Cheap flights from STL to EYW (Lambert-St. Louis Intl. to Key West Intl.)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Cheap Flights from STL to EYW starting at $325 One Way, $293 Round Trip
Prices starting at $293 for return flights and $325 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
STL
St. Louis
EYW
Key West
$293 Roundtrip, found 3 days ago
$293
Roundtrip
found 3 days ago
STL
St. Louis
EYW
Key West
$300 Roundtrip, found 4 days ago
$300
Roundtrip
found 4 days ago
STL
St. Louis
EYW
Key West
$326 Roundtrip, found 3 days ago
$326
Roundtrip
found 3 days ago
STL
St. Louis
EYW
Key West
$333 Roundtrip, found 4 days ago
$333
Roundtrip
found 4 days ago
STL
St. Louis
EYW
Key West
$359 Roundtrip, found 3 days ago
$359
Roundtrip
found 3 days ago
Hotel Ideas near Key West Intl.
Airport Hotels near Key West Intl.
Hyatt Vacation Club at Windward Pointe, Key West
3675 South Roosevelt Boulevard Key West FL
$392 nightly
The price is $441 total per night from Jul 5 to Jul 6
$441 total
Jul 5 - Jul 6
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,157 reviews)
"Clean. Nice sized bedrooms. Plenty of space for family. Kitchen has everything needed to prepare a quick meal. Washer and dryer inside unit."
Reviewed on Jun 27, 2026
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$197 nightly
The price is $222 total per night from Jul 8 to Jul 9
$222 total
Jul 8 - Jul 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,403 reviews)
"It is a wonderful property. Not close to Old Town but the hotel offers a free shuttle so that was wonderful but we loved the location and the property. Will stay there when we return."
Reviewed on Jun 27, 2026
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$169 nightly
The price is $190 total per night from Jul 5 to Jul 6
$190 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,044 reviews)
"We loved staying in New Town and enjoyed the shuttle service back and forth to Old Town"
Reviewed on Jun 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Key West
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Jun 28 to Jun 29
$197 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,452 reviews)
"This was such a fun place! It was hard to leave to go touring because there was the huge beautiful pool out our door, also yard games outside all day, foosball and pool and other games. We enjoyed doing many of the activities in the evenings, even got to the karaoke airstream! The staff is available ..."
Reviewed on Jun 27, 2026
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$254 nightly
The price is $286 total per night from Jul 6 to Jul 7
$286 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,402 reviews)
"Love it !"
Reviewed on Jun 26, 2026
Hilton Garden Inn Key West / The Keys Collection
3850 N Roosevelt Blvd Key West FL
$140 nightly
The price is $158 total per night from Jul 5 to Jul 6
$158 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy 2 restaurants, breakfast (surcharge), and a free area shuttle. Our guests praise the pool and ...
8/10 Very Good! (1,250 reviews)
"This property is write down and was traditionally over priced for the stay. The gives run down Dexter vibes and was less than fabulous in its remodeling. One sad elevator and just a general sad run down hotel that might have been nice several decades ago even with the location. Parking was 100% full ..."
Reviewed on Jun 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Key West Hotels With Airport Transportation
DoubleTree Resort by Hilton Grand Key - Key West
3990 S Roosevelt Blvd Key West FL
$169 nightly
The price is $190 total per night from Jul 5 to Jul 6
$190 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,044 reviews)
"We loved staying in New Town and enjoyed the shuttle service back and forth to Old Town"
Reviewed on Jun 26, 2026
Hampton Inn Key West FL
3755 S Roosevelt Blvd Key West FL
$197 nightly
The price is $222 total per night from Jul 8 to Jul 9
$222 total
Jul 8 - Jul 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,403 reviews)
"It is a wonderful property. Not close to Old Town but the hotel offers a free shuttle so that was wonderful but we loved the location and the property. Will stay there when we return."
Reviewed on Jun 27, 2026
Eden House
1015 Fleming St Key West FL
$148 nightly
The price is $166 total per night from Jun 28 to Jun 29
$166 total
Jun 28 - Jun 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,004 reviews)
"I had a beautiful stay at Eden House. Room 221 was perfect for my needs. The staff was friendly and helpful at all times. If I had one tiny issue was the AC units are loud but it did not stop me from sleeping. For a home over 100 years old the upgrades are great. I will definitely suggest Eden House ..."
