Cheap flights from STL to EYW (Lambert-St. Louis Intl. to Key West Intl.)

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Cheap Flights from STL to EYW starting at $277 One Way, $392 Round Trip

Prices starting at $392 for return flights and $277 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jan 26 - Thu, Feb 18
STL
St. Louis
EYW
Key West
$392 Roundtrip, found 6 hours ago
$392
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Jan 26 from St. Louis to Key West, returning Thu, Feb 18, priced at $392 found 6 hours ago
Tue, Jan 26 - Thu, Feb 18
STL
St. Louis
EYW
Key West
$392 Roundtrip, found 6 hours ago
$392
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Jan 26 from St. Louis to Key West, returning Thu, Feb 18, priced at $392 found 6 hours ago
Tue, Jan 26 - Thu, Feb 18
STL
St. Louis
EYW
Key West
$420 Roundtrip, found 6 hours ago
$420
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Jan 26 from St. Louis to Key West, returning Thu, Feb 18, priced at $420 found 6 hours ago
Tue, Nov 3 - Sat, Nov 7
STL
St. Louis
EYW
Key West
$426 Roundtrip, found 8 hours ago
$426
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Nov 3 from St. Louis to Key West, returning Sat, Nov 7, priced at $426 found 8 hours ago
Sat, Oct 3 - Wed, Oct 7
STL
St. Louis
EYW
Key West
$428 Roundtrip, found 11 hours ago
$428
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Oct 3 from St. Louis to Key West, returning Wed, Oct 7, priced at $428 found 11 hours ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
Get rates
Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$152 nightly
The price is $171 total per night from Oct 1 to Oct 2
$171 total
Oct 1 - Oct 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,528 reviews)
"Everyone a pleasure to talk with ! concierge very helpful in planning with activities/restaurants! we loved having the shuttle!"

Reviewed on Sep 26, 2026

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$151 nightly
The price is $170 total per night from Sep 29 to Sep 30
$170 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,108 reviews)
"Basic and pretty clean, rooms need updating overall. Shuttle is nice"

Reviewed on Sep 26, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$168 nightly
The price is $189 total per night from Sep 28 to Sep 29
$189 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,691 reviews)
"Genial"

Reviewed on Sep 26, 2026

Blue Flamingo Resort Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$229 nightly
The price is $258 total per night from Sep 28 to Sep 29
$258 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,628 reviews)
"Nice place, but over priced"

Reviewed on Sep 27, 2026

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Blvd Key West FL
$265 nightly
The price is $298 total per night from Sep 28 to Sep 29
$298 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (1,802 reviews)
"Food and Drinks were excellent. Some things on the property were a bit run down. However, place was clean. Really nice pool and bar facilities. Beautiful beach."

Reviewed on Sep 26, 2026

Margaritaville Beach House Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$151 nightly
The price is $170 total per night from Sep 29 to Sep 30
$170 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,108 reviews)
"Basic and pretty clean, rooms need updating overall. Shuttle is nice"

Reviewed on Sep 26, 2026

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$152 nightly
The price is $171 total per night from Oct 1 to Oct 2
$171 total
Oct 1 - Oct 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,528 reviews)
"Everyone a pleasure to talk with ! concierge very helpful in planning with activities/restaurants! we loved having the shuttle!"

Reviewed on Sep 26, 2026

Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$142 nightly
The price is $160 total per night from Sep 28 to Sep 29
$160 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$155 nightly
The price is $174 total per night from Sep 28 to Sep 29
$174 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$101 nightly
The price is $114 total per night from Sep 28 to Sep 29
$114 total
Sep 28 - Sep 29
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$119 nightly
The price is $131 total per night from Oct 5 to Oct 6
$131 total
Oct 5 - Oct 6
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.6/10 Exceptional! (1,103 reviews)
"Fly in, Uber to and from the Duvall, fly home! Great place to have a fun time!"

Reviewed on Sep 25, 2026

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$229 nightly
The price is $258 total per night from Sep 28 to Sep 29
$258 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this spa hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.6/10 Excellent! (3,628 reviews)
"Nice place, but over priced"

Reviewed on Sep 27, 2026

Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$168 nightly
The price is $189 total per night from Sep 28 to Sep 29
$189 total
Sep 28 - Sep 29
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (2,691 reviews)

Families like: Outdoor pools, playground, miniature golf, game room

Travelers say...
"Genial"

Reviewed on Sep 26, 2026

Blue Flamingo Resort Key West
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

4 out of 5
5950 Peninsular Avenue Key West FL
$174 nightly
The price is $196 total per night from Sep 29 to Sep 30
$196 total
Sep 29 - Sep 30
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
Hilton Key West Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

STL to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Lambert Field to Key West Intl. Airport?
You're going to need to switch planes if you're wanting to fly from STL to Key West Intl. Airport. A range of companies offer services on this route with only one stopover, including American Airlines, United Airlines and Delta Air Lines.
What is the shortest flight from St. Louis Lambert International Airport to Key West Intl. Airport (EYW)?
The shortest flight from STL to EYW is 5 hours and 10 minutes. Pack a few things in your carry-on to keep you amused, like a magazine or a crossword puzzle.
How many hours flight from St. Louis Lambert International Airport to EYW?
Typically, it takes 5 hours and 15 minutes to fly from STL to EYW. Get through this medium-haul journey by watching movies and getting stuck into a good book. Alternatively, squeeze in a bit of shut-eye.
What airlines have the most flights from St. Louis Lambert International Airport to EYW?
Do some people-watching, pick up a doughnut, get the blood pumping again .... Airport stopovers don't have to be something to dread! If you're traveling between St. Louis and Key West, you won't find any direct flights. Prepare to make a stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.