Cheap flight deals from Rochester (ROC) to Quad Cities (MLI)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Quad Cities economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bally's Quad Cities
3.5-star property

Bally's Quad Cities

8.6/10 Excellent! (822 reviews)

Nov 13 - Nov 15

2 night stay

Rochester (ROC) to Moline (MLI)

American Airlines • Roundtrip • Coach
Price was $559, price is now $549 per person
$549
per person
found 1 day ago
Very nice hotel. Staff were professional and friendly.

Reviewed on Oct 3, 2026

Don't see what you're looking for?
See all available trips from Rochester to Quad Cities
View all trips

More About Flying To Quad Cities from Rochester

Route Information for Flights from Rochester to Quad Cities

Origin Airport IATA Code
ROC
Destination Airport IATA Code
MLI
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Rochester to Quad Cities

Score low fares on flights from Rochester to Quad Cities with Orbitz. We make it easier than ever to find cheap Rochester to Quad Cities flights with our cutting-edge mobile tools and mobile website.

Book Discount Flights From Rochester to Quad Cities in Minutes

If you are looking for low cost Rochester to Quad Cities flights, just skip all of the other so-called bargain travel sites, because Orbitz offers guaranteed low fares. That means you don't have to constantly scan multiple sites and hover like a vulture at your computer, hoping to score better deals through last-minute sales.

Find Bargain Rochester to Quad Cities Flights With Our Convenient Tools

You benefit from more than just cheap flights from Rochester to Quad Cities. Orbitz is a convenient one-stop trip planner. Research weather, attractions, and transportation options for Quad Cities to help you plan your trip and decide what to pack and where to go.

Booking domestic or international air fare and accommodations with Orbitz is a snap. Use your iPad, iPhone or Android device to find discount flights from Rochester to Quad Cities even while on the move, and sign up for instant email and text alerts to stay up-to-date on any delays affecting your flight. Or access m.orbitz.com via your mobile device’s Web browser.

Earn Miles through Orbitz for Your Frequent Flyer Program

You don't have to give up frequent flyer points to take advantage of our low fares. Add your frequent flyer number when you book your Rochester to Quad Cities flights to receive credit for your trