Cheap flights from STL to EYW (Lambert-St. Louis Intl. to Key West Intl.)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Cheap Flights from STL to EYW starting at $281 One Way, $369 Round Trip
Prices starting at $369 for return flights and $281 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
STL
St. Louis
EYW
Key West
$369 Roundtrip, found 3 days ago
$369
Roundtrip
found 3 days ago
STL
St. Louis
EYW
Key West
$400 Roundtrip, found 6 days ago
$400
Roundtrip
found 6 days ago
STL
St. Louis
EYW
Key West
$403 Roundtrip, found 6 days ago
$403
Roundtrip
found 6 days ago
STL
St. Louis
EYW
Key West
$412 Roundtrip, found 19 hours ago
$412
Roundtrip
found 19 hours ago
STL
St. Louis
EYW
Key West
$419 Roundtrip, found 1 day ago
$419
Roundtrip
found 1 day ago
Hotel Ideas near Key West Intl.
Airport Hotels near Key West Intl.
Hyatt Vacation Club at Windward Pointe, Key West
3675 South Roosevelt Boulevard Key West FL
$226 nightly
The price is $254 total per night from Oct 28 to Oct 29
$254 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,323 reviews)
"Huge balcony was perfect for our family to enjoy sunrise/sunset. Room was clean and comfortable."
Reviewed on Oct 21, 2026
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$169 nightly
The price is $190 total per night from Oct 25 to Oct 26
$190 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,559 reviews)
"Room was very spacious and clean!"
Reviewed on Oct 21, 2026
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$137 nightly
The price is $154 total per night from Oct 29 to Oct 30
$154 total
Oct 29 - Oct 30
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,123 reviews)
"I didn’t like the front desk clerk who check us in, not friendly AT ALL!!! Did not feel welcome."
Reviewed on Oct 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Key West
Margaritaville Beach House Key West
2001 South Roosevelt Blvd Key West FL
$275 nightly
The price is $310 total per night from Oct 25 to Oct 26
$310 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,807 reviews)
"Not the same good times vibe as other Margaritaville locations, needs renovation and up keep and poor dining options . Really hope these things come in the future as we live Margaritaville in all other locations."
Reviewed on Oct 21, 2026
Havana Cabana at Key West
3420 N. Roosevelt Blvd Key West FL
$236 nightly
The price is $265 total per night from Oct 30 to Oct 31
$265 total
Oct 30 - Oct 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard Key West FL
$166 nightly
The price is $187 total per night from Oct 25 to Oct 26
$187 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Key West Hotels With Airport Transportation
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$137 nightly
The price is $154 total per night from Oct 29 to Oct 30
$154 total
Oct 29 - Oct 30
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,123 reviews)
"I didn’t like the front desk clerk who check us in, not friendly AT ALL!!! Did not feel welcome."
Reviewed on Oct 20, 2026
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$169 nightly
The price is $190 total per night from Oct 25 to Oct 26
$190 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,559 reviews)
"Room was very spacious and clean!"
Reviewed on Oct 21, 2026
Eden House
1015 Fleming St Key West FL
$171 nightly
The price is $192 total per night from Oct 27 to Oct 28
$192 total
Oct 27 - Oct 28
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Key West Hotels
Southwinds Motel
1321 Simonton Street Key West FL
$169 nightly
The price is $190 total per night from Oct 26 to Oct 27
$190 total
Oct 26 - Oct 27
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,389 reviews)
"We have stayed at this facility for the last two years now and have been very pleased with the staff, the grounds, and the condition of the rooms. We will be booking with them again next year."
Reviewed on Oct 21, 2026
Seashell Motel
718 South Street Key West FL
$136 nightly
The price is $153 total per night from Oct 28 to Oct 29
$153 total
Oct 28 - Oct 29
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,001 reviews)
"Great Place for one day but more I might look for a bigger place"
Reviewed on Oct 16, 2026
Duval House
815 Duval St Key West FL
$160 nightly
The price is $177 total per night from Oct 25 to Oct 26
$177 total
Oct 25 - Oct 26
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,121 reviews)
"Amazing location balcony was great to see gombay parade come by will be back"
Reviewed on Oct 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Key West
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$235 nightly
The price is $265 total per night from Oct 25 to Oct 26
$265 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy 3 outdoor pools, a full-service spa, and 2 poolside bars. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (3,634 reviews)
"You can't beat the location. It is easy to get to and around the area. I like being close to the beach and there is places to eat at on the property. I would stay here again. The rooms are clean but average. It was all we needed though. I was happy with the hotel pic."
Reviewed on Oct 21, 2026
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard Key West FL
$166 nightly
The price is $187 total per night from Oct 25 to Oct 26
$187 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
Hilton Key West Resort & Marina
5950 Peninsular Avenue Key West FL
$170 nightly
The price is $191 total per night from Oct 29 to Oct 30
$191 total
Oct 29 - Oct 30
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
STL to EYW Route Info
Origin Airport | |
|---|---|
Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
- Airport Locations
- More Popular Flights
- Top Trending
- Flights from Other Cities
- Flights From Other Airports
- Great Travel Ideas
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York
Other Flights from Lambert-St. Louis Intl. Airport (STL)
Other Flights to Key West Intl. Airport (EYW)
Top Trending
Flights
- DCA to MCO
- BOS to MCO
- BDL to MCO
- LGA to MIA
- JFK to LAS
- LGA to FLL
- MCO to LAX
- DTW to MCO
- DCA to MIA
- LAX to DFW
- MCO to LGA
- SEA to SAN
- BWI to MIA
- JFK to FLL
- BWI to DFW
- LAX to MCO
- EWR to MCO
- SNA to LAS
- LGA to MCO
- MCO to JFK
- MCO to EWR
- ORD to MCO
- MCO to SJU
- PHL to MCO
- BWI to MCO
- JFK to MCO
- JFK to MIA
- DFW to CDG
- RDU to MCO
- DCA to BOS
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.