Cheap flights from SNA to BUF (John Wayne to Buffalo Niagara Intl.)

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Cheap Flights from SNA to BUF starting at $193 One Way, $357 Round Trip

Prices starting at $357 for return flights and $193 for one-way flights to Buffalo Niagara Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jan 20 - Tue, Feb 3
SNA
Orange County
BUF
Buffalo
$357 Roundtrip, found 3 days ago
$357
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jan 20 from Orange County to Buffalo, returning Tue, Feb 3, priced at $357 found 3 days ago
Tue, Jan 20 - Tue, Feb 3
SNA
Orange County
BUF
Buffalo
$363 Roundtrip, found 3 days ago
$363
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jan 20 from Orange County to Buffalo, returning Tue, Feb 3, priced at $363 found 3 days ago
Tue, Jan 20 - Sat, Jan 31
SNA
Orange County
BUF
Buffalo
$381 Roundtrip, found 3 days ago
$381
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Jan 20 from Orange County to Buffalo, returning Sat, Jan 31, priced at $381 found 3 days ago
Tue, Jan 20 - Fri, Feb 6
SNA
Orange County
BUF
Buffalo
$391 Roundtrip, found 3 days ago
$391
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Jan 20 from Orange County to Buffalo, returning Fri, Feb 6, priced at $391 found 3 days ago
Wed, Jan 21 - Wed, Feb 4
SNA
Orange County
BUF
Buffalo
$392 Roundtrip, found 3 days ago
$392
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Jan 21 from Orange County to Buffalo, returning Wed, Feb 4, priced at $392 found 3 days ago

Hotel Ideas near Buffalo Niagara Intl.

Airport Hotels near Buffalo Niagara Intl.

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
$89 nightly
The price is $101 total per night from Dec 21 to Dec 22
$101 total
Dec 21 - Dec 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
7.8/10 Good! (2,784 reviews)
Clean room and desk staff was great

Reviewed on Dec 19, 2025

Buffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
$84 nightly
The price is $96 total per night from Jan 8 to Jan 9
$96 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,900 reviews)
Seamless and easy check-in and check-out. Except I had to get my card re-activated EVERYDAY because it stopped working EVERYDAY 😡 that was annoying. The jacuzzi room was spacious but the king bed was old and worn out. It sunk in when you laid on it. Breakfast was good. Staff was friendly

Reviewed on Dec 16, 2025

Sleep Inn & Suites Buffalo Airport
Hilton Garden Inn Buffalo Airport

Hilton Garden Inn Buffalo Airport

3 out of 5
4201 Genesee St Buffalo NY
$128 nightly
The price is $145 total per night from Dec 25 to Dec 26
$145 total
Dec 25 - Dec 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,002 reviews)
Room was very clean and staff at check in was friendly.

Reviewed on Dec 17, 2025

Hilton Garden Inn Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Buffalo

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
$99 nightly
The price is $113 total per night from Dec 21 to Dec 22
$113 total
Dec 21 - Dec 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
7.2/10 Good! (2,528 reviews)
Clean room, pleasant staff, room was larger than expected

Reviewed on Dec 16, 2025

M Hotel Buffalo
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
$89 nightly
The price is $101 total per night from Dec 21 to Dec 22
$101 total
Dec 21 - Dec 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
7.8/10 Good! (2,784 reviews)
Clean room and desk staff was great

Reviewed on Dec 19, 2025

Buffalo Airport Hotel
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
$89 nightly
The price is $101 total per night from Dec 22 to Dec 23
$101 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (2,155 reviews)
Good staff

Reviewed on Dec 17, 2025

Garden Place Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Buffalo

Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY

2.5 out of 5
164b Slade Ave Buffalo NY
$122 nightly
The price is $139 total per night from Jan 8 to Jan 9
$139 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,293 reviews)
The breakfast was very good for a free hotel breakfast. And the staff was very pleasant.

Reviewed on Dec 14, 2025

Country Inn & Suites by Radisson, Buffalo South I-90, NY
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
$84 nightly
The price is $96 total per night from Jan 8 to Jan 9
$96 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,900 reviews)
Seamless and easy check-in and check-out. Except I had to get my card re-activated EVERYDAY because it stopped working EVERYDAY 😡 that was annoying. The jacuzzi room was spacious but the king bed was old and worn out. It sunk in when you laid on it. Breakfast was good. Staff was friendly

Reviewed on Dec 16, 2025

Sleep Inn & Suites Buffalo Airport
Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG

3 out of 5
1290 Sweethome Rd Buffalo NY
$127 nightly
The price is $144 total per night from Jan 1 to Jan 2
$144 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,002 reviews)
Staff was warm and welcoming. Room was clean. Continental breakfast was tasty. Ample parking and amenities close by. Would definitely return.

Reviewed on Dec 13, 2025

Staybridge Suites Buffalo-Amherst by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SNA to BUF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
SNA Address & GPS
Address:
18601 Airport Way
Santa Ana CA, 92707
United States
IATA Code:
SNA
Longitude:
-117.860538
Latitude:
33.680201
Time Zone:
America/Los_Angeles
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from SNA to Buffalo Niagara Intl. Airport (BUF)?
Unfortunately, you won't find any direct flights on this route. But Southwest Airlines, United Airlines and Delta Air Lines will take you from John Wayne Airport (SNA) to Buffalo Niagara Intl. Airport (BUF) with only one stopover.
What is the shortest flight from SNA to Buffalo Niagara Intl. Airport (BUF)?
From Santa Ana, the exciting sights and sounds of Buffalo are around 5 hours and 46 minutes away. Book your favorite seat, or perhaps even upgrade to one with a little more legroom, and jet to your destination in pure comfort.
How many hours flight from John Wayne Airport to Buffalo Niagara International Airport?
Typically, it takes 5 hours and 50 minutes to get from John Wayne Airport to Buffalo Niagara International Airport. You'll be in your seat for a good amount of time, so bring plenty of entertainment, like a newspaper or your travel journal.
What airlines have the most flights from John Wayne Airport to BUF?
Pick up a souvenir, grab a quick meal, chat with a stranger ... Airport stopovers don't have to be something to dread! If you're planning to travel from Santa Ana to Buffalo, you can't fly direct. Get ready to make at least one stop somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.