$125 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $125 One Way, $303 Round Trip

$303 return flights and $125 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIALimaJuly 5 to July 16$525
MIASao PauloJuly 4 to July 24$595
MIACordobaJuly 5 to July 22$818
LHRLimaJuly 5 to July 15$1,166
LGWSao PauloJuly 6 to July 27$1,176
LGWBuenos AiresJuly 6 to July 14$1,182
LGWRio de JaneiroJuly 4 to July 20$1,227
LHRBogotáJuly 4 to July 20$1,361
FCOLimaJuly 4 to July 8$1,463
SINSao PauloJuly 6 to July 19$1,515
FCOCordobaJuly 5 to July 12$1,758
BKKSantiagoJuly 6 to July 20$1,782
FCOQuitoJuly 4 to August 27$1,999
BKKBuenos AiresJuly 6 to July 13$2,164
SINSantiagoJuly 5 to July 12$2,450
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238, Urb. Jorge Chavez, Callao, Lima
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star hotel in Callao. Enjoy free WiFi, room service, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (999 reviews)
"Great"

Reviewed on Jun 27, 2025

Padama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72, Barrio Getsemani, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...
7.6/10 Good! (488 reviews)
"Because is very close to my place vicit"

Reviewed on Mar 28, 2025

Hotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca, Diagonal a las Aduanas, Tababela, Pichincha
Book a stay at this business-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (702 reviews)
"It's a mature quiet property with beautiful grounds and wonderful animals including a friendly llama. I intend to stay here every time I come to Quito."

Reviewed on Jun 2, 2025

Quito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A, Santiago, Region Metropolitana
Stay at this 4-star aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Plaza de Armas ...
"Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also."

Reviewed on Mar 17, 2020

Altura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A, Santiago, Region Metropolitana
Stay at this 4-star aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Plaza de Armas ...
"Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also."

Reviewed on Mar 17, 2020

Altura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15, Medellín
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,032 reviews)
"All staff was incredibly attentive! Cleaning staff were too kind! Gorgeous view of the city! Excellent breakfast options. Servers Sebastian and Nicolas were amazing! Would definitely stay again!"

Reviewed on Jun 23, 2025

Sites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36, Medellín, Antioquia
Fully refundable
Stay at this 4.5-star luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,003 reviews)
"Suoer Breakfast! Cleanest+"

Reviewed on Jun 28, 2025

Hotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28, Bogotá, Distrito Capital
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.4/10 Very Good! (1,001 reviews)
"It was a good experience. People so friendly and helpful"

Reviewed on Jun 13, 2025

Lancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (402 reviews)
"Excellent location in downtown with best value and services. 10 minutes walk to shopping, theaters, restaurants, subway, and 1 block from main retail street (Av. Corrientes = 42nd St in NYC) for taking taxi."

Reviewed on Mar 12, 2023

Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764, Buenos Aires, Capital Federal
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (999 reviews)
"Very nice hotel and reasonably priced. Staff is quite friendly and responsive. Will stay there again."

Reviewed on May 12, 2025

Regal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630, Buenos Aires, Capital Federal
Stay at this 3-star hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida Street are located ...
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on Mar 6, 2018

Concorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (570 reviews)
"I researched the area when booking, and this hotel from visual sites and ratings seems accommodating.. I checked off my boxes once I arrived. I was greeted and welcomed. A comfortable bed, a hot shower, and a cold room with A/C. They also offered breakfast, which hit the spot. The hotel is located ..."

Reviewed on Jun 9, 2025

Almacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,000 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Lots of families over holiday weekend
"Hotel staff was nice and efficient. Breakfast buffet yummy. Beds comfortable. Balcony had only 2 straight back chairs and a table. This is more like a convention hotel vibe than a Caribbean vibe. Would NOT recommend 5 Rosario Island Tour through the hotel’s “Best Experiences” sub-contractor - expensive ..."

Reviewed on Jun 24, 2025

Hotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67, Bogotá, Bogota D.C.
Stay at this 3-star hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions 93 Park and Movistar Arena are located ...
"Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ..."

Reviewed on Oct 29, 2024

Agora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar, Cartagena, Bolivar
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,003 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
"Continues to be a great place. — planning to return 3 times this year. 2025 …. Excellent ……great staff ….."

Reviewed on Jun 28, 2025

Las Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito, Cartagena
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,083 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
"Beautiful"

Reviewed on Jun 30, 2025

Hilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

Traveling to South America and need a cheap flight? Orbitz has great deals on flights to South America right now. Plus, we offer big discounts on hotel rooms and car rentals for a great money-saving trip.

Find Low Cost Flights to South America Quickly and Hassle-Free

There are many Internet sites that promise cheap South America flights, but a busy, bargain-minded trip planner needs more than just budget air tickets. Not only does Orbitz offer the best deals for domestic and international air fare, but we also provide the resources and tools to help you plan your flights to South America, book your lodging, and look up key attractions in South America. Our easy search tools and guaranteed low prices let you budget your time and your money so you have more of both to spend on your vacation.

New Apps Make Booking South America Flights Easier Than Ever

You no longer need to be sitting at your computer to find amazing Orbitz sales for flights to South America now we offer cutting-edge mobile tools for many Android and iOS gadgets. These free apps allow you to run a search for discount air fare, look for special vacation packages, or check on your booked South America flights from any location. Some special deals are only available for mobile customers, so be sure to take advantage of these free downloads today.

Orbitz Customers Are Truly #1

Orbitz takes pride in providing the best customer experience possible, and that effort doesn't end with discount flights to South America or user-friendly mobile apps and web tools. Orbitz Customer Service is always ready to answer questions and help you with booking, planning, or canceling your South America flights. When you need us, we’re here for you!

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.