Cheap flights from VPS to CLE (Northwest Florida Regional to Hopkins Intl.)

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Cheap Flights from VPS to CLE starting at $144 One Way, $320 Round Trip

Prices starting at $320 for return flights and $144 for one-way flights to Hopkins Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Hopkins Intl.

Airport Hotels near Hopkins Intl.

The Orbit Hotel, Trademark Collection by Wyndham

The Orbit Hotel, Trademark Collection by Wyndham

2.5 out of 5
21500 Brookpark Rd Fairview Park OH
$114 nightly
The price is $134 total per night from Mar 3 to Mar 4
$134 total
Mar 3 - Mar 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Fairview Park. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...
9.2/10 Wonderful! (1,707 reviews)
Awesome room....great story told by desk attendant about hotel history

Reviewed on Mar 1, 2026

The Orbit Hotel, Trademark Collection by Wyndham
Hilton Garden Inn Cleveland Airport

Hilton Garden Inn Cleveland Airport

3 out of 5
4900 Emerald Court SW Cleveland OH
$106 nightly
The price is $124 total per night from Mar 8 to Mar 9
$124 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,002 reviews)
It was good

Reviewed on Feb 25, 2026

Hilton Garden Inn Cleveland Airport
La Quinta Inn & Suites by Wyndham Cleveland - Airport North

La Quinta Inn & Suites by Wyndham Cleveland - Airport North

3 out of 5
4222 W 150th St Cleveland OH
$70 nightly
The price is $82 total per night from Mar 8 to Mar 9
$82 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,949 reviews)
It was a good place clean and quite

Reviewed on Feb 28, 2026

La Quinta Inn & Suites by Wyndham Cleveland - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Cleveland

Hotel Indigo Cleveland Downtown by IHG

Hotel Indigo Cleveland Downtown by IHG

3.5 out of 5
651 Huron Rd E Cleveland OH
$95 nightly
The price is $112 total per night from Mar 29 to Mar 30
$112 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,587 reviews)
Room was big and bed was so comfortable

Reviewed on Mar 1, 2026

Hotel Indigo Cleveland Downtown by IHG
Hotel Cleveland, Autograph Collection

Hotel Cleveland, Autograph Collection

4 out of 5
24 Public Sq Cleveland OH
$108 nightly
The price is $127 total per night from Mar 15 to Mar 16
$127 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this historic hotel in Cleveland. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the helpful ...
9/10 Wonderful! (256 reviews)
Our room water nicely appointed , clean. The hotel is beautiful.

Reviewed on Feb 28, 2026

Hotel Cleveland, Autograph Collection
Hyatt Regency Cleveland At The Arcade

Hyatt Regency Cleveland At The Arcade

4 out of 5
420 Superior Ave E Cleveland OH
$140 nightly
The price is $165 total per night from Mar 2 to Mar 3
$165 total
Mar 2 - Mar 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Cleveland. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,123 reviews)
Great customer service, clean rooms and the pizza restaurant in the hotel as excellent!

Reviewed on Feb 26, 2026

Hyatt Regency Cleveland At The Arcade
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cleveland Hotels With Airport Transportation

Comfort Inn Cleveland Airport

Comfort Inn Cleveland Airport

2.5 out of 5
17550 Rosbough Blvd Middleburg Heights OH
$62 nightly
The price is $73 total per night from Mar 2 to Mar 3
$73 total
Mar 2 - Mar 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Middleburg Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and ...
6.8/10 (579 reviews)
The staff is nice. The breakfast is usually solid but the juice machine was broken. This was my 3rd time staying here. All 3 times the end has been awhile, almost broken. Sheets are wrinkled. The worst part is the smell of cigarette and marijuana throughout the whole hotel. Unfortunately will be ...

Reviewed on Feb 28, 2026

Comfort Inn Cleveland Airport
Crowne Plaza Cleveland Airport by IHG

Crowne Plaza Cleveland Airport by IHG

3.5 out of 5
7230 Engle Rd Middleburg Heights OH
$79 nightly
The price is $93 total per night from Mar 8 to Mar 9
$93 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Middleburg Heights. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
7/10 Good! (1,003 reviews)
Toilet seat was broken, shower/bath water diverter was broken.

Reviewed on Feb 28, 2026

Crowne Plaza Cleveland Airport by IHG
Best Western Airport Inn & Suites Cleveland

Best Western Airport Inn & Suites Cleveland

2.5 out of 5
16501 Snow Rd Brook Park OH
$64 nightly
The price is $75 total per night from Mar 2 to Mar 3
$75 total
Mar 2 - Mar 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Brook Park. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
8/10 Very Good! (1,190 reviews)
The hotel itself is in a weird location that is a bit creepy at night. It’s also old and everything is gray. Not particularly clean either.

