Cheap flights from DTW to STL (Detroit Metropolitan Wayne County to Lambert-St. Louis Intl.)

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Cheap Flights from DTW to STL starting at $85 One Way, $160 Round Trip

Prices starting at $160 for return flights and $85 for one-way flights to Lambert-St. Louis Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Apr 10 - Sat, Apr 11
DTW
Detroit
STL
St. Louis
$160 Roundtrip, found 2 days ago
$160
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Apr 10 from Detroit to St. Louis, returning Sat, Apr 11, priced at $160 found 2 days ago
Thu, Apr 9 - Fri, Apr 10
DTW
Detroit
STL
St. Louis
$170 Roundtrip, found 1 day ago
$170
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Apr 9 from Detroit to St. Louis, returning Fri, Apr 10, priced at $170 found 1 day ago
Sun, Apr 26 - Wed, Apr 29
DTW
Detroit
STL
St. Louis
$172 Roundtrip, found 3 days ago
$172
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Apr 26 from Detroit to St. Louis, returning Wed, Apr 29, priced at $172 found 3 days ago
Wed, Apr 8 - Fri, Apr 10
DTW
Detroit
STL
St. Louis
$174 Roundtrip, found 1 day ago
$174
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Apr 8 from Detroit to St. Louis, returning Fri, Apr 10, priced at $174 found 1 day ago
Sun, Apr 12 - Thu, Apr 16
DTW
Detroit
STL
St. Louis
$175 Roundtrip, found 1 day ago
$175
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Apr 12 from Detroit to St. Louis, returning Thu, Apr 16, priced at $175 found 1 day ago

Hotel Ideas near Lambert-St. Louis Intl.

Airport Hotels near Lambert-St. Louis Intl.

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$88 nightly
The price is $104 total per night from Feb 24 to Feb 25
$104 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,824 reviews)
We have always received good service at this hotel. The bed is comfortable and the bedroom has a nice layout. The price beats all of the surrounding competition. But, the best part of this hotel is the outstanding breakfast!

Reviewed on Feb 17, 2026

Pear Tree Inn St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$118 nightly
The price is $141 total per night from Feb 26 to Feb 27
$141 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,002 reviews)
Clean and very close to airport.

Reviewed on Feb 13, 2026

Hilton St. Louis Airport
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

3 out of 5
10490 Natural Bridge Rd St. Louis MO
$107 nightly
The price is $126 total per night from Feb 26 to Feb 27
$126 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,133 reviews)
The room was clean

Reviewed on Feb 9, 2026

Drury Inn & Suites St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In St. Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
$131 nightly
The price is $153 total per night from Mar 15 to Mar 16
$153 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,609 reviews)
The bathtub wouldn't drain and the door handle was broke. Other than that - it was a great stay. Happy Hour was wonderful. Great burger and drinks.

Reviewed on Feb 15, 2026

21C Museum Hotel St Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$88 nightly
The price is $104 total per night from Feb 24 to Feb 25
$104 total
Feb 24 - Feb 25
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,824 reviews)
We have always received good service at this hotel. The bed is comfortable and the bedroom has a nice layout. The price beats all of the surrounding competition. But, the best part of this hotel is the outstanding breakfast!

Reviewed on Feb 17, 2026

Pear Tree Inn St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$102 nightly
The price is $119 total per night from Feb 22 to Feb 23
$119 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,088 reviews)
Room was nice felt like i was at home

Reviewed on Feb 15, 2026

Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis Hotels With Airport Transportation

Quality Inn St. Louis Airport Hotel

Quality Inn St. Louis Airport Hotel

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$57 nightly
The price is $67 total per night from Mar 3 to Mar 4
$67 total
Mar 3 - Mar 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,000 reviews)
Good

Reviewed on Feb 15, 2026

Quality Inn St. Louis Airport Hotel
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
$145 nightly
The price is $173 total per night from Feb 27 to Feb 28
$173 total
Feb 27 - Feb 28
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
7.8/10 Good! (1,002 reviews)
The staff was great and the hotel was beautiful for location. It looked well maintained.

Reviewed on Jan 11, 2026

Marriott St. Louis Airport
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
$118 nightly
The price is $141 total per night from Feb 26 to Feb 27
$141 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,002 reviews)
Clean and very close to airport.

