Cheap flights from VPS to CLE (Northwest Florida Regional to Hopkins Intl.)

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Cheap Flights from VPS to CLE starting at $160 One Way, $315 Round Trip

Prices starting at $315 for return flights and $160 for one-way flights to Hopkins Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Hopkins Intl.

Airport Hotels near Hopkins Intl.

The Orbit Hotel, Trademark Collection by Wyndham

The Orbit Hotel, Trademark Collection by Wyndham

2.5 out of 5
21500 Brookpark Rd Fairview Park OH
$98 nightly
The price is $115 total per night from Mar 15 to Mar 16
$115 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Fairview Park. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
9.2/10 Wonderful! (1,710 reviews)
Clean room, friendly staff, convenient location.

Reviewed on Feb 20, 2026

The Orbit Hotel, Trademark Collection by Wyndham
Hilton Garden Inn Cleveland Airport

Hilton Garden Inn Cleveland Airport

3 out of 5
4900 Emerald Court SW Cleveland OH
$106 nightly
The price is $124 total per night from Mar 1 to Mar 2
$124 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,005 reviews)
Place . Room

Reviewed on Feb 17, 2026

Hilton Garden Inn Cleveland Airport
La Quinta Inn & Suites by Wyndham Cleveland - Airport North

La Quinta Inn & Suites by Wyndham Cleveland - Airport North

3 out of 5
4222 W 150th St Cleveland OH
$74 nightly
The price is $87 total per night from Feb 23 to Feb 24
$87 total
Feb 23 - Feb 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,945 reviews)
Love it

Reviewed on Feb 20, 2026

La Quinta Inn & Suites by Wyndham Cleveland - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Cleveland

Hotel Indigo Cleveland Downtown by IHG

Hotel Indigo Cleveland Downtown by IHG

3.5 out of 5
651 Huron Rd E Cleveland OH
$89 nightly
The price is $104 total per night from Mar 1 to Mar 2
$104 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,568 reviews)
loved the bed and shower.

Reviewed on Feb 20, 2026

Hotel Indigo Cleveland Downtown by IHG
La Quinta Inn & Suites by Wyndham Cleveland - Airport North

La Quinta Inn & Suites by Wyndham Cleveland - Airport North

3 out of 5
4222 W 150th St Cleveland OH
$74 nightly
The price is $87 total per night from Feb 23 to Feb 24
$87 total
Feb 23 - Feb 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,945 reviews)
Love it

Reviewed on Feb 20, 2026

La Quinta Inn & Suites by Wyndham Cleveland - Airport North
Hotel Cleveland, Autograph Collection

Hotel Cleveland, Autograph Collection

4 out of 5
24 Public Sq Cleveland OH
$108 nightly
The price is $127 total per night from Mar 1 to Mar 2
$127 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this historic hotel in Cleveland. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the helpful ...
9/10 Wonderful! (243 reviews)
Fantastic location and very comfortable room

Reviewed on Feb 20, 2026

Hotel Cleveland, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cleveland Hotels With Airport Transportation

Comfort Inn Cleveland Airport

Comfort Inn Cleveland Airport

2.5 out of 5
17550 Rosbough Blvd Middleburg Heights OH
$58 nightly
The price is $68 total per night from Feb 24 to Feb 25
$68 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Middleburg Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and ...
6.8/10 (575 reviews)
Elevators were dirty, stains on walls and door. My sink was not draining well, I had to call for bath room to be cleaned when I got there. other than that the breakfast is big and rom was comfortable.

Reviewed on Feb 20, 2026

Comfort Inn Cleveland Airport
Crowne Plaza Cleveland Airport by IHG

Crowne Plaza Cleveland Airport by IHG

3.5 out of 5
7230 Engle Rd Middleburg Heights OH
$77 nightly
The price is $91 total per night from Mar 22 to Mar 23
$91 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Middleburg Heights. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
7/10 Good! (1,002 reviews)
Nice room & building - great food at restaurant!

Reviewed on Feb 18, 2026

Crowne Plaza Cleveland Airport by IHG
Best Western Airport Inn & Suites Cleveland

Best Western Airport Inn & Suites Cleveland

2.5 out of 5
16501 Snow Rd Brook Park OH
$60 nightly
The price is $70 total per night from Feb 22 to Feb 23
$70 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Brook Park. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8/10 Very Good! (1,184 reviews)
This hotel was convenient and cozy. Staff was extremely courteous. The Desk did not have any available outlets...should be considered to be able to plug in ones computer.

