$145 Cheap flights to South America
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Top places to visit in South America
Cheap flights to South America from $145 One Way, $342 Round Trip
$342 return flights and $145 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| MIA | Lima | October 25 to November 1 | $573 |
| JFK | Quito | October 24 to October 28 | $607 |
| JFK | Bogotá | October 23 to November 3 | $718 |
| MIA | São Paulo | October 25 to October 29 | $808 |
| MIA | Santiago | October 24 to October 28 | $891 |
| JFK | Santiago | October 23 to November 1 | $904 |
| JFK | Salvador | October 25 to November 17 | $974 |
| LHR | Lima | October 25 to January 21 | $1,106 |
| LHR | Santiago | October 24 to November 27 | $1,163 |
| LHR | Rio de Janeiro | October 25 to October 28 | $1,219 |
| LCY | São Paulo | October 25 to October 27 | $1,615 |
| SIN | Santiago | October 23 to October 31 | $1,828 |
| BKK | São Paulo | October 23 to October 25 | $1,905 |
| SIN | Lima | October 23 to November 5 | $1,951 |
| SIN | Bogotá | October 23 to October 31 | $2,036 |
Find The Perfect Hotel For After Your Flight
Score Epic South America Accommodation Deals
Padama Hotel
"Near by the airport , accesible. I booked the suit with jacuzzi but I was not able to enjoy as there was no water pressure. Overall it’s is an okay hotel to sleep ."
Reviewed on Oct 17, 2026
Hotel Dorado Plaza Centro Histórico
"excelente ubicacion"
Reviewed on Sep 22, 2026
Quito Airport Suites
Altura Suites
Our Top South America Apartment Hotels
Altura Suites
Sites Hotel
"Only issue which isn’t their fault is there’s a bar that plays loud music until 12/1am"
Reviewed on Oct 17, 2026
Hotel Du Parc
Lancaster House
"Excellent staff and property!"
Reviewed on Oct 17, 2026
Score Epic South America Accommodation Deals
Rochester Classic
"The property is clean, and very well located for dinning, shopping, cultural life, touristic attractions. It is very important to know, if you decide to rent a car, that the property has NO PARKING available and there is NO STREET PARKING AROUND! There are several parking garages around but they ..."
Reviewed on Sep 12, 2026
Regal Pacific Buenos Aires
Concorde Hotel
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."
Reviewed on Mar 6, 2018
Almacruz Hotel y Centro de Convenciones
"Lo mejor"
Reviewed on Oct 15, 2026
Family Friendly Hotels in South America
Hotel Las Americas Torre del Mar
Families like: Outdoor pools, kids club, playground, miniature golf
"Ccc"
Reviewed on Oct 17, 2026
Agora Suites Self-Service Boutique Hotel
"Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ..."
Reviewed on Oct 29, 2024
Las Americas Casa de Playa
Hilton Cartagena
Need a Car For After Your Flight?
Economy
Compact
Midsize
SUV
South America
Get the absolute lowest prices on flights to South America by shopping with Orbitz. Orbitz is the most efficient travel planner around, allowing you to search, compare and book discount domestic and international flights fast. With cutting-edge mobile tools and access to frequent flier rewards programs, we have everything you need for both your routine and holiday excursions.
Book Your Flight To South America Using Your Mobile Device
New mobile app tools enable those with hand-held devices to scout out the best bargains and to secure tickets from any location. If you have an iPhone, iPad or Android device, you may take advantage of special discounts, only available to mobile device customers, when you book hotel rooms or car rentals on the same day as booking South America flights.
Avoid Check-In Hassles When Traveling On Flights to South America
Orbitz also provides an array of resources that can help you eliminate most check-in hassles. Detailed baggage information is continually available for South America flights. Mobile apps can also be used to share travel itineraries with family members or business associates.
Keeping Everyone Up To Date
When you download the free Orbitz mobile phone app, you can get regular and free flight updates. These will keep you informed of important scheduling changes. Updates can even be sent to several contacts, helping to keep everyone current on anticipated arrival times and all other relevant flight details.
Orbitz makes traveling on a budget very easy to do. We provide everything you need to plan your ideal trip from start to finish. Getting there and back again is a snap when you book your South America flight using Orbitz.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.