$103 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $103 One Way, $238 Round Trip

$238 return flights and $103 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
JFKBogotáSeptember 26 to September 29$393
MIALimaSeptember 26 to September 28$443
MIAQuitoSeptember 27 to October 5$453
MIASao PauloSeptember 28 to October 5$535
MIASantiagoSeptember 26 to October 2$584
MIACordobaSeptember 27 to September 30$615
MIABuenos AiresSeptember 26 to September 28$756
FCOSao PauloSeptember 26 to October 8$765
MIARio de JaneiroSeptember 28 to October 4$770
LHRRio de JaneiroSeptember 26 to October 7$899
JFKBuenos AiresSeptember 26 to October 3$1,091
LHRSao PauloSeptember 28 to October 3$1,392
LHRBuenos AiresSeptember 26 to November 26$1,422
SINSantiagoSeptember 26 to September 28$1,723
BKKBogotáSeptember 27 to October 18$2,155
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238, Urb. Jorge Chavez, Callao, Lima
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,003 reviews)
"Clean room; good service"

Reviewed on Aug 29, 2025

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72, Barrio Getsemani, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...
7.6/10 Good! (495 reviews)
"The property was good it just sucks that it did not have hot water to shower the baby but other than that it was good"

Reviewed on Sep 12, 2025

Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca, Diagonal a las Aduanas, Tababela, Pichincha
The price is $65 total per night from Sep 24 to Sep 25
$65 total
per night
Sep 24 - Sep 25
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (712 reviews)
Quick and Easy
"Stay was great! quick ride in a taxi back and forth to the airport. Perfect"

Reviewed on Sep 9, 2025

Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A, Santiago, Region Metropolitana
Stay at this 4-star aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
"Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also."

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A, Santiago, Region Metropolitana
Stay at this 4-star aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
"Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also."

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15, Medellín
Fully refundableReserve now, pay when you stay
The price is $99 total per night from Sep 23 to Sep 24
$99 total
per night
Sep 23 - Sep 24
Stay at this 4-star business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,074 reviews)
We enjoyed it!
"Great atmosphere, nice views, room was nice. Excellent breakfast. Convenient and safe location."

Reviewed on Sep 15, 2025

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
The price is $146 total per night from Oct 13 to Oct 14
$146 total
per night
Oct 13 - Oct 14
Stay at this 4.5-star luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"Such an amazing hotel with so many wonderful staff that go out of their ways to help in any way possible Superb location near pretty much everything in el poblado"

Reviewed on Sep 14, 2025

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28, Bogotá, Distrito Capital
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.4/10 Very Good! (1,003 reviews)
"My room was exceptional."

Reviewed on Sep 15, 2025

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
The price is $84 total per night from Sep 29 to Sep 30
$84 total
per night
Sep 29 - Sep 30
Stay at this 3.5-star business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (404 reviews)
"Excellent location in downtown with best value and services. 10 minutes walk to shopping, theaters, restaurants, subway, and 1 block from main retail street (Av. Corrientes = 42nd St in NYC) for taking taxi."

Reviewed on Mar 12, 2023

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
"Great"

Reviewed on Sep 14, 2025

Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630, Buenos Aires, Capital Federal
Stay at this 3-star hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida Street are located ...
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is $71 total per night from Sep 23 to Sep 24
$71 total
per night
Sep 23 - Sep 24
Stay at this 4-star business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (585 reviews)
"I researched the area when booking, and this hotel from visual sites and ratings seems accommodating.. I checked off my boxes once I arrived. I was greeted and welcomed. A comfortable bed, a hot shower, and a cold room with A/C. They also offered breakfast, which hit the spot. The hotel is located ..."

Reviewed on Jun 9, 2025

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2, Cartagena, Bolivar
The price is $170 total per night from Sep 28 to Sep 29
$170 total
per night
Sep 28 - Sep 29
Stay at this 4.5-star luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,008 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
"Good"

Reviewed on Sep 16, 2025

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67, Bogotá, Bogota D.C.
Stay at this 3-star hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions 93 Park and Movistar Arena are located ...
"Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ..."

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
The price is $140 total per night from Sep 29 to Sep 30
$140 total
per night
Sep 29 - Sep 30
Stay at this 4-star beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,003 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
"It was good the stay but food was poor"

Reviewed on Sep 11, 2025

Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito, Cartagena
Fully refundableReserve now, pay when you stay
The price is $144 total per night from Sep 29 to Sep 30
$144 total
per night
Sep 29 - Sep 30
Stay at this 4.5-star luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,192 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
"Good place"

Reviewed on Sep 16, 2025

Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

End your search for discount fares on flights to South America. Orbitz has all the best prices on South America flights. With Orbitz, you can expect:

Cheap Deals on Flights to South America

We offer big discounts and last-minute savings on South America flights. We make it easy for you to research, plan, and book your flight to South America — all while offering great low fares. With guaranteed low prices and cutting-edge mobile tools, the perfect trip begins on Orbitz.

Travel Convenience on the Go

Get alerts, updates, or book your South America flight or other flights wherever you are. Download our free apps for iPhone, Android, and iPad or visit our mobile site at m.orbitz.com to conveniently review or change your air travel plans. We can also send free alerts about your South America flight to your email or mobile phone, so you get advance warning about potential disruptions and flight delays. Need to book a hotel with your South America flight? Access exclusive, mobile-only deals via our mobile site and free apps – even on the same day.

Great Customer Care

We want to make your travel booking experience smooth and easy, from planning and researching South America flights to the actual booking. If you want to cancel your flight to South America, many tickets can be conveniently cancelled online. Contact our Customer Service to make changes to your air ticket.

Miles or Points Toward Frequent Flyer Programs

Much like booking with an airline directly, you can earn frequent flyer miles or points on qualified flights to South America with Orbitz. When completing your booking, just fill in your frequent flyer number for the airline you are flying with or for one of its available partner airlines.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.