$127 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $127 One Way, $271 Round Trip

$271 return flights and $127 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIABogotáApril 10 to April 20$321
MIALimaApril 12 to April 21$389
MIAQuitoApril 10 to April 13$503
MIABuenos AiresApril 10 to April 15$728
MIACordobaApril 11 to April 24$806
MIASalvadorApril 12 to April 14$873
MIABelemApril 11 to April 20$901
MIARio de JaneiroApril 12 to April 27$1,066
LHRBogotáApril 12 to April 20$1,111
LGWLimaApril 11 to April 27$1,561
BKKSao PauloApril 11 to April 24$1,630
LHRQuitoApril 10 to April 17$1,633
LHRBuenos AiresApril 10 to April 20$1,651
BKKSantiagoApril 11 to April 18$1,796
LHRSantiagoApril 10 to April 12$2,379
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
$26 nightly
The price is $26 total per night from Apr 8 to Apr 9
$26 total
Apr 8 - Apr 9
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
7.4/10 Good! (1,001 reviews)
The hotel staff is not good. They charge a lot of money for airport taxi and water bottle.

Reviewed on Apr 5, 2026

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $78 total per night from Apr 8 to Apr 9
$78 total
Apr 8 - Apr 9
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca Tababela Pichincha
$60 nightly
The price is $65 total per night from Apr 8 to Apr 9
$65 total
Apr 8 - Apr 9
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (736 reviews)
Nice place! I’d stay again anytime 😊

Reviewed on Mar 31, 2026

Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $92 total per night from Apr 26 to Apr 27
$92 total
Apr 26 - Apr 27
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,143 reviews)
Excellent aparthotel. I felt right at home, the breakfast was very good, and the staff were incredibly friendly. Strategically location at El Poblado and near to train station (700 meters)..

Reviewed on Apr 5, 2026

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundable
$137 nightly
The price is $137 total per night from Apr 27 to Apr 28
$137 total
Apr 27 - Apr 28
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,007 reviews)
The best hotel in Medellin, 5 star rating

Reviewed on Apr 6, 2026

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $60 total per night from Apr 8 to Apr 9
$60 total
Apr 8 - Apr 9
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.4/10 Very Good! (1,006 reviews)
Cumplió las espectativas

Reviewed on Apr 7, 2026

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
The price is $80 total per night from Apr 15 to Apr 16
$80 total
per night
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Florida Street and ...
7.8/10 Good! (416 reviews)
Everything was good, I booked a room for my parents they love it, staff was so nice and kind, room was clean. Thank you!

Reviewed on Apr 3, 2026

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
The price is $120 total per night from Apr 12 to Apr 13
$120 total
per night
Apr 12 - Apr 13
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
This was our first stay in Argentina and everything was amazing. It would have been nice to have USB chargers in the room for cell phones. Still, the everyone was super nice and bilingual, as needed. Breakfast was very nice.

Reviewed on Mar 17, 2026

Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Florida Street and Plaza San Martin are located ...
6.6/10 (301 reviews)
Good located and no expensive hotel in Buenos Aire
Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city.

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is $71 total per night from Apr 16 to Apr 17
$71 total
per night
Apr 16 - Apr 17
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (681 reviews)
I really enjoyed my stay at Almacruz. The staff is amazing!

Reviewed on Mar 31, 2026

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is $211 total per night from Apr 28 to Apr 29
$211 total
per night
Apr 28 - Apr 29
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,004 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
Bed mattresses are older and soft in the middle. You cannot get a king size bed, only 2 doubles. A/C on non adjustable. Room is cold which is good but very cold in the morning. Restaurant has no ice cream.

Reviewed on Apr 5, 2026

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67 Bogotá Bogota D.C.
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Movistar Arena and Estadio Nemesio Camacho ...
9/10 Wonderful! (193 reviews)
Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ...

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is $182 total per night from Apr 8 to Apr 9
$182 total
per night
Apr 8 - Apr 9
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
It was the best of the best . Im coming back at the end of the year

Reviewed on Apr 5, 2026

Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
The price is $203 total per night from Apr 12 to Apr 13
$203 total
per night
Apr 12 - Apr 13
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,393 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
We love the hotel! Really safe, clean, organized, the ambiance is awesome! The staff are very nice, kind and with really good attitude.They explain everything really well. The food is amazing! The pool area really clean, and nice! We would love to come back for our next visit!

Reviewed on Apr 6, 2026

Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

Why search for low cost fares on your flights to South America when Orbitz offers the guaranteed lowest prices on foreign and domestic flights? When you travel with Orbitz you can benefit from:

Bargain Flights to South America

Orbitz offers massive discounts and substantial last-minute savings on your South America flights. Orbitz ensures that you can find, plan and reserve your flights any destination with ease, all while enjoying the guaranteed lowest prices available anywhere.

Cutting-Edge Mobile Tools to Keep You In The Know

Orbitz sends you free alerts and updates on your South America flight wherever you are in the world. Once you have downloaded the free app for your iPhone, Android, or iPad, you can review or alter any travel plans that you have made or even book a future flight for business or pleasure. If you need to reserve a hotel room when booking your flight, you will find exclusive deals on our mobile site.

Frequent Flyer Program Enrolment

Orbitz finds you the lowest fares, but you can still add your miles to your frequent flyer program to earn miles or points on selected flights to South America. When making your booking, reference your frequent flyer number to receive discounts in the future.

Outstanding Customer Service

Orbitz values your business and wants to ensure that all of your flights are as easy as possible to book. If you have booked a flight to South America but need to cancel it, you may be able to do so online. If you have any questions or need help, the dedicated Orbitz customer service team is always standing by.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.