Cheap flights from GSP to SAN (Greenville-Spartanburg Intl. to San Diego Intl.)

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Cheap Flights from GSP to SAN starting at $133 One Way, $265 Round Trip

Prices starting at $265 for return flights and $133 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Nov 17 - Wed, Nov 18
GSP
Greenville
SAN
San Diego
$265 Roundtrip, found 5 hours ago
$265
Roundtrip
found 5 hours ago
Select United flight, departing Tue, Nov 17 from Greenville to San Diego, returning Wed, Nov 18, priced at $265 found 5 hours ago
Tue, Nov 17 - Wed, Nov 18
GSP
Greenville
SAN
San Diego
$265 Roundtrip, found 5 hours ago
$265
Roundtrip
found 5 hours ago
Select Southwest Airlines flight, departing Tue, Nov 17 from Greenville to San Diego, returning Wed, Nov 18, priced at $265 found 5 hours ago
Tue, Nov 17 - Wed, Nov 18
GSP
Greenville
SAN
San Diego
$270 Roundtrip, found 5 hours ago
$270
Roundtrip
found 5 hours ago
Select United flight, departing Tue, Nov 17 from Greenville to San Diego, returning Wed, Nov 18, priced at $270 found 5 hours ago
Tue, Nov 17 - Wed, Nov 18
GSP
Greenville
SAN
San Diego
$279 Roundtrip, found 5 hours ago
$279
Roundtrip
found 5 hours ago
Select United flight, departing Tue, Nov 17 from Greenville to San Diego, returning Wed, Nov 18, priced at $279 found 5 hours ago
Tue, Nov 17 - Wed, Nov 18
GSP
Greenville
SAN
San Diego
$281 Roundtrip, found 5 hours ago
$281
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Nov 17 from Greenville to San Diego, returning Wed, Nov 18, priced at $281 found 5 hours ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$160 nightly
The price is $184 total per night from Nov 22 to Nov 23
$184 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Nov 1 to Nov 2
$211 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,342 reviews)
"Great location, just right across the bay and restaurants, but that also meant a lot of noise from the cars, street vendors, airplanes, cruise ship horns, etc. The room itself is ok. The HAVC unit didn’t work — the room was freezing, so we tried to warm it up, but it didn’t not blow warm air. The ..."

Reviewed on Oct 28, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$97 nightly
The price is $112 total per night from Nov 1 to Nov 2
$112 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Nov 1 to Nov 2
$211 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,342 reviews)
"Great location, just right across the bay and restaurants, but that also meant a lot of noise from the cars, street vendors, airplanes, cruise ship horns, etc. The room itself is ok. The HAVC unit didn’t work — the room was freezing, so we tried to warm it up, but it didn’t not blow warm air. The ..."

Reviewed on Oct 28, 2026

Wyndham San Diego Bayside
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$97 nightly
The price is $112 total per night from Nov 1 to Nov 2
$112 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
$203 nightly
The price is $235 total per night from Nov 22 to Nov 23
$235 total
Nov 22 - Nov 23
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (4,561 reviews)
"The staff was very friendly and helpful."

Reviewed on Oct 28, 2026

Hard Rock Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
$182 nightly
The price is $211 total per night from Nov 1 to Nov 2
$211 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,342 reviews)
"Great location, just right across the bay and restaurants, but that also meant a lot of noise from the cars, street vendors, airplanes, cruise ship horns, etc. The room itself is ok. The HAVC unit didn’t work — the room was freezing, so we tried to warm it up, but it didn’t not blow warm air. The ..."

Reviewed on Oct 28, 2026

Wyndham San Diego Bayside
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
$160 nightly
The price is $184 total per night from Nov 22 to Nov 23
$184 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG

2.5 out of 5
1955 San Diego Ave San Diego CA
$136 nightly
The price is $156 total per night from Nov 1 to Nov 2
$156 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn

Pleasant Inn

2.5 out of 5
5550 Clairemont Mesa Blvd San Diego CA
$89 nightly
The price is $102 total per night from Nov 26 to Nov 27
$102 total
Nov 26 - Nov 27
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
Pleasant Inn
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

2.5 out of 5
4747 Pacific Highway San Diego CA
$62 nightly
The price is $71 total per night from Oct 29 to Oct 30
$71 total
Oct 29 - Oct 30
Total with taxes and fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
E-Z 8 Motel Old Town
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
$115 nightly
The price is $132 total per night from Nov 9 to Nov 10
$132 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
$226 nightly
The price is $254 total per night from Nov 3 to Nov 4
$254 total
Nov 3 - Nov 4
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free parking, a private beach, and a marina. Our guests praise the pool and the restaurant in our reviews. ...
Bahia Resort Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
$198 nightly
The price is $228 total per night from Nov 15 to Nov 16
$228 total
Nov 15 - Nov 16
Total with taxes and fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (4,485 reviews)
"Loved our stay at The Dana. It was our first and hopefully not our last"

Reviewed on Oct 28, 2026

The Dana on Mission Bay
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
3999 Mission Boulevard San Diego CA
$261 nightly
The price is $301 total per night from Nov 28 to Nov 29
$301 total
Nov 28 - Nov 29
Total with taxes and fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

GSP to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
GSP Address & GPS
Address:
2000 GPS Drive, Suite 1
Greenville SC, 29651-9202
United States
IATA Code:
GSP
Longitude:
-82.217053
Latitude:
34.890569
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Roger Milliken Field to San Diego Intl. Airport (SAN)?
Direct flights aren't an option when it comes to traveling from Roger Milliken Field to SAN. However, there are plenty of airlines that service this route with only one easy stopover, including American Airlines, United Airlines and Delta Air Lines.
What is the shortest flight from GSP to SAN?
The fastest you can fly from GSP to San Diego Intl. Airport (SAN) is 6 hours and 51 minutes. Slip a few things into your hand luggage to keep you occupied, like a gripping read or a portable board game.
How many hours flight from Roger Milliken Field to San Diego Intl. Airport (SAN)?
On average, it takes 6 hours and 57 minutes to travel from GSP to San Diego Airport. You'll be on board for a while, so think about bringing plenty of entertainment, like a good read or a podcast.
What airlines have the most flights from Greenville-Spartanburg Intl. Airport (GSP) to San Diego Airport?
There are no airlines that fly direct between Roger Milliken Field and San Diego Airport. Do your research and secure a multi or single-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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