$91 Cheap flight deals from Louisville (SDF) to Panama City (PNS)

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This Weekend's Flight Deals from Louisville to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Dec 27 - Wed, Dec 31
SDF
Louisville Intl.
PNS
Pensacola Intl.
$417 Roundtrip, found 4 days ago
$417
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Dec 27 from Louisville Intl. to Pensacola Intl., returning Wed, Dec 31, priced at $417 found 4 days ago
Sat, Dec 27 - Sat, Jan 17
SDF
Louisville Intl.
ECP
Northwest Florida Beaches Intl.
$506 Roundtrip, found 1 day ago
$506
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Dec 27 from Louisville Intl. to Northwest Florida Beaches Intl., returning Sat, Jan 17, priced at $506 found 1 day ago

Airfares from $91 One Way, $209 Round Trip from Louisville to Panama City

Prices starting at $209 for return flights and $91 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Feb 19 - Fri, Feb 27
SDF
Louisville
PNS
Pensacola
$209 Roundtrip, found 6 days ago
$209
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Thu, Feb 19 from Louisville to Pensacola, returning Fri, Feb 27, priced at $209 found 6 days ago
Mon, Feb 23 - Fri, Feb 27
SDF
Louisville
PNS
Pensacola
$217 Roundtrip, found 6 days ago
$217
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Mon, Feb 23 from Louisville to Pensacola, returning Fri, Feb 27, priced at $217 found 6 days ago
Wed, Apr 8 - Wed, Apr 15
SDF
Louisville
PNS
Pensacola
$222 Roundtrip, found 14 hours ago
$222
Roundtrip
found 14 hours ago
Select Spirit Airlines flight, departing Wed, Apr 8 from Louisville to Pensacola, returning Wed, Apr 15, priced at $222 found 14 hours ago
Thu, Mar 12 - Wed, Mar 18
LEX
Lexington
ECP
Panama City
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Mar 12 from Lexington to Panama City, returning Wed, Mar 18, priced at $269 found 1 day ago
Wed, Dec 31 - Thu, Jan 1
SDF
Louisville
PNS
Pensacola
$273 Roundtrip, found 4 days ago
$273
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 31 from Louisville to Pensacola, returning Thu, Jan 1, priced at $273 found 4 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Sandestin Golf and Beach Resort
4.0-star property

Sandestin Golf and Beach Resort

7.8/10 Good! (3,841 reviews)

Feb 15 - Feb 17

2 night stay

Louisville (SDF) to Fort Walton Beach (VPS)

Southwest Airlines • Non-stop • Coach

Fort Walton Beach (VPS) to Louisville (SDF)

Delta • Non-stop • Coach
Price was $583, price is now $485 per person
$485
per person
found 1 day ago
Motorcycle not welcome, front desk lady rude ,no housekeeping until 3 days 🙄 i request clean sheets never get it

Reviewed on Apr 28, 2025

El Matador
4.0-star property

El Matador

No reviews

Feb 18 - Feb 22

4 night stay

Louisville (SDF) to Pensacola (PNS)

Delta • Non-stop roundtrip • Coach
Price was $987, price is now $801 per person
$801
per person
found 3 hours ago
Landing Apartments - Freeport
4.0-star property

Landing Apartments - Freeport

No reviews

Feb 15 - Feb 17

2 night stay

Louisville (SDF) to Panama City (ECP)

Southwest Airlines • Non-stop • Coach

Panama City (ECP) to Louisville (SDF)

Delta • Non-stop • Coach
Price was $725, price is now $619 per person
$619
per person
found 1 day ago
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More About Flying To Panama City from Louisville

Route Information for Flights from Louisville to Panama City

Origin Airport IATA Code
SDF
Destination Airport IATA Code
PNS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Louisville to Panama City

If you are looking to find the best deals on Louisville to Panama City flights, look no further than Orbitz. Orbitz offers guaranteed low prices as well as cutting-edge mobile tools to help you book cheap flights from Louisville to Panama City.

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Orbitz keeps you updated on information that’s relevant to your flights from Louisville to Panama City. We can send you and six of your personal contacts free travel alerts via SMS text, voicemail, or email, so you instantly know about flight delays or changes.

Keep More Money in Your Pocket With Discount Flights

Orbitz looks for the best deals on Louisville to Panama City flights for you. Mix and match airlines for your departing and return flights to fit your travel schedule and budget.

Frequently asked questions

Are there non-stop flights from Louisville to Panama City?
Yes, you can fly from Louisville, KY (SDF-Louisville Intl.) to Destin–Fort Walton Beach Airport with Allegiant Air, the only airline offering nonstop services on this route.
What is the shortest flight from Louisville to Panama City?
The trip from Louisville to Panama City can be as quick as 2 hours and 23 minutes. With a leisurely flight time like this, why not round up some friends and take off on an impromptu getaway?
What airlines fly from Louisville to Panama City most frequently?
Allegiant Air is the most frequent flyer along this route. This trusted air carrier operates 17 flights from Louisville Intl. Airport (SDF) to Fort Walton Beach, FL (VPS-Northwest Florida Regional) every month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.