Cheap flights from RSW to SAN (Southwest Florida Intl. to San Diego Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from RSW to SAN starting at $178 One Way, $351 Round Trip

Prices starting at $351 for return flights and $178 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Sep 18 - Mon, Sep 21
RSW
Fort Myers
SAN
San Diego
$351 Roundtrip, found 4 days ago
$351
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Fri, Sep 18 from Fort Myers to San Diego, returning Mon, Sep 21, priced at $351 found 4 days ago
Thu, Sep 10 - Sun, Sep 13
RSW
Fort Myers
SAN
San Diego
$359 Roundtrip, found 6 days ago
$359
Roundtrip
found 6 days ago
Select JetBlue Airways flight, departing Thu, Sep 10 from Fort Myers to San Diego, returning Sun, Sep 13, priced at $359 found 6 days ago
Wed, Nov 18 - Wed, Dec 2
RSW
Fort Myers
SAN
San Diego
$366 Roundtrip, found 23 hours ago
$366
Roundtrip
found 23 hours ago
Select United flight, departing Wed, Nov 18 from Fort Myers to San Diego, returning Wed, Dec 2, priced at $366 found 23 hours ago
Wed, Nov 18 - Wed, Dec 2
RSW
Fort Myers
SAN
San Diego
$371 Roundtrip, found 23 hours ago
$371
Roundtrip
found 23 hours ago
Select Southwest Airlines flight, departing Wed, Nov 18 from Fort Myers to San Diego, returning Wed, Dec 2, priced at $371 found 23 hours ago
Wed, Nov 18 - Wed, Dec 2
RSW
Fort Myers
SAN
San Diego
$371 Roundtrip, found 23 hours ago
$371
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Nov 18 from Fort Myers to San Diego, returning Wed, Dec 2, priced at $371 found 23 hours ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Aug 12 to Aug 13
$245 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,599 reviews)
"Overprice"

Reviewed on Jul 19, 2026

Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Jul 28 to Jul 29
$211 total
Jul 28 - Jul 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd San Diego CA
$132 nightly
The price is $152 total per night from Aug 3 to Aug 4
$152 total
Aug 3 - Aug 4
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy parking (surcharge), a 24-hour front desk, and a business center. Our guests praise the helpful ...
7.4/10 Good! (4,156 reviews)
"Clean room"

Reviewed on Jul 19, 2026

Wyndham Garden San Diego Near SeaWorld
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
$311 nightly
The price is $358 total per night from Aug 16 to Aug 17
$358 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,733 reviews)
"Great and friendly staff loved the property and highly will revisit. The food was great at the tidal restaurant and had a lovely dinner. We were able to catch the sea world drone show at 845pm from the beach and it was amazing. The team was great they were super attentive and texted us for anything ..."

Reviewed on Jul 19, 2026

Paradise Point Resort & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Jul 28 to Jul 29
$211 total
Jul 28 - Jul 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
$229 nightly
The price is $265 total per night from Jul 27 to Jul 28
$265 total
Jul 27 - Jul 28
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Jul 28 to Jul 29
$211 total
Jul 28 - Jul 29
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$213 nightly
The price is $245 total per night from Aug 12 to Aug 13
$245 total
Aug 12 - Aug 13
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (3,599 reviews)
"Overprice"

Reviewed on Jul 19, 2026

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$168 nightly
The price is $193 total per night from Aug 16 to Aug 17
$193 total
Aug 16 - Aug 17
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,074 reviews)
"I didn't know there was a parking fee at the end but other than everything was good."

Reviewed on Jul 19, 2026

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$110 nightly
The price is $126 total per night from Aug 9 to Aug 10
$126 total
Aug 9 - Aug 10
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$78 nightly
The price is $90 total per night from Jul 21 to Jul 22
$90 total
Jul 21 - Jul 22
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.6/10 (2,141 reviews)
"Bed sunk in the middle and toilet was very low to the floor. Streets through the motel are very narrow and almost all parking spaces have hills going up making it dangerous to back out due to small streets. No plugs by either of the bedside stands for plufmgging in phones or medical equipment."

Reviewed on Jul 19, 2026

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$137 nightly
The price is $157 total per night from Aug 20 to Aug 21
$157 total
Aug 20 - Aug 21
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,736 reviews)
"Lo mejor de este hotel es la ubicación, céntrica y de fácil acceso. Limpio y cómodo."

Reviewed on Jul 19, 2026

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$296 nightly
The price is $340 total per night from Aug 19 to Aug 20
$340 total
Aug 19 - Aug 20
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,268 reviews)
"We discovered Bahia last summer when we dined at Bianchi for pizza & we knew we’d be back. This summer, we stayed at Bahia & it lived up to everything we expected. Our room was perfect for our family of 3 - separate bedroom for my husband & I & a comfortable fold out couch in the living room for ..."

Reviewed on Jul 19, 2026

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$254 nightly
The price is $292 total per night from Aug 16 to Aug 17
$292 total
Aug 16 - Aug 17
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,415 reviews)
"Just a little overpriced, definitely not a “resort” like advertised. But staff is super nice and helpful."

Reviewed on Jul 19, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$311 nightly
The price is $358 total per night from Aug 19 to Aug 20
$358 total
Aug 19 - Aug 20
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,316 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"Excellent facility. Didn’t get to see much of San Diego because we enjoyed the hotel so much."

Reviewed on Jul 18, 2026

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

RSW to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
RSW Address & GPS
Address:
11000 Terminal Access Road
Fort Myers FL,
United States
IATA Code:
RSW
Longitude:
-81.755263
Latitude:
26.527887
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Southwest Florida Intl. Airport (RSW) to San Diego Airport?
Unfortunately, nonstop flights aren't an option when traveling from Southwest Florida Intl. Airport (RSW) to San Diego Airport. However, there are a range of carriers that operate on this route with only one stopover, including Southwest Airlines, United Airlines and Delta Air Lines.
What is the shortest flight from Southwest Florida Intl. Airport to San Diego Intl. Airport (SAN)?
Jetting from RSW to SAN will take you at least 7 hours and 49 minutes. Savor a wine and watch a movie or two — now's your chance to relax.
How many hours flight from Southwest Florida Intl. Airport (RSW) to San Diego Airport?
Get comfortable, because a typical plane ride from Southwest Florida Intl. Airport (RSW) to San Diego Intl. Airport (SAN) is 7 hours and 54 minutes. Listen to a few podcasts, finish that book … There's plenty of time to kick back and relax.
What airlines have the most flights from Southwest Florida Intl. Airport (RSW) to San Diego Airport?
You'll have to make at least one stopover if you're planning to fly from Southwest Florida Intl. Airport (RSW) to San Diego Intl. Airport (SAN). For now, you won't find any airlines that advertise nonstop flights on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore