Cheap flights from STL to EYW (Lambert-St. Louis Intl. to Key West Intl.)

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Cheap Flights from STL to EYW starting at $274 One Way, $358 Round Trip

Prices starting at $358 for return flights and $274 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 6 - Sat, Oct 10
STL
St. Louis
EYW
Key West
$358 Roundtrip, found 2 days ago
$358
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Oct 6 from St. Louis to Key West, returning Sat, Oct 10, priced at $358 found 2 days ago
Thu, Nov 5 - Tue, Nov 10
STL
St. Louis
EYW
Key West
$372 Roundtrip, found 2 days ago
$372
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Nov 5 from St. Louis to Key West, returning Tue, Nov 10, priced at $372 found 2 days ago
Tue, Oct 6 - Sat, Oct 10
STL
St. Louis
EYW
Key West
$384 Roundtrip, found 2 days ago
$384
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Oct 6 from St. Louis to Key West, returning Sat, Oct 10, priced at $384 found 2 days ago
Sat, Sep 19 - Wed, Sep 23
STL
St. Louis
EYW
Key West
$392 Roundtrip, found 5 days ago
$392
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Sep 19 from St. Louis to Key West, returning Wed, Sep 23, priced at $392 found 5 days ago
Sat, Oct 3 - Wed, Oct 7
STL
St. Louis
EYW
Key West
$395 Roundtrip, found 2 days ago
$395
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Oct 3 from St. Louis to Key West, returning Wed, Oct 7, priced at $395 found 2 days ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West

3.5 out of 5
3675 South Roosevelt Boulevard Key West FL
$226 nightly
The price is $255 total per night from Sep 2 to Sep 3
$255 total
Sep 2 - Sep 3
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,220 reviews)
"Very pretty landscaping, staff were very nice and helpful. Our family would stay again. Right beside airport was did not a bother us!"

Reviewed on Aug 8, 2026

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$148 nightly
The price is $166 total per night from Aug 30 to Aug 31
$166 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$149 nightly
The price is $168 total per night from Aug 16 to Aug 17
$168 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$203 nightly
The price is $228 total per night from Sep 1 to Sep 2
$228 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Southernmost Beach Resort and Guesthouses
Beachside Resort & Residences

Beachside Resort & Residences

3.5 out of 5
3841 N Roosevelt Blvd Key West FL
$192 nightly
The price is $216 total per night from Aug 10 to Aug 11
$216 total
Aug 10 - Aug 11
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
Beachside Resort & Residences
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$171 nightly
The price is $192 total per night from Sep 7 to Sep 8
$192 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
$149 nightly
The price is $168 total per night from Aug 16 to Aug 17
$168 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL

Hampton Inn Key West FL

2.5 out of 5
3755 S Roosevelt Blvd Key West FL
$148 nightly
The price is $166 total per night from Aug 30 to Aug 31
$166 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
Hampton Inn Key West FL
Eden House

Eden House

4 out of 5
1015 Fleming St Key West FL
$145 nightly
The price is $163 total per night from Aug 24 to Aug 25
$163 total
Aug 24 - Aug 25
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,011 reviews)
"Beautiful property. Staff were very friendly and helpful. Parking is limited which was the only downfall. Would definitely recommend and would book again"

Reviewed on Aug 8, 2026

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
$155 nightly
The price is $175 total per night from Aug 24 to Aug 25
$175 total
Aug 24 - Aug 25
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,371 reviews)
"Old School Cool! Great location and close to many amenities including golf cart rental! Air con was amazing. The bar table area was very useful. Larger TV would have been great!"

Reviewed on Aug 8, 2026

Southwinds Motel
Seashell Motel

Seashell Motel

1.5 out of 5
718 South Street Key West FL
$104 nightly
The price is $117 total per night from Aug 12 to Aug 13
$117 total
Aug 12 - Aug 13
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,004 reviews)
"Well the room was updated however no firealarm and wires were hanging out of th wall. Next room was very loud til 2am and staff wouldnt do anything about it. Pool was under maintenance for over weeks and closed to guests even though at booking nothing was mentioned about it."

Reviewed on Aug 7, 2026

Seashell Motel
Duval House

Duval House

3 out of 5
815 Duval St Key West FL
$131 nightly
The price is $144 total per night from Aug 10 to Aug 11
$144 total
Aug 10 - Aug 11
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
$203 nightly
The price is $228 total per night from Sep 1 to Sep 2
$228 total
Sep 1 - Sep 2
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
$171 nightly
The price is $192 total per night from Sep 7 to Sep 8
$192 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
Blue Flamingo Resort Key West
Hilton Key West Resort & Marina

Hilton Key West Resort & Marina

4 out of 5
5950 Peninsular Avenue Key West FL
$175 nightly
The price is $197 total per night from Aug 16 to Aug 17
$197 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular ...
Hilton Key West Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

STL to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from Lambert Field to Key West Intl. Airport?
You're going to need to switch planes if you're wanting to fly from STL to Key West Intl. Airport. A range of companies offer services on this route with only one stopover, including American Airlines, United Airlines and Delta Air Lines.
What is the shortest flight from St. Louis Lambert International Airport to Key West Intl. Airport (EYW)?
The shortest flight from STL to EYW is 5 hours and 10 minutes. Pack a few things in your carry-on to keep you amused, like a magazine or a crossword puzzle.
How many hours flight from St. Louis Lambert International Airport to EYW?
Typically, it takes 5 hours and 15 minutes to fly from STL to EYW. Get through this medium-haul journey by watching movies and getting stuck into a good book. Alternatively, squeeze in a bit of shut-eye.
What airlines have the most flights from St. Louis Lambert International Airport to EYW?
Do some people-watching, pick up a doughnut, get the blood pumping again .... Airport stopovers don't have to be something to dread! If you're traveling between St. Louis and Key West, you won't find any direct flights. Prepare to make a stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.