Reviewed on Feb 28, 2026

Best Western Airport Inn & Suites Cleveland
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Cleveland Hotels

Red Roof Inn Cleveland Airport-Middleburg Heights

Red Roof Inn Cleveland Airport-Middleburg Heights

2 out of 5
17555 Bagley Rd Middleburg Heights OH
$54 nightly
The price is $63 total per night from Mar 8 to Mar 9
$63 total
Mar 8 - Mar 9
Total with taxes and fees
Stay at this hotel in Middleburg Heights. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular ...
6.6/10 (1,002 reviews)
Updating rooms

Reviewed on Feb 19, 2026

Red Roof Inn Cleveland Airport-Middleburg Heights
University Hotel & Suites

University Hotel & Suites

2 out of 5
3614 Euclid Ave Cleveland OH
Stay at this hotel in Cleveland. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Progressive Field and Rocket Arena are located ...
4.6/10 (999 reviews)
Do Not Stay Here
This hotel is not a good place to stay. The staff was polite, and the three gentlemen that manned the door were very helpful. But the condition is run down and it looked it. It is NOT handicap accessible. The showers were dirty (we had 2 rooms), the mattresses were wrapped in plastic (bedbugs? I ...

Reviewed on Dec 7, 2020

University Hotel & Suites
SkyLight Inn Cleveland - Willoughby

SkyLight Inn Cleveland - Willoughby

2.5 out of 5
34600 Maplegrove Rd Willoughby OH
$54 nightly
The price is $62 total per night from Mar 8 to Mar 9
$62 total
Mar 8 - Mar 9
Total with taxes and fees
Stay at this motel in Willoughby. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.2/10 (1,001 reviews)
This room was terrible! The room had a terrible order like old mop water has been used. The bed was super itchy and the covers smelled awful. Everything looks like it was half fasted cleaned. The bathroom was moldy and disgusting. I will never be back.

Reviewed on Feb 28, 2026

SkyLight Inn Cleveland - Willoughby
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Cleveland

Extended Stay America Premier Suites - Cleveland - Independence

Extended Stay America Premier Suites - Cleveland - Independence

2.5 out of 5
6025 Jefferson Dr Independence OH
$77 nightly
The price is $90 total per night from Mar 15 to Mar 16
$90 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Independence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,784 reviews)
Smell of drugs and alcohol in hallways, elevator was not convenient specifically when you have your kids. Not recommended

Reviewed on Mar 1, 2026

Extended Stay America Premier Suites - Cleveland - Independence
Sonesta Simply Suites Cleveland Airport

Sonesta Simply Suites Cleveland Airport

3 out of 5
17525 Rosbough Dr Middleburg Heights OH
$62 nightly
The price is $73 total per night from Mar 2 to Mar 3
$73 total
Mar 2 - Mar 3
Total with taxes and fees
Stay at this hotel in Middleburg Heights. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our ...
6.4/10 (1,002 reviews)
Pretty nice for the price

Reviewed on Feb 28, 2026

Sonesta Simply Suites Cleveland Airport
Sonesta Simply Suites Cleveland Westlake

Sonesta Simply Suites Cleveland Westlake

3 out of 5
30100 Clemens Rd Westlake OH
$68 nightly
The price is $80 total per night from Mar 2 to Mar 3
$80 total
Mar 2 - Mar 3
Total with taxes and fees
Stay at this hotel in Westlake. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,000 reviews)
Courteous staff, fair clean, doors are not sealed so you will need to bring extra blankets or increase the heat. Kitchen utensils were old and burn from previous use. Nice location

Reviewed on Feb 19, 2026

Sonesta Simply Suites Cleveland Westlake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

VPS to CLE Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Northwest Florida Regional Airport (VPS) to CLE?
If you're flying from VPS to CLE, be prepared to change planes. American Airlines, Delta Air Lines and Southwest Airlines are some airlines that operate on this route with just one stopover. Use the layover to give your legs a stretch and get a bite to eat.
What is the shortest flight from Destin–Fort Walton Beach Airport to Cleveland Hopkins Intl. Airport?
The shortest flight time from Northwest Florida Regional Airport (VPS) to CLE is around 3 hours and 49 minutes. Grab a refreshment from the drink cart, hone your travel itinerary or make friends with your seat mate — you'll have plenty of time on this medium-haul journey.
How many hours flight from Northwest Florida Regional Airport (VPS) to Cleveland Hopkins Intl. Airport?
On a normal day, the flight from Destin–Fort Walton Beach Airport to Hopkins Intl. Airport (CLE) takes 3 hours and 54 minutes. If you're looking to be as comfortable as possible, think about upgrading your seat using miles or cash.
What airlines have the most flights from VPS to CLE?
You'll need to make one or more stopovers if you need to get from Destin–Fort Walton Beach Airport to Cleveland Hopkins Intl. Airport. For now, there aren't any airlines that advertise direct flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.