Cheap flights from SNA to SDF (John Wayne to Louisville Intl.)

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Cheap Flights from SNA to SDF starting at $184 One Way, $437 Round Trip

Prices starting at $437 for return flights and $184 for one-way flights to Louisville Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Mar 26 - Tue, Mar 31
SNA
Orange County
SDF
Louisville
$437 Roundtrip, found 17 hours ago
$437
Roundtrip
found 17 hours ago
Select Delta flight, departing Thu, Mar 26 from Orange County to Louisville, returning Tue, Mar 31, priced at $437 found 17 hours ago
Sat, Jul 4 - Fri, Jul 10
SNA
Orange County
SDF
Louisville
$439 Roundtrip, found 11 hours ago
$439
Roundtrip
found 11 hours ago
Select Delta flight, departing Sat, Jul 4 from Orange County to Louisville, returning Fri, Jul 10, priced at $439 found 11 hours ago
Tue, Apr 7 - Sun, Apr 12
SNA
Orange County
SDF
Louisville
$449 Roundtrip, found 1 day ago
$449
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Apr 7 from Orange County to Louisville, returning Sun, Apr 12, priced at $449 found 1 day ago
Tue, Apr 7 - Sun, Apr 12
SNA
Orange County
SDF
Louisville
$455 Roundtrip, found 1 day ago
$455
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Tue, Apr 7 from Orange County to Louisville, returning Sun, Apr 12, priced at $455 found 1 day ago
Tue, Apr 7 - Sun, Apr 12
SNA
Orange County
SDF
Louisville
$457 Roundtrip, found 1 day ago
$457
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Apr 7 from Orange County to Louisville, returning Sun, Apr 12, priced at $457 found 1 day ago

Hotel Ideas near Louisville Intl.

Airport Hotels near Louisville Intl.

Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 out of 5
830 Phillips Lane Louisville KY
$97 nightly
The price is $114 total per night from Feb 1 to Feb 2
$114 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the ...
8.8/10 Excellent! (1,072 reviews)
Room was in good shape; though, you can not open windows. It has a refrigerator and coffee maker. Beds were perfect for my family. Staff was excellent and helped us when requested.

Reviewed on Dec 27, 2025

Crowne Plaza Louisville Airport Expo Ctr by IHG
Studio 6 Suites Louisville, KY – Airport/Expo Center

Studio 6 Suites Louisville, KY – Airport/Expo Center

2 out of 5
571 Phillips Ln Louisville KY
$59 nightly
The price is $69 total per night from Jan 3 to Jan 4
$69 total
Jan 3 - Jan 4
Total with taxes and fees
Stay at this hotel in Louisville. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in ...
7.2/10 Good! (521 reviews)
Interior was quite nice. Exterior was leas appealing. Staff was kind and courteous.

Reviewed on Dec 28, 2025

Studio 6 Suites Louisville, KY – Airport/Expo Center
Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport

3 out of 5
819 Phillips Lane Louisville KY
$107 nightly
The price is $126 total per night from Jan 5 to Jan 6
$126 total
Jan 5 - Jan 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (344 reviews)
Amenities, restaurants, location, room was nice

Reviewed on Dec 20, 2025

Courtyard by Marriott Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Louisville

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
$133 nightly
The price is $157 total per night from Jan 6 to Jan 7
$157 total
Jan 6 - Jan 7
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
8.8/10 Excellent! (3,915 reviews)
Beautiful hotel

Reviewed on Dec 30, 2025

Galt House Hotel Trademark Collection by Wyndham
Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 out of 5
830 Phillips Lane Louisville KY
$97 nightly
The price is $114 total per night from Feb 1 to Feb 2
$114 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the ...
8.8/10 Excellent! (1,072 reviews)
Room was in good shape; though, you can not open windows. It has a refrigerator and coffee maker. Beds were perfect for my family. Staff was excellent and helped us when requested.

Reviewed on Dec 27, 2025

Crowne Plaza Louisville Airport Expo Ctr by IHG
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
$167 nightly
The price is $197 total per night from Jan 4 to Jan 5
$197 total
Jan 4 - Jan 5
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,745 reviews)
Excellent friendly staff

Reviewed on Dec 19, 2025

Omni Louisville Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Louisville Hotels With Airport Transportation

The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
$168 nightly
The price is $198 total per night from Jan 3 to Jan 4
$198 total
Jan 3 - Jan 4
Total with taxes and fees
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,164 reviews)
Courteous staff, well-attended rooms, great amenities.