Reviewed on Feb 20, 2026

Best Western Airport Inn & Suites Cleveland
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Cleveland Hotels

Red Roof Inn Cleveland Airport-Middleburg Heights

Red Roof Inn Cleveland Airport-Middleburg Heights

2 out of 5
17555 Bagley Rd Middleburg Heights OH
$54 nightly
The price is $63 total per night from Mar 5 to Mar 6
$63 total
Mar 5 - Mar 6
Total with taxes and fees
Stay at this hotel in Middleburg Heights. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...
6.6/10 (1,007 reviews)
Updating rooms

Reviewed on Feb 19, 2026

Red Roof Inn Cleveland Airport-Middleburg Heights
University Hotel & Suites

University Hotel & Suites

2 out of 5
3614 Euclid Ave Cleveland OH
Stay at this hotel in Cleveland. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Progressive Field and Rocket Arena are located ...
4.6/10 (999 reviews)
Do Not Stay Here
This hotel is not a good place to stay. The staff was polite, and the three gentlemen that manned the door were very helpful. But the condition is run down and it looked it. It is NOT handicap accessible. The showers were dirty (we had 2 rooms), the mattresses were wrapped in plastic (bedbugs? I ...

Reviewed on Dec 7, 2020

University Hotel & Suites
SkyLight Inn Cleveland - Willoughby

SkyLight Inn Cleveland - Willoughby

2.5 out of 5
34600 Maplegrove Rd Willoughby OH
$55 nightly
The price is $64 total per night from Feb 22 to Feb 23
$64 total
Feb 22 - Feb 23
Total with taxes and fees
Stay at this motel in Willoughby. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.4/10 (1,001 reviews)
Room was not clean staff was very rude and she claimed to be the manager. I was charged for the room on the 9th but didn't stay until the 13th.I was to pay at the property not weeks prior to the stay

Reviewed on Feb 16, 2026

SkyLight Inn Cleveland - Willoughby
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Cleveland

Extended Stay America Premier Suites - Cleveland - Independence

Extended Stay America Premier Suites - Cleveland - Independence

2.5 out of 5
6025 Jefferson Dr Independence OH
$74 nightly
The price is $87 total per night from Mar 1 to Mar 2
$87 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Independence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,795 reviews)
The smoke alarm went off at 3am in the whole building and the front desk attendant was nowhere to be found

Reviewed on Feb 18, 2026

Extended Stay America Premier Suites - Cleveland - Independence
Sonesta Simply Suites Cleveland Airport

Sonesta Simply Suites Cleveland Airport

3 out of 5
17525 Rosbough Dr Middleburg Heights OH
$69 nightly
The price is $81 total per night from Feb 21 to Feb 22
$81 total
Feb 21 - Feb 22
Total with taxes and fees
Stay at this hotel in Middleburg Heights. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our ...
6.4/10 (1,008 reviews)
Room cleaned as best for a hotel stay. No issues with check in or check out. No complaints further. Enjoy my evening.

Reviewed on Feb 16, 2026

Sonesta Simply Suites Cleveland Airport
Sonesta Simply Suites Cleveland Westlake

Sonesta Simply Suites Cleveland Westlake

3 out of 5
30100 Clemens Rd Westlake OH
$63 nightly
The price is $74 total per night from Feb 21 to Feb 22
$74 total
Feb 21 - Feb 22
Total with taxes and fees
Stay at this hotel in Westlake. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,001 reviews)
Courteous staff, fair clean, doors are not sealed so you will need to bring extra blankets or increase the heat. Kitchen utensils were old and burn from previous use. Nice location

Reviewed on Feb 19, 2026

Sonesta Simply Suites Cleveland Westlake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

VPS to CLE Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Northwest Florida Regional Airport (VPS) to CLE?
If you're flying from VPS to CLE, be prepared to change planes. American Airlines, Delta Air Lines and Southwest Airlines are some airlines that operate on this route with just one stopover. Use the layover to give your legs a stretch and get a bite to eat.
What is the shortest flight from Destin–Fort Walton Beach Airport to Cleveland Hopkins Intl. Airport?
The shortest flight time from Northwest Florida Regional Airport (VPS) to CLE is around 3 hours and 49 minutes. Grab a refreshment from the drink cart, hone your travel itinerary or make friends with your seat mate — you'll have plenty of time on this medium-haul journey.
How many hours flight from Northwest Florida Regional Airport (VPS) to Cleveland Hopkins Intl. Airport?
On a normal day, the flight from Destin–Fort Walton Beach Airport to Hopkins Intl. Airport (CLE) takes 3 hours and 54 minutes. If you're looking to be as comfortable as possible, think about upgrading your seat using miles or cash.
What airlines have the most flights from VPS to CLE?
You'll need to make one or more stopovers if you need to get from Destin–Fort Walton Beach Airport to Cleveland Hopkins Intl. Airport. For now, there aren't any airlines that advertise direct flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.