Hotels in Mayo Clinic

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Dec 16 - Dec 17
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Featured Hotels in Mayo Clinic

Talking Stick Resort

Talking Stick Resort

4 out of 5
9800 E. Talking Stick Way Scottsdale AZ
5.56 mi from Mayo Clinic
$184 nightly
The price is $210 total per night
$210 total
Dec 22 - Dec 23
Total with taxes and fees
Talking Stick Resort features a golf course, a full-service spa, and 2 outdoor pools. Free valet and self parking are available, and there's also limo/town car service. Multilingual staff at the 24-hour front desk can assist with concierge services, dry cleaning/laundry, and luggage storage. Other amenities at this spa resort include a casino, a 24-hour gym, and a steam room.
Pool
Spa
Scottsdale Plaza Resort

Scottsdale Plaza Resort

4 out of 5
7200 N Scottsdale Rd Paradise Valley AZ
Free Cancellation
8.4 mi from Mayo Clinic
$165 nightly
The price is $187 total per night
$187 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Scottsdale Plaza Resort & Villas (soon to be Kimpton) have access to a full-service spa, 3 outdoor pools, and a 24-hour gym. The front desk has multilingual staff on hand 24/7 to help with tours or tickets, luggage storage, and dry cleaning/laundry. Other amenities at this luxury resort include meeting rooms, coffee/tea in a common area, and a computer station.
Pool
Spa
Hotel Valley Ho

Hotel Valley Ho

4.5 out of 5
6850 E Main St Scottsdale AZ
Free Cancellation
Reserve now, pay when you stay
10.36 mi from Mayo Clinic
$235 nightly
The price is $268 total per night
$268 total
Dec 30 - Dec 31
Total with taxes and fees
Guests of Hotel Valley Ho have access to a full-service spa, 2 outdoor pools, and a 24-hour gym. Parking is available for USD 31.92 per day (USD 31.92 per day for valet parking), and there's also limo/town car service. The front desk has multilingual staff on hand 24/7 to help with concierge services, luggage storage, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury resort include a steam room, free WiFi in public areas, and a hot tub.
Pool
Hot Tub
Scottsdale Parkview Resort

Scottsdale Parkview Resort

3.5 out of 5
7707 E McDowell Rd Scottsdale AZ
Free Cancellation
Reserve now, pay when you stay
10.9 mi from Mayo Clinic
$78 nightly
The price is $89 total per night
$89 total
Dec 17 - Dec 18
Total with taxes and fees
Guests staying at Scottsdale Parkview Resort enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. Front-desk staff can assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub
Omni Scottsdale Resort & Spa at Montelucia

Omni Scottsdale Resort & Spa at Montelucia

4 out of 5
4949 E Lincoln Drive Paradise Valley AZ
Free Cancellation
Reserve now, pay when you stay
11.04 mi from Mayo Clinic
$282 nightly
The price is $319 total per night
$319 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Omni Scottsdale Resort & Spa at Montelucia have access to a full-service spa, 3 outdoor pools, and a 24-hour gym. Valet parking is available for USD 35 per night. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this spa resort include a sauna, free WiFi in public areas, and a hot tub.
Pool
Hot Tub
Arizona Biltmore, LXR Hotels & Resorts

Arizona Biltmore, LXR Hotels & Resorts

5 out of 5
2400 E Missouri Avenue Phoenix AZ
Free Cancellation
Reserve now, pay when you stay
13.96 mi from Mayo Clinic
$379 nightly
The price is $429 total per night
$429 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Arizona Biltmore, LXR Hotels & Resorts features a golf course, a full-service spa, and 7 outdoor pools. Parking is available for USD 28 per day (USD 35 per day for valet parking), and there's also limo/town car service. The 24-hour front desk has multilingual staff ready to assist with luggage storage, dry cleaning/laundry, and tours or tickets. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury resort include a 24-hour gym, 2 hot tubs, and meeting rooms.
Pool
Hot Tub
Hilton Phoenix Resort at the Peak

Hilton Phoenix Resort at the Peak

4 out of 5
7677 N 16th St Phoenix AZ
Free Cancellation
Reserve now, pay when you stay
14.84 mi from Mayo Clinic
$147 nightly
The price is $166 total per night
$166 total
Dec 21 - Dec 22
Total with taxes and fees
Hilton Phoenix Resort at the Peak features a full-service spa, 7 outdoor pools, and a free water park. If you drive, take advantage of free parking. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, luggage storage, and securing valuables. Other amenities at this spa resort include a lazy river, a children's pool, and a gym.
Pool
Hot Tub
Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North

3 out of 5
3838 E Van Buren St Phoenix AZ
Free Cancellation
Reserve now, pay when you stay
15.01 mi from Mayo Clinic
$86 nightly
The price is $97 total per night
$97 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Hilton Garden Inn Phoenix Airport North have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, self parking is USD 7 per day, or you can take advantage of the free airport shuttle (available 24 hours). The 24-hour front desk has staff standing by to help with luggage storage and tours/tickets. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free airport shuttle
Hilton Phoenix Tapatio Cliffs Resort

Hilton Phoenix Tapatio Cliffs Resort

4 out of 5
11111 N 7th St Phoenix AZ
Free Cancellation
Reserve now, pay when you stay
15.75 mi from Mayo Clinic
$145 nightly
The price is $164 total per night
$164 total
Dec 22 - Dec 23
Total with taxes and fees
Hilton Phoenix Tapatio Cliffs Resort features a golf course, a full-service spa, and 7 outdoor pools. Free valet and self parking are available, and there's also limo/town car service. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, luggage storage, and tours or tickets. Other amenities at this spa resort include a free water park, a 24-hour gym, and 7 hot tubs.
Pool
Hot Tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mayo Clinic Hotels

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Great selection of hotels in Mayo Clinic

Whether you're searching for hotels in Mayo Clinic on business, or hunting for a family getaway, Mayo Clinic hotel options are only a click away. Find hotels in Mayo Clinic with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Mayo Clinic hotels close you are to the airport and nearby attractions.

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Thanks to photos and virtual tours, you can look before you book your Mayo Clinic hotel reservation. Check out Mayo Clinic hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Mayo Clinic with unbiased reviews from verified Mayo Clinic hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

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On Orbitz, Mayo Clinic hotel deals mean flexibility. If you need to change your Mayo Clinic hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to Mayo Clinic all in one place.

 

Mayo Clinic hotels essential information

Accommodation
13,024 hotels
Lowest Price
$89
Highest Price
$429
Popular hotels
Talking Stick Resort, Hilton Phoenix Tapatio Cliffs Resort, Hilton Garden Inn Phoenix Airport North, Arizona Biltmore, LXR Hotels & Resorts, Omni Scottsdale Resort & Spa at Montelucia, Hotel Valley Ho, Scottsdale Plaza Resort, Scottsdale Parkview Resort, Hilton Phoenix Resort at the Peak

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Recent Reviews

Hotel Valley Ho

Hotel Valley Ho

5/5 Excellent
"Yes"
A verified traveler stayed at Hotel Valley Ho
Posted 15 hours ago
Hotel Valley Ho

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