Cheap flights from GSP to SAN (Greenville-Spartanburg Intl. to San Diego Intl.)

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Cheap Flights from GSP to SAN starting at $154 One Way, $307 Round Trip

Prices starting at $307 for return flights and $154 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Feb 14 - Wed, Feb 18
GSP
Greenville
SAN
San Diego
$307 Roundtrip, found 2 days ago
$307
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Feb 14 from Greenville to San Diego, returning Wed, Feb 18, priced at $307 found 2 days ago
Wed, Feb 18 - Tue, Feb 24
GSP
Greenville
SAN
San Diego
$324 Roundtrip, found 4 days ago
$324
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Feb 18 from Greenville to San Diego, returning Tue, Feb 24, priced at $324 found 4 days ago
Wed, Feb 18 - Tue, Feb 24
GSP
Greenville
SAN
San Diego
$335 Roundtrip, found 4 days ago
$335
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Feb 18 from Greenville to San Diego, returning Tue, Feb 24, priced at $335 found 4 days ago
Wed, Feb 18 - Tue, Feb 24
GSP
Greenville
SAN
San Diego
$335 Roundtrip, found 4 days ago
$335
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Feb 18 from Greenville to San Diego, returning Tue, Feb 24, priced at $335 found 4 days ago
Wed, Feb 18 - Tue, Feb 24
GSP
Greenville
SAN
San Diego
$337 Roundtrip, found 4 days ago
$337
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Feb 18 from Greenville to San Diego, returning Tue, Feb 24, priced at $337 found 4 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$156 nightly
The price is $180 total per night from Dec 24 to Dec 25
$180 total
Dec 24 - Dec 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (3,173 reviews)
We did not have a coffee maker in our room. We called and requested one. It was brought to our room fifteen minutes later. Once we figured out which outlet worked, we had coffee and tea on our balcony. Super! Perhaps you might check the electrical in room 554?

Reviewed on Dec 22, 2025

Sheraton San Diego Resort
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$129 nightly
The price is $148 total per night from Jan 4 to Jan 5
$148 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9/10 Wonderful! (3,201 reviews)
Friendly staff. Awesome view of the bay

Reviewed on Dec 20, 2025

Bay Club Hotel & Marina
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
$112 nightly
The price is $130 total per night from Jan 4 to Jan 5
$130 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (781 reviews)
Nice and spacious

Reviewed on Dec 23, 2025

The DEXTRO Little Italy, BW Premier Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$156 nightly
The price is $180 total per night from Dec 24 to Dec 25
$180 total
Dec 24 - Dec 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (3,173 reviews)
We did not have a coffee maker in our room. We called and requested one. It was brought to our room fifteen minutes later. Once we figured out which outlet worked, we had coffee and tea on our balcony. Super! Perhaps you might check the electrical in room 554?

Reviewed on Dec 22, 2025

Sheraton San Diego Resort
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$129 nightly
The price is $148 total per night from Jan 4 to Jan 5
$148 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9/10 Wonderful! (3,201 reviews)
Friendly staff. Awesome view of the bay

Reviewed on Dec 20, 2025

Bay Club Hotel & Marina
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
$112 nightly
The price is $130 total per night from Jan 4 to Jan 5
$130 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (781 reviews)
Nice and spacious

Reviewed on Dec 23, 2025

The DEXTRO Little Italy, BW Premier Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$160 nightly
The price is $186 total per night from Dec 25 to Dec 26
$186 total
Dec 25 - Dec 26
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,014 reviews)
Loved the size of the room

Reviewed on Dec 23, 2025

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$156 nightly
The price is $180 total per night from Dec 24 to Dec 25
$180 total
Dec 24 - Dec 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (3,173 reviews)
We did not have a coffee maker in our room. We called and requested one. It was brought to our room fifteen minutes later. Once we figured out which outlet worked, we had coffee and tea on our balcony. Super! Perhaps you might check the electrical in room 554?

Reviewed on Dec 22, 2025

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$136 nightly
The price is $156 total per night from Dec 26 to Dec 27
$156 total
Dec 26 - Dec 27
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,041 reviews)
Such a friendly staff and so convenient!

Reviewed on Dec 18, 2025

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$83 nightly
The price is $95 total per night from Dec 31 to Jan 1
$95 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.4/10 Very Good! (1,283 reviews)
Clean rooms and reasonable rates- my home away from home in San Diego

Reviewed on Dec 18, 2025

Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$56 nightly
The price is $64 total per night from Dec 24 to Dec 25
$64 total
Dec 24 - Dec 25
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.4/10 (2,077 reviews)
Top notch customer service. Great place to stay. Central to everything worth seeing or doing in San Diego. Clean and comfortable beds hot shower cable tv. Refrigerator what else could you ask for at such an amazing price. Us as thr customer are definitely coming out on top

Reviewed on Dec 20, 2025

E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$82 nightly
The price is $94 total per night from Jan 7 to Jan 8
$94 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.8/10 Excellent! (3,567 reviews)
It almost reminded me of being in Catalina Island, older property, it was decorated super cute during the holidays. I wonder what it looks like on non-holiday season.

Reviewed on Dec 18, 2025

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$175 nightly
The price is $201 total per night from Jan 4 to Jan 5
$201 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.6/10 Excellent! (1,810 reviews)
Friendly staff and beautiful property

Reviewed on Dec 15, 2025

Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$156 nightly
The price is $180 total per night from Jan 4 to Jan 5
$180 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
8.8/10 Excellent! (3,935 reviews)
The staff was very nice, the room was very clean and we loved the marina view! The movie night at the pool was my daughter’s favorite part.

Reviewed on Dec 21, 2025

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$198 nightly
The price is $228 total per night from Jan 6 to Jan 7
$228 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,111 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
Great staff and clean

Reviewed on Dec 17, 2025

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

GSP to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Roger Milliken Field to San Diego Intl. Airport (SAN)?
Direct flights aren't an option when it comes to traveling from Roger Milliken Field to SAN. However, there are plenty of airlines that service this route with only one easy stopover, including American Airlines, United Airlines and Delta Air Lines.
What is the shortest flight from GSP to SAN?
The fastest you can fly from GSP to San Diego Intl. Airport (SAN) is 6 hours and 51 minutes. Slip a few things into your hand luggage to keep you occupied, like a gripping read or a portable board game.
How many hours flight from Roger Milliken Field to San Diego Intl. Airport (SAN)?
On average, it takes 6 hours and 57 minutes to travel from GSP to San Diego Airport. You'll be on board for a while, so think about bringing plenty of entertainment, like a good read or a podcast.
What airlines have the most flights from Greenville-Spartanburg Intl. Airport (GSP) to San Diego Airport?
There are no airlines that fly direct between Roger Milliken Field and San Diego Airport. Do your research and secure a multi or single-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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