Reviewed on Feb 13, 2026

Hilton St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced St. Louis Hotels

Quality Inn St. Louis Airport Hotel

Quality Inn St. Louis Airport Hotel

2.5 out of 5
10232 Natural Bridge Rd St. Louis MO
$57 nightly
The price is $67 total per night from Mar 3 to Mar 4
$67 total
Mar 3 - Mar 4
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a free airport shuttle, and parking (surcharge). Our guests praise the helpful staff ...
6.2/10 (1,000 reviews)
Good

Reviewed on Feb 15, 2026

Quality Inn St. Louis Airport Hotel
Americas Best Value Inn St. Louis Downtown

Americas Best Value Inn St. Louis Downtown

2 out of 5
1100 Lumiere Place Boulevard St. Louis MO
$79 nightly
The price is $92 total per night from Mar 2 to Mar 3
$92 total
Mar 2 - Mar 3
Total with taxes and fees
Stay at this motel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Gateway Arch and St. Louis Union Station are located ...
5.6/10 (828 reviews)
We needed a place near the convention center that wasn't crazy expensive. The worker and manager were both very friendly.

Reviewed on Dec 9, 2025

Americas Best Value Inn St. Louis Downtown
OYO Hotel St. Louis Downtown City Center MO

OYO Hotel St. Louis Downtown City Center MO

3.5 out of 5
400 S 14th St St. Louis MO
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
Definitely an older hotel. Overall the room was kinda dingy.

Reviewed on Apr 11, 2024

Get rates
OYO Hotel St. Louis Downtown City Center MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in St. Louis

Days Inn by Wyndham St. Louis Lindbergh Boulevard

Days Inn by Wyndham St. Louis Lindbergh Boulevard

2.5 out of 5
South Lindbergh Boulevard, 3660 St. Louis MO
Book a stay at this family-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a nightclub. Popular attractions Laumeier Sculpture Park and Magic ...
6.6/10 (1,000 reviews)

Families like: Indoor pool, playground, game room, cribs

Travelers say...
The Pool, and things for the kids to do was great.

Reviewed on Feb 18, 2021

Get rates
Days Inn by Wyndham St. Louis Lindbergh Boulevard
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$135 nightly
The price is $158 total per night from Feb 23 to Feb 24
$158 total
Feb 23 - Feb 24
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,321 reviews)
Everything

Reviewed on Feb 19, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
$92 nightly
The price is $108 total per night from Mar 5 to Mar 6
$108 total
Mar 5 - Mar 6
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,828 reviews)
great location and parking

Reviewed on Feb 16, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DTW to STL Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DTW Address & GPS
Address:
1 Detroit Metro Airport
Detroit MI, 48242
United States
IATA Code:
DTW
Longitude:
-83.356048
Latitude:
42.207808
Time Zone:
America/New_York
STL Address & GPS
Address:
10701 Lambert International Blvd.
Saint Louis MO, 63145
United States
IATA Code:
STL
Longitude:
-90.379002
Latitude:
38.748707
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from Metro Airport to STL?
If you're looking to travel from Metro Airport to Lambert Field as speedily as possible, we're happy to say that there are multiple airlines that operate nonstop flights. They include Delta Air Lines and Southwest Airlines.
What is the shortest flight from Detroit Metro Airport to St. Louis Lambert International Airport?
Few things are better than an impromptu getaway. And with the flight from Detroit to St. Louis being as quick as 1 hour and 40 minutes, you hardly have an excuse not to take one.
How many hours flight from Metro Airport to Lambert Field?
The typical flight time from DTW to STL is a short and sweet 1 hour and 50 minutes. So, toss a few things in your suitcase and book your seat. There's nothing more exciting than a spur-of-the-moment getaway.
What airlines have the most flights from Detroit Metro Airport to St. Louis Lambert International Airport?
Going on vacation is one of life's greatest pleasures, but how you arrive at your destination should be equally as enjoyable. Consider booking your DTW to Lambert-St. Louis Intl. Airport (STL) flight with Southwest Airlines (WN). One of the most popular airlines, it offers 58 flights each month on this route. Delta Air Lines (DL) also operates services from Detroit to St. Louis. It's another popular option and offers 121 flights every month.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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