$44 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $44 One Way, $83 Round Trip

$83 return flights and $44 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIABogotáSeptember 26 to October 9$313
JFKBogotáSeptember 26 to September 29$393
MIALimaSeptember 27 to December 5$412
MIAQuitoSeptember 27 to October 14$413
JFKQuitoSeptember 26 to October 5$428
MIASao PauloSeptember 27 to October 19$495
MIASantiagoSeptember 26 to October 9$519
MIABelemSeptember 28 to October 2$644
MIASalvadorSeptember 28 to October 2$744
MIABuenos AiresSeptember 26 to October 4$771
LHRRio de JaneiroSeptember 26 to October 7$899
JFKSalvadorSeptember 28 to October 2$988
JFKCordobaSeptember 26 to October 11$997
LHRSao PauloSeptember 28 to October 3$1,392
SINSao PauloSeptember 28 to January 30$1,740
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238, Urb. Jorge Chavez, Callao, Lima
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,002 reviews)
"Clean room; good service"

Reviewed on Aug 29, 2025

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72, Barrio Getsemani, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...
7.6/10 Good! (495 reviews)
"The property was good it just sucks that it did not have hot water to shower the baby but other than that it was good"

Reviewed on Sep 12, 2025

Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca, Diagonal a las Aduanas, Tababela, Pichincha
The price is $65 total per night from Sep 20 to Sep 21
$65 total
per night
Sep 20 - Sep 21
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (712 reviews)
Quick and Easy
"Stay was great! quick ride in a taxi back and forth to the airport. Perfect"

Reviewed on Sep 9, 2025

Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A, Santiago, Region Metropolitana
Stay at this 4-star aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
"Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also."

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A, Santiago, Region Metropolitana
Stay at this 4-star aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
"Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also."

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15, Medellín
Fully refundableReserve now, pay when you stay
The price is $105 total per night from Sep 20 to Sep 21
$105 total
per night
Sep 20 - Sep 21
Stay at this 4-star business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,074 reviews)
We enjoyed it!
"Great atmosphere, nice views, room was nice. Excellent breakfast. Convenient and safe location."

Reviewed on Sep 15, 2025

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
The price is $127 total per night from Oct 18 to Oct 19
$127 total
per night
Oct 18 - Oct 19
Stay at this 4.5-star luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"Such an amazing hotel with so many wonderful staff that go out of their ways to help in any way possible Superb location near pretty much everything in el poblado"

Reviewed on Sep 14, 2025

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28, Bogotá, Distrito Capital
Fully refundableReserve now, pay when you stay
The price is $53 total per night from Sep 20 to Sep 21
$53 total
per night
Sep 20 - Sep 21
Stay at this 4-star spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.4/10 Very Good! (1,003 reviews)
"My room was exceptional."

Reviewed on Sep 15, 2025

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
The price is $84 total per night from Sep 29 to Sep 30
$84 total
per night
Sep 29 - Sep 30
Stay at this 3.5-star business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (404 reviews)
"Excellent location in downtown with best value and services. 10 minutes walk to shopping, theaters, restaurants, subway, and 1 block from main retail street (Av. Corrientes = 42nd St in NYC) for taking taxi."

Reviewed on Mar 12, 2023

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
"Great"

Reviewed on Sep 14, 2025

Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630, Buenos Aires, Capital Federal
Stay at this 3-star hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida Street are located ...
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is $69 total per night from Sep 22 to Sep 23
$69 total
per night
Sep 22 - Sep 23
Stay at this 4-star business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (585 reviews)
"I researched the area when booking, and this hotel from visual sites and ratings seems accommodating.. I checked off my boxes once I arrived. I was greeted and welcomed. A comfortable bed, a hot shower, and a cold room with A/C. They also offered breakfast, which hit the spot. The hotel is located ..."

Reviewed on Jun 9, 2025

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
The price is $203 total per night from Sep 21 to Sep 22
$203 total
per night
Sep 21 - Sep 22
Stay at this 4.5-star luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,008 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
"Good"

Reviewed on Sep 16, 2025

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67, Bogotá, Bogota D.C.
Stay at this 3-star hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions 93 Park and Movistar Arena are located ...
"Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ..."

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
The price is $143 total per night from Sep 28 to Sep 29
$143 total
per night
Sep 28 - Sep 29
Stay at this 4-star beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,003 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
"It was good the stay but food was poor"

Reviewed on Sep 11, 2025

Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito, Cartagena
Fully refundableReserve now, pay when you stay
The price is $144 total per night from Sep 29 to Sep 30
$144 total
per night
Sep 29 - Sep 30
Stay at this 4.5-star luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,192 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
"Good place"

Reviewed on Sep 16, 2025

Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

Orbitz provides convenient, one-stop shopping for travelers looking for budget flights to South America or any other low fare domestic or international air travel.

Innovative Orbitz Tools for the Trip Planner on the Move

Now it is even faster to find exclusive deals and book cheap South America flights from any location with our new Orbitz apps. These cutting-edge mobile tools are available free to anyone with an Android device, iPad, or iPhone. Look up South America's most popular attractions, best restaurants, and entertainment venues or check on your flights to South America and make changes to your itinerary while waiting in line for your latte.

Stay on Budget, Earn Miles with Bargain South America Flights

You can find amazing discount fares with Orbitz’s guaranteed low prices or take advantage of last-minute sales and special travel packages. You can also earn points towards your airline frequent flyer programs when you book qualified flights to South America. That means you can rack up money-saving points and miles for future use while saving money now.

We Are Just a Phone Call Away If You Need Us

Booking, changing, or canceling your South America flights is a breeze with Orbitz’s online and mobile tools, but that doesn't mean that we leave you hanging if you want to speak with one of our representatives. If you need help, just contact our Customer Service by email or phone. To enjoy a less stressful trip, be sure to sign up for instant alerts so we can send you any updates or delays relating to your flights to South America to your mobile phone or email.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.