restaurant was just as remarkable. We had our best meal in Panama while we were there. The chef is amazing and he personalizes every meal. He spent lots of time talking to us and even told me how to make his soup that I fell in love with. This a great place for a romantic getaway or some relaxing with friends. I highly recommend going there.

Reviewed on May 31, 2017

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More About Flying To Panama City from Columbus

Route Information for Flights from Columbus to Panama City

Origin Airport IATA Code
CMH
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Columbus to Panama City

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Download the cutting-edge Orbitz app for either Android or iPhone, and use it to check on the status of your upcoming flights from Columbus to Panama City at any time. These apps also make it easy for you to book discount hotel rates in your destination city and check for deals on future Columbus to Panama City flights.

Frequently asked questions

What is the shortest flight from Columbus to Panama City?
The fastest flight from John Glenn Columbus Intl. Airport (CMH) to Panama City (PTY-Tocumen Intl.) is 5 hours and 23 minutes. Slip a few things into your hand luggage to help pass the time, like a gripping book or a portable board game.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.