Cheap flights from MSP to TYS (Minneapolis - St. Paul Intl. to McGhee Tyson)

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Cheap Flights from MSP to TYS starting at $143 One Way, $228 Round Trip

Prices starting at $228 for return flights and $143 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, May 25 - Thu, Jun 5
MSP
Minneapolis
TYS
Knoxville
$228 Roundtrip, found 2 days ago
$228
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, May 25 from Minneapolis to Knoxville, returning Thu, Jun 5, priced at $228 found 2 days ago
Thu, May 29 - Thu, Jun 5
MSP
Minneapolis
TYS
Knoxville
$248 Roundtrip, found 2 days ago
$248
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, May 29 from Minneapolis to Knoxville, returning Thu, Jun 5, priced at $248 found 2 days ago
Thu, May 22 - Sun, May 25
MSP
Minneapolis
TYS
Knoxville
$273 Roundtrip, found 23 hours ago
$273
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Thu, May 22 from Minneapolis to Knoxville, returning Sun, May 25, priced at $273 found 23 hours ago
Thu, May 22 - Thu, May 29
MSP
Minneapolis
TYS
Knoxville
$285 Roundtrip, found 3 days ago
$285
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, May 22 from Minneapolis to Knoxville, returning Thu, May 29, priced at $285 found 3 days ago
Thu, Aug 14 - Sun, Aug 17
MSP
Minneapolis
TYS
Knoxville
$292 Roundtrip, found 1 day ago
$292
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Aug 14 from Minneapolis to Knoxville, returning Sun, Aug 17, priced at $292 found 1 day ago

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from May 4 to May 5
$109
includes taxes & fees
$92 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,410 reviews)
"The main thing was getting onto highway to go to airport."

Reviewed on Apr 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport
Hilton Knoxville Airport
3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $181 per night from May 23 to May 24
$181
includes taxes & fees
$158 per night
May 23 - May 24
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,000 reviews)
"Quiet area, comfortable beds, clean rooms, easy check in, friendly staff."

Reviewed on Apr 27, 2025

Hilton Knoxville Airport
Tru by Hilton Alcoa Knoxville Airport
Tru by Hilton Alcoa Knoxville Airport
2.5 out of 5
125 FURROW WAY, Alcoa, TN
The price is $124 per night from May 26 to May 27
$124
includes taxes & fees
$105 per night
May 26 - May 27
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (540 reviews)
"First time staying at a Tru! Enjoyed my stay!"

Reviewed on Apr 26, 2025

Tru by Hilton Alcoa Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from May 4 to May 5
$109
includes taxes & fees
$92 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,410 reviews)
"The main thing was getting onto highway to go to airport."

Reviewed on Apr 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport
Hilton Knoxville Airport
3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $181 per night from May 23 to May 24
$181
includes taxes & fees
$158 per night
May 23 - May 24
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,000 reviews)
"Quiet area, comfortable beds, clean rooms, easy check in, friendly staff."

Reviewed on Apr 27, 2025

Hilton Knoxville Airport
Quality Inn Alcoa Knoxville
Quality Inn Alcoa Knoxville
2.5 out of 5
206 Corporate Pl, Alcoa, TN
The price is $98 per night from May 25 to May 26
$98
includes taxes & fees
$82 per night
May 25 - May 26
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,001 reviews)
"Convenience and nice staff"

Reviewed on Apr 20, 2025

Quality Inn Alcoa Knoxville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from May 4 to May 5
$109
includes taxes & fees
$92 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,410 reviews)
"The main thing was getting onto highway to go to airport."

Reviewed on Apr 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn
USA Inn
3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $70 per night from May 4 to May 5
$70
includes taxes & fees
$59 per night
May 4 - May 5
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (698 reviews)
"Ac was great, they have a minor roach and prostitution issue, couldn’t sleep without hearing them “working” or waiting outside for people every night."

Reviewed on Oct 6, 2024

USA Inn
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 4 to May 5
$96
includes taxes & fees
$81 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,003 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn
USA Inn
3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $70 per night from May 4 to May 5
$70
includes taxes & fees
$59 per night
May 4 - May 5
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (698 reviews)
"Ac was great, they have a minor roach and prostitution issue, couldn’t sleep without hearing them “working” or waiting outside for people every night."

Reviewed on Oct 6, 2024

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG
Candlewood Suites Knoxville Airport-Alcoa by IHG
2.5 out of 5
176 Cusick Road, Alcoa, TN
The price is $148 per night from May 25 to May 26
$148
includes taxes & fees
$125 per night
May 25 - May 26
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Meigs Falls and Palace Theater ...
8.2/10 Very Good! (539 reviews)
"Solid spot to stay near the airport"

Reviewed on Apr 25, 2025

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 4 to May 5
$96
includes taxes & fees
$81 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,003 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport
Comfort Suites Knoxville Airport
2.5 out of 5
140 Cusick Rd, Alcoa, TN
The price is $105 per night from Jun 1 to Jun 2
$105
includes taxes & fees
$88 per night
Jun 1 - Jun 2
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (667 reviews)
"Staff were all awesome! They were friendly and helpful. The pool and hot tub were not maintained— algae were growing in both."

Reviewed on Apr 27, 2025

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 4 to May 5
$96
includes taxes & fees
$81 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,003 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $109 per night from May 4 to May 5
$109
includes taxes & fees
$92 per night
May 4 - May 5
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,410 reviews)
"The main thing was getting onto highway to go to airport."

Reviewed on Apr 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MSP to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MSP Address & GPS
Address:
6040 28th Avenue South
Minneapolis MN, 55450
United States
IATA Code:
MSP
Longitude:
-93.210922
Latitude:
44.883016
Time Zone:
America/Chicago
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Am I able to catch a flight from Minneapolis, MN Airport (MSP-Minneapolis - St. Paul Intl.) to Knoxville, TN Airport (TYS-McGhee Tyson) now?
Go right to the Covid-19 Travel Advisor for the most useful info on travel restrictions and quarantine when flying from Minneapolis, MN Airport (MSP-Minneapolis - St. Paul Intl.) to Knoxville, TN Airport (TYS-McGhee Tyson).
Are there non-stop flights from Minneapolis - St. Paul Intl. Airport (MSP) to TYS?
You won’t have to worry about the hassle of switching planes or missing your next flight on this route. Delta will fly you nonstop from MSP to McGhee Tyson Airport (TYS).
What is the shortest flight from MSP to Knoxville Airport?
Grab the opportunity to chill out on your flight from Uptown to Old City. The fastest flight time from Minneapolis - St. Paul Intl. Airport (MSP) to Knoxville Airport is 4 hours and 15 minutes, which gives you plenty of time to enjoy a wine or get engrossed in a book.
How many hours flight from Minneapolis, MN Airport (MSP-Minneapolis - St. Paul Intl.) to TYS?
On a normal day, the journey from MSP to TYS takes 4 hours and 20 minutes. If you’re looking to be as comfortable as you can, think about upgrading your seat using air miles or cash.
If I am not able to travel due to COVID-19, can I cancel my flight to Knoxville, TN Airport (TYS-McGhee Tyson)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Knoxville, TN Airport (TYS-McGhee Tyson) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Knoxville, TN Airport (TYS-McGhee Tyson) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Knoxville, TN Airport (TYS-McGhee Tyson) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Wold--Chamberlain Field to Knoxville Airport?
Ready to book your Uptown to Old City airfare? Make Delta your number one pick. With 145 flights per month to pick from on this route, they’ve got the ticket to your next grand adventure.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.