Casino Hotels in St. Louis, MO

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Featured St. Louis Casino Resorts & Hotels

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
The price is $117 per night
At Hollywood Casino & Hotel St. Louis, guests enjoy a casino, a nightclub, and a 24-hour gym. If you decide to drive, there's free parking. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, tours or tickets, and luggage storage. Additional amenities include free WiFi in public areas, conference space, and a 24-hour business center.
Lumiere Place Casino Hotel

Lumiere Place Casino Hotel

4 out of 5
999 N. 2nd St., St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $128 per night
Guests of Lumiere Place Casino Hotel enjoy features like a casino, free WiFi in public areas, and a business center. Self parking is available for USD 10 per night. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a computer station, express check-out, and wedding services.
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $117 per night
River City Casino & Hotel features a casino, a nightclub, and a 24-hour gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and tours or tickets. Additional amenities include free WiFi in public areas, a conference center, and a business center.
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
The price is $179 per night
Guests of Ameristar Casino Resort and Spa have access to a full-service spa, a casino, and a nightclub. The front desk has multilingual staff on hand 24/7 to help with luggage storage, concierge services, and dry cleaning/laundry. Other amenities at this luxury hotel include an indoor pool, an outdoor pool, and a 24-hour gym.
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

3 out of 5
1425 South 5th Street, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
The price is $79 per night
At Best Western Plus The Charles Hotel, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. There's free parking and a free area shuttle. The 24-hour front desk has multilingual staff ready to assist with luggage storage and dry cleaning/laundry. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5 out of 5
999 North Second Street, St. Louis, MO
Free Cancellation
The price is $336 per night
Guests of Four Seasons Hotel St Louis enjoy a full-service spa, an outdoor pool, and a 24-hour gym. You can put free offsite parking to good use if you drive. Multilingual staff at the 24-hour front desk can assist with securing valuables, dry cleaning/laundry, and tours or tickets. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury hotel include a sauna, a rooftop terrace, and free WiFi in public areas.
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $129 per night
Guests of Residence Inn by Marriott St Louis Downtown enjoy a 24-hour gym, free WiFi in public areas, and a business center. Self parking is offered for USD 15 per day. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include coffee/tea in a common area, a computer station, and a free grocery shopping service.
Econo Lodge & Suites Granite City

Econo Lodge & Suites Granite City

2 out of 5
3236 W Chain Of Rocks Rd, Granite City, IL
Free Cancellation
Reserve now, pay when you stay
The price is $59 per night
Econo Lodge & Suites Granite City features free WiFi in public areas, coffee in a common area, and a library. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to assist with securing valuables and concierge services. Additional amenities include express check-in, express check-out, and free newspapers.
Holiday Inn Express St. Louis Arpt - Maryland Hgts, an IHG Hotel

Holiday Inn Express St. Louis Arpt - Maryland Hgts, an IHG Hotel

2.5 out of 5
13615 Riverport Drive, I-70 & Earth City Expswy, Maryland Heights, MO
Free Cancellation
The price is $87 per night
Holiday Inn Express St. Louis Arpt - Maryland Hgts, an IHG Hotel features a 24-hour gym, free WiFi in public areas, and conference space. You can take advantage of free parking, along with a free area shuttle. The 24-hour front desk has staff standing by to help with concierge services, luggage storage, and dry cleaning/laundry. Additional amenities include a 24-hour business center, a computer station, and express check-in.
Country Inn & Suites by Radisson, St. Charles, MO

Country Inn & Suites by Radisson, St. Charles, MO

2.5 out of 5
1190 S Main St, St. Charles, MO
Free Cancellation
The price is $100 per night
Guests staying at Country Inn & Suites by Radisson, St. Charles, MO enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with concierge services, securing valuables, and luggage storage. Additional amenities include a business center, a library, and laundry facilities.
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
The price is $106 per night
Guests staying at Comfort Suites St Charles - St Louis enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a computer station.
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard, St. Louis, MO
Guests staying at Americas Best Value Inn St. Louis Downtown enjoy free WiFi in public areas, express check-out, and a TV in a common area. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with tours/tickets and luggage storage. Additional amenities include an ATM and a vending machine.
Drury Inn & Suites St. Louis Convention Center

Drury Inn & Suites St. Louis Convention Center

3 out of 5
711 N Broadway, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $103 per night
At Drury Inn & Suites St. Louis Convention Center, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 15 per day. The 24-hour front desk has staff standing by to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a spa tub, a business center, and coffee/tea in a common area.
Homewood Suites by Hilton St. Louis Riverport - Airport West

Homewood Suites by Hilton St. Louis Riverport - Airport West

3 out of 5
13639 Riverport Dr, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
The price is $93 per night
Guests of Homewood Suites by Hilton St. Louis Riverport - Airport West have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Free Cancellation
The price is $129 per night
Guests staying at Hyatt Regency St. Louis at The Arch enjoy a gym, a rooftop terrace, and free WiFi in public areas. Parking is available for USD 30.00 per night (USD 40.00 per day for valet parking), and there's also limo/town car service. The 24-hour front desk has multilingual staff ready to assist with securing valuables, concierge services, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include conference space, a 24-hour business center, and a computer station.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best St. Louis Casino Hotels

Donā€™t gamble on your room reservation on your next trip. Book a St. Louis hotel and casino and youā€™ll be in a prime spot for a memory-making getaway. Youā€™ll get everything you need: cozy quarters for a good nightā€™s sleep, excellent service and additional great perks like on-site restaurants and entertainment. Roll out of bed and be rolling at the tables in no timeā€”now thatā€™s how you make the most of a casino vacation in St. Louis.

Youā€™re always a winner at St. Louis casino resorts
When you stay at resorts with casinos, your adventure begins even if you donā€™t hit the slots. Check in and head to your room, where youā€™ll enjoy amenities fit for a king. Complimentary bath products, plush towels and luxurious sheets are just the start. Book a room with a view and take in the sights of St. Louis from your balcony. Thatā€™s called living the high life.

You might not want to show your hand at the tables, but there are no secrets here on Orbitz. We can help you win big on your rate at St. Louis resort casino hotels, with prices ranging from $59 to $336. Book with us, and save your money for your epic casino trip.

Recent Casino Resorts & Hotels Reviews

Live by Loews - St.Louis

Live by Loews - St.Louis

5/5 Excellent
"This was a beautiful stay. Very clean beautiful entrance. I would stay here again. Not to mention the customer service. "
A verified traveler stayed at Live by Loews - St.Louis
Posted 3 weeks ago
Live by Loews - St.Louis
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

5/5 Excellent
"We stayed at the Embassy suites in downtown St. Louis for one week while visiting family for the holidays. It definitely surpassed our expectations. The staff was extremely friendly and helpful 24 hours a day. Our room was always stocked with everything we could possibly need. Breakfast was delicious! We will definitely be staying here again!"
A verified traveler stayed at Embassy Suites by Hilton St. Louis Downtown
Posted 3 weeks ago
Embassy Suites by Hilton St. Louis Downtown
The Wildwood Hotel

The Wildwood Hotel

5/5 Excellent
"Easy check in, clean and comfortable room."
A verified traveler stayed at The Wildwood Hotel
Posted 3 weeks ago
The Wildwood Hotel