Reviewed on Dec 28, 2025

The Brown Hotel
Holiday Inn Express Louisville Airport Expo Center by IHG

Holiday Inn Express Louisville Airport Expo Center by IHG

2.5 out of 5
1921 Bishop Ln Louisville KY
$95 nightly
The price is $112 total per night from Jan 6 to Jan 7
$112 total
Jan 6 - Jan 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,004 reviews)
Great

Reviewed on Dec 27, 2025

Holiday Inn Express Louisville Airport Expo Center by IHG
Howard Johnson by Wyndham Airport

Howard Johnson by Wyndham Airport

2 out of 5
709 Phillips Lane Louisville KY
$140 nightly
The price is $162 total per night from Feb 1 to Feb 2
$162 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (999 reviews)
Great stay

Reviewed on Jan 28, 2025

Howard Johnson by Wyndham Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Louisville Hotels

Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown

2 out of 5
401 S 2nd St Louisville KY
$63 nightly
The price is $74 total per night from Jan 18 to Jan 19
$74 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly motel in Louisville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7/10 Good! (1,004 reviews)
Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again

Reviewed on Dec 11, 2025

Econo Lodge Louisville Downtown
Red Roof Inn Louisville Fair and Expo

Red Roof Inn Louisville Fair and Expo

2 out of 5
3322 Red Roof Inn Pl Louisville KY
$65 nightly
The price is $76 total per night from Jan 8 to Jan 9
$76 total
Jan 8 - Jan 9
Total with taxes and fees
Stay at this hotel in Louisville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,003 reviews)
Very clean and comfortable. Just didnt have a fridge or microwave. And i couldnt get the hairdryer to work. But overall a great stay. Felt safe. Parking was good.

Reviewed on Dec 22, 2025

Red Roof Inn Louisville Fair and Expo
Super 8 by Wyndham Louisville Airport

Super 8 by Wyndham Louisville Airport

2.5 out of 5
4800 Preston Hwy Louisville KY
$60 nightly
The price is $71 total per night from Jan 4 to Jan 5
$71 total
Jan 4 - Jan 5
Total with taxes and fees
Book a stay at this business-friendly motel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
4.6/10 (1,001 reviews)
Great clean affordable room

Reviewed on Dec 5, 2025

Super 8 by Wyndham Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Louisville

Drury Inn & Suites Louisville North

Drury Inn & Suites Louisville North

3 out of 5
9597 Brownsboro Road Louisville KY
$100 nightly
The price is $118 total per night from Jan 7 to Jan 8
$118 total
Jan 7 - Jan 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
The breakfast was yummy, I was able to fill up a plate and head back to my room to eat it. They were VERY friendly staff but not overly friendly, they truely wanted you to have a pleasant stay. I didn’t try the dinner here because there were so many steak houses near by, but the pop corn and soda ...

Reviewed on Dec 30, 2025

Drury Inn & Suites Louisville North
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
$133 nightly
The price is $157 total per night from Jan 6 to Jan 7
$157 total
Jan 6 - Jan 7
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
8.8/10 Excellent! (3,915 reviews)
Beautiful hotel

Reviewed on Dec 30, 2025

Galt House Hotel Trademark Collection by Wyndham
Country Inn & Suites by Radisson, Louisville South, KY

Country Inn & Suites by Radisson, Louisville South, KY

2 out of 5
400 Paroquet Springs Drive Shepherdsville KY
$86 nightly
The price is $96 total per night from Jan 4 to Jan 5
$96 total
Jan 4 - Jan 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Shepherdsville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
7.8/10 Good! (1,000 reviews)
Excellent stop on journey south. It’s clean, functional and modern. We love the suite style. Very reasonably priced. Breakfast is as to be expected- very few edible things for healthy eaters- overcooked scrambled eggs, Raisin Bran with raisins so hard you would crack teeth.

Reviewed on Dec 12, 2025

Country Inn & Suites by Radisson, Louisville South, KY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SNA to SDF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from SNA to Louisville Intl. Airport (SDF)?
While you won't be able to fly directly from John Wayne Airport to Louisville Intl. Airport (SDF), there are several airlines that operate on this route with just one stop. Why not find out if the dates and times offered by United Airlines or American Airlines work with your travel plans? If not, take a look at Southwest Airlines.
What is the shortest flight from John Wayne Airport to Louisville Muhammad Ali Intl. Airport?
Ask for a glass of red and get comfortable in your seat with a riveting movie or book. With the journey from John Wayne Airport to Louisville Intl. Airport (SDF) taking 5 hours and 21 minutes, you'll have enough time to sit back and enjoy the experience.
How many hours flight from John Wayne Airport to Louisville Intl. Airport (SDF)?
From John Wayne Airport (SNA) to SDF, you'll be traveling for about 5 hours and 28 minutes. Get comfy, grab a wine and take out your noise-canceling headphones. It's time for a movie marathon.
What airlines have the most flights from SNA to Louisville Muhammad Ali Intl. Airport?
Indulge in some people-watching, grab a quick meal, get the blood flowing again ... Airport stopovers don't have to be annoying! If you're planning to head from John Wayne Airport to SDF, you can't fly direct. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.