$106 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $106 One Way, $250 Round Trip

$250 return flights and $106 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIABogotáDecember 12 to December 14$501
MIALimaDecember 14 to December 19$555
MIASantiagoDecember 14 to December 24$656
MIASao PauloDecember 14 to December 24$710
JFKLimaDecember 12 to December 19$732
JFKQuitoDecember 12 to December 22$810
JFKBogotáDecember 13 to December 15$842
MIASalvadorDecember 12 to December 15$967
LHRRio de JaneiroDecember 12 to December 20$1,180
LHRBogotáDecember 13 to February 7$1,383
JFKSalvadorDecember 12 to December 16$1,507
LCYBuenos AiresDecember 13 to December 17$1,831
LHRLimaDecember 13 to January 2$2,223
JFKCordobaDecember 14 to January 7$2,312
LHRSalvadorDecember 13 to January 17$2,457
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
7.2/10 Good! (1,000 reviews)
Room was clean. Staff were helpful. Bed was comfortable.

Reviewed on Dec 2, 2025

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $63 total per night from Dec 17 to Dec 18
$63 total
Dec 17 - Dec 18
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (500 reviews)
What i needed for the night with courteous staff.

Reviewed on Dec 4, 2025

Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca Tababela Pichincha
$50 nightly
The price is $55 total per night from Jan 1 to Jan 2
$55 total
Jan 1 - Jan 2, 2026
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (718 reviews)
The room was very clean, the staff were very friendly and helpful. I especially like pick-up service seeing as I usually arrive at 3am.

Reviewed on Nov 9, 2025

Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also.

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also.

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $101 total per night from Dec 10 to Dec 11
$101 total
Dec 10 - Dec 11
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,097 reviews)
Breakfast had a few options and air conditioning was good , staff was pleasant and helpful

Reviewed on Nov 18, 2025

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $139 total per night from Dec 23 to Dec 24
$139 total
Dec 23 - Dec 24
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,000 reviews)
Everything is just wonderful

Reviewed on Dec 4, 2025

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.4/10 Very Good! (1,002 reviews)
The staff were so friendly. Excellent service

Reviewed on Dec 5, 2025

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $84 total per night from Dec 18 to Dec 19
$84 total
Dec 18 - Dec 19
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (407 reviews)
Mis padres estuvieron muy contentos con el servicio del hotel, el personal fue muy amable y colaborativo.

Reviewed on Nov 22, 2025

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $119 total per night from Dec 15 to Dec 16
$119 total
Dec 15 - Dec 16
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (999 reviews)
Staff was helpful and friendly. Location was good and safe. Walkable to restaurants. Breakfast was good and convenient. Room was clean, but the room and some furniture looks quite dated.

Reviewed on Nov 26, 2025

Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida Street are located ...
Good located and no expensive hotel in Buenos Aire
Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city.

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $80 total per night from Dec 12 to Dec 13
$80 total
Dec 12 - Dec 13
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (612 reviews)
The people are very friendly, the facilities are lovely and comfortable. It has a very interesting museum. It's well located.

Reviewed on Nov 20, 2025

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $163 total per night from Dec 13 to Dec 14
$163 total
Dec 13 - Dec 14
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
Clean room

Reviewed on Dec 3, 2025

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67 Bogotá Bogota D.C.
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Andino Shopping Center and Salitre Plaza ...
Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ...

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $132 total per night from Dec 13 to Dec 14
$132 total
Dec 13 - Dec 14
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,005 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
Great service and the front desk ppl is very kind

Reviewed on Nov 30, 2025

Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $171 total per night from Dec 15 to Dec 16
$171 total
Dec 15 - Dec 16
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,279 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
Updated room goodviews

Reviewed on Dec 7, 2025

Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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South America

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Orbitz understands that your travel plans may change. That’s why we make it simple to cancel your ticket for South America flights if necessary. All you have to do is contact the Orbitz Customer Service department to adjust your travel plans after booking. When you’re ready book your trip, just do a fresh search for the perfect flights to South America again.

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Low Prices for South America Flights

Orbitz has the scoop on cheap tickets and bargain airfare for flights to South America. You can research the best flights for your trip and make your reservations all on our website with the confidence that you’re getting a great price.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.