$134 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $134 One Way, $281 Round Trip

$281 return flights and $134 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIALimaMay 8 to May 19$479
MIAQuitoMay 8 to May 10$490
JFKBogotáMay 10 to May 13$656
MIACórdobaMay 9 to May 22$703
MIASantiagoMay 8 to May 12$755
MIABuenos AiresMay 10 to May 15$822
JFKRio de JaneiroMay 9 to May 18$831
JFKSão PauloMay 8 to June 2$908
LHRRio de JaneiroMay 9 to June 10$1,065
LGWBogotáMay 8 to May 24$1,073
LHRLimaMay 10 to June 20$1,189
LHRSão PauloMay 8 to May 15$1,227
LHRQuitoMay 8 to May 22$1,384
SINSantiagoMay 8 to May 24$1,598
LHRBuenos AiresMay 10 to May 24$1,645
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
The price is $25 total per night from May 6 to May 7
$25 total
per night
May 6 - May 7
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
7.4/10 Good! (1,000 reviews)
The hotel staff is not good. They charge a lot of money for airport taxi and water bottle.

Reviewed on Apr 5, 2026

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is $52 total per night from May 9 to May 10
$52 total
per night
May 9 - May 10
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (516 reviews)
No tuviemos agua caliente, solo tenia una llave de agua fria. Le falta mantenimiento a lss paredes y pisos. Renovarse

Reviewed on May 5, 2026

Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca Tababela Pichincha
The price is $49 total per night from May 6 to May 7
$49 total
per night
May 6 - May 7
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (738 reviews)
The stay was nice. The room was very clean.

Reviewed on Apr 15, 2026

Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Julio Martinez Pradanos ...
Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Julio Martinez Pradanos ...
Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
The price is $88 total per night from May 9 to May 10
$88 total
per night
May 9 - May 10
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,146 reviews)
El aire acondicionado no funcionaba bien y llame a recepción y me cambiaron de cuarto. Este hotel es excelente, es mi cuarta ocasión que me hospedo.

Reviewed on May 5, 2026

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundable
The price is $158 total per night from May 31 to Jun 1
$158 total
per night
May 31 - Jun 1
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
Best hotel in the city! I keep coming back and I refuse to stay anywhere else.

Reviewed on May 1, 2026

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
The price is $64 total per night from May 17 to May 18
$64 total
per night
May 17 - May 18
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.6/10 Excellent! (1,000 reviews)
A equipe atendeu a gente super bem , e o quarto é grande, água bem quente, nós gostamos muito

Reviewed on Apr 29, 2026

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
The price is $78 total per night from May 10 to May 11
$78 total
per night
May 10 - May 11
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (417 reviews)
Everything was good, I booked a room for my parents they love it, staff was so nice and kind, room was clean. Thank you!

Reviewed on Apr 3, 2026

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
The price is $129 total per night from May 9 to May 10
$129 total
per night
May 9 - May 10
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida Street are located ...
6.6/10 (301 reviews)
Good located and no expensive hotel in Buenos Aire
Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city.

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is $78 total per night from May 13 to May 14
$78 total
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (688 reviews)
Very friendly staff, perfect location, the rooms are not new but clean and comfortable. I would say there is room for improvement for the breakfast and also the drinks menu (stuff not available). But overall I would recommend this hotel and we will come back without a hesitation!

Reviewed on Apr 16, 2026

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $180 total per night from May 11 to May 12
$180 total
May 11 - May 12
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,005 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
Le personnel est très sympathique

Reviewed on May 4, 2026

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67 Bogotá Bogota D.C.
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Movistar Arena and Estadio Nemesio Camacho ...
9/10 Wonderful! (193 reviews)
Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ...

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $150 total per night from May 11 to May 12
$150 total
May 11 - May 12
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,005 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
Breakfast was fresh

Reviewed on Apr 22, 2026

Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $192 total per night from Jun 2 to Jun 3
$192 total
Jun 2 - Jun 3
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,424 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
Great friendly staff

Reviewed on May 4, 2026

Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

Reach your destination without breaking your budget by booking your flights to South America using Orbitz. We offer access to all of the best discounts on airfare, travel accommodations and even car rentals. Planning your trip and saving money are easier with Orbitz.

Get Discount Rates On Your South America Flight

Whether planning ahead or deciding to book your trip at the last minute, Orbitz will provide the lowest rates on South America flights. Using our free mobile phone apps will make you privy to a number of discounts that are unique to mobile phone users. These are perfect for harried travelers who want to find deals that they can qualify for on the same day.

Make Orbitz Your Official Travel Planner

Orbitz can be used for much more than comparing and booking a discount flight to South America. We also offer a variety of resources for securing the ideal travel accommodations while staying on budget. Travel tips, hotel reviews, customized suggestions and even detailed images can all be accessed through your mobile phone.

Build A Comprehensive Travel Itinerary

In addition to booking a low cost flight to South America, you can learn about the best places to visit, the best hotels to stay in and the preferred times for traveling. When you use Orbitz mobile phone apps you can also share your travel itineraries with friends and family members, all with just a few quick taps.

Using Orbitz to secure your South America flights can save you money and time. Perfect for both the early travel planner and the last minute journey: Orbitz offers phenomenal customer service and unbeatable convenience.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.