Reviewed on Jun 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Key West Hotels
Southwinds Motel
1321 Simonton Street Key West FL
$175 nightly
The price is $196 total per night from Jun 28 to Jun 29
$196 total
Jun 28 - Jun 29
Total with taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,342 reviews)
"Great place to stay because you are close to everything. Walls are thin so it can get loud. Good breakfast, great pool and super helpful staff."
Reviewed on Jun 26, 2026
Seashell Motel
718 South Street Key West FL
$131 nightly
The price is $147 total per night from Jun 28 to Jun 29
$147 total
Jun 28 - Jun 29
Total with taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8/10 Very Good! (1,000 reviews)
"Loved the close proximity to walk to the popular Duvall street for shopping and dining. The bathroom was huge!! Upgraded bathroom fixtures and tile. Great water pressure. Adjustable temperature A/C unit which was cold that I chose to turn up. Comfortable plush mattress, though the bed squeaked a ..."
Reviewed on Jun 8, 2026
Duval House
815 Duval St Key West FL
$116 nightly
The price is $128 total per night from Jul 1 to Jul 2
$128 total
Jul 1 - Jul 2
Total with taxes and fees
Stay at this B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,043 reviews)
"The property is a nice hotel however it needs some improvements … mostly the grounds are very nicely maintained but the decking on most area is filthy"
Reviewed on Jun 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Key West
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
$254 nightly
The price is $286 total per night from Jul 6 to Jul 7
$286 total
Jul 6 - Jul 7
Total with taxes and fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,402 reviews)
"Love it !"
Reviewed on Jun 26, 2026
Margaritaville Beach House Key West
2001 South Roosevelt Blvd Key West FL
Book a stay at this beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Southernmost Point and Duval Street ...
8.4/10 Very Good! (999 reviews)
Families like: Outdoor pool, babysitting, close to beach, bicycle rentals
Travelers say...
"This is a beautiful resort full of amenities! Margaritas when you arrive, smoothies at the pool each day around noon, free airport and old town shuttles so we didn’t need to Uber anywhere, also coffee/water/cookies in the lobby daily. The beach is an easy walk across the street. The hotel is super ..."
Reviewed on Apr 19, 2026
Blue Flamingo Resort Key West
3820 North Roosevelt Boulevard Key West FL
$175 nightly
The price is $197 total per night from Jun 28 to Jun 29
$197 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,452 reviews)
Families like: Outdoor pools, playground, miniature golf, game room
Travelers say...
"This was such a fun place! It was hard to leave to go touring because there was the huge beautiful pool out our door, also yard games outside all day, foosball and pool and other games. We enjoyed doing many of the activities in the evenings, even got to the karaoke airstream! The staff is available ..."
Reviewed on Jun 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
STL to EYW Route Info
Origin Airport | |
|---|---|
Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
- Airport Locations
- More Popular Flights
- Top Trending
- Flights from Other Cities
- Flights From Other Airports
- Great Travel Ideas
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York
Other Flights from Lambert-St. Louis Intl. Airport (STL)
Other Flights to Key West Intl. Airport (EYW)
- Abraham Lincoln Capital Airport (SPI)
- Quincy Regional-Baldwin Field Airport (UIN)
- Columbia Regional Airport (COU)
- Veterans Airport of Southern Illinois Airport (MWA)
- Decatur Airport (DEC)
- Cape Girardeau Municipal Airport (CGI)
- St. Robert Regional Airport (TBN)
- Cairo Regional Airport (CIR)
- Greater Peoria Regional Airport (PIA)
- Central Illinois Regional Airport (BMI)
Top Trending
Flights
- DCA to MCO
- BOS to MCO
- BDL to MCO
- LGA to MIA
- JFK to LAS
- LGA to FLL
- MCO to LAX
- DTW to MCO
- DCA to MIA
- LAX to DFW
- MCO to LGA
- SEA to SAN
- BWI to MIA
- JFK to FLL
- BWI to DFW
- LAX to MCO
- EWR to MCO
- SNA to LAS
- LGA to MCO
- MCO to JFK
- MCO to EWR
- ORD to MCO
- MCO to SJU
- PHL to MCO
- BWI to MCO
- JFK to MCO
- JFK to MIA
- DFW to CDG
- RDU to MCO
- DCA to BOS
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.