$106 Cheap flights to South America
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Top places to visit in South America
Cheap flights to South America from $106 One Way, $256 Round Trip
$256 return flights and $106 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
EWR
New York
BOG
Bogotá
$256 Roundtrip, found 3 days ago
$256
Roundtrip
found 3 days ago
MIA
Miami
BOG
Bogotá
$271 Roundtrip, found 4 days ago
$271
Roundtrip
found 4 days ago
MIA
Miami
LIM
Lima
$277 Roundtrip, found 5 days ago
$277
Roundtrip
found 5 days ago
MIA
Miami
GRU
Sao Paulo
$322 Roundtrip, found 4 hours ago
$322
Roundtrip
found 4 hours ago
EWR
New York
GRU
Sao Paulo
$324 Roundtrip, found 10 hours ago
$324
Roundtrip
found 10 hours ago
JFK
New York
BOG
Bogotá
$361 Roundtrip, found 6 days ago
$361
Roundtrip
found 6 days ago
EWR
New York
UIO
Quito
$378 Roundtrip, found 1 hour ago
$378
Roundtrip
found 1 hour ago
JFK
New York
UIO
Quito
$384 Roundtrip, found 4 hours ago
$384
Roundtrip
found 4 hours ago
JFK
New York
UIO
Quito
$426 Roundtrip, just found
$426
Roundtrip
just found
JFK
New York
LIM
Lima
$553 Roundtrip, found 6 days ago
$553
Roundtrip
found 6 days ago
JFK
New York
GRU
Sao Paulo
$592 Roundtrip, found 22 hours ago
$592
Roundtrip
found 22 hours ago
JFK
New York
SCL
Santiago
$653 Roundtrip, found 8 hours ago
$653
Roundtrip
found 8 hours ago
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| MIA | Lima | March 28 to April 8 | $417 |
| MIA | Quito | March 27 to March 31 | $530 |
| MIA | Santiago | March 28 to April 3 | $532 |
| JFK | Quito | March 29 to April 1 | $544 |
| JFK | Bogotá | March 29 to April 28 | $583 |
| MIA | Cordoba | March 29 to April 7 | $641 |
| MIA | Salvador | March 27 to April 10 | $958 |
| LHR | Bogotá | March 29 to April 7 | $1,497 |
| JFK | Salvador | March 29 to April 3 | $1,686 |
| LGW | Sao Paulo | March 28 to April 19 | $1,712 |
| LHR | Quito | March 29 to April 18 | $1,813 |
| BKK | Buenos Aires | March 28 to April 8 | $2,095 |
| LGW | Santiago | March 27 to April 11 | $2,881 |
| SIN | Rio de Janeiro | March 29 to April 3 | $3,319 |
| BKK | Santiago | March 29 to April 2 | $3,678 |
Find The Perfect Hotel For After Your Flight
Score Epic South America Accommodation Deals
Padama Hotel
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
Hotel Dorado Plaza Centro Histórico
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is $70 total per night from Apr 16 to Apr 17
$70 total
per night
Apr 16 - Apr 17
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (513 reviews)
This was not my choice in booking as my original choice was cancelled for some odd reason or another. No hot water and if we wanted hot water , there was an additional fee / upgrade nightly fee
Reviewed on Mar 2, 2026
Quito Airport Suites
E8-233 Conector Alpachaca Tababela Pichincha
The price is $45 total per night from Mar 29 to Mar 30
$45 total
per night
Mar 29 - Mar 30
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Altura Suites
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our Top South America Apartment Hotels
Altura Suites
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Sites Hotel
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
The price is $90 total per night from Apr 22 to Apr 23
$90 total
per night
Apr 22 - Apr 23
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,138 reviews)
The location was pleasant and the rooms were a nice size.The breakfast was plentiful and the hotel staff was cheerful except for of a prickly male night receptionist. Alex, the reservations manager was extremely personable and informative.
Reviewed on Mar 12, 2026
Hotel Du Parc
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundable
The price is $155 total per night from Mar 25 to Mar 26
$155 total
per night
Mar 25 - Mar 26
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
Nice rooms. Breakfast underwhelming.
Reviewed on Mar 23, 2026
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Lancaster House
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.4/10 Very Good! (1,003 reviews)
Great breakfast and big room . Property staff were incredible
Reviewed on Mar 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Score Epic South America Accommodation Deals
Rochester Classic
Esmeralda 542 Buenos Aires Capital Federal
The price is $75 total per night from Apr 5 to Apr 6
$75 total
per night
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (413 reviews)
Mis padres estuvieron muy contentos con el servicio del hotel, el personal fue muy amable y colaborativo.
Reviewed on Nov 22, 2025
Regal Pacific Buenos Aires
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
This was our first stay in Argentina and everything was amazing. It would have been nice to have USB chargers in the room for cell phones. Still, the everyone was super nice and bilingual, as needed. Breakfast was very nice.
Reviewed on Mar 17, 2026
Concorde Hotel
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Florida Street and Plaza San Martin are located ...
6.6/10 (301 reviews)
Good located and no expensive hotel in Buenos Aire
Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city.
Reviewed on Mar 6, 2018
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Almacruz Hotel y Centro de Convenciones
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is $79 total per night from Apr 4 to Apr 5
$79 total
per night
Apr 4 - Apr 5
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (675 reviews)
Staff are friendly and professional. Just as the reviews all say, breakfast buffet is plentiful! We stayed clear of the eggs, but the fruit, pastries, and a la carte items were all fresh and delicious. Room was basic but clean, atmosphere in the common areas (lobby, etc) is like something from another ...
Reviewed on Mar 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in South America
Hotel Las Americas Torre del Mar
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is $224 total per night from Apr 5 to Apr 6
$224 total
per night
Apr 5 - Apr 6
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,003 reviews)
Families like: Outdoor pools, kids club, playground, miniature golf
Travelers say...
Hotel is old and need some improvements and renovations. For example, new linens and bedding. But the positive side is that it is in an excellent location and the staff is remarkably professional and nice.
Reviewed on Mar 16, 2026
Agora Suites Self-Service Boutique Hotel
Calle 67B No. 60-67 Bogotá Bogota D.C.
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Movistar Arena and Estadio Nemesio Camacho ...
9/10 Wonderful! (193 reviews)
Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ...
Reviewed on Oct 29, 2024
Las Americas Casa de Playa
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
The price is $187 total per night from Apr 5 to Apr 6
$187 total
per night
Apr 5 - Apr 6
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,002 reviews)
Families like: Outdoor pools, waterslide, kids club, playground
Travelers say...
The entire property is well kept, rooms are clean and staff is very cordial.
Reviewed on Mar 20, 2026
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Hilton Cartagena
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
The price is $206 total per night from Mar 29 to Mar 30
$206 total
per night
Mar 29 - Mar 30
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,382 reviews)
Families like: Outdoor pools, waterslide, playground, close to beach
Travelers say...
Me and my family’s review is based on our experience we had at the Hilton during our five nights stay here. We were in contact with the hotel prior to arrival and spoke to multiple employees and explain to them. We are travelling with kids under the age of six and need connecting rooms to our surprise ...
Reviewed on Mar 22, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Need a Car For After Your Flight?
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Midsize
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South America
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Stay on Budget, Earn Miles with Bargain South America Flights
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Booking, changing, or canceling your South America flights is a breeze with Orbitz’s online and mobile tools, but that doesn't mean that we leave you hanging if you want to speak with one of our representatives. If you need help, just contact our Customer Service by email or phone. To enjoy a less stressful trip, be sure to sign up for instant alerts so we can send you any updates or delays relating to your flights to South America to your mobile phone or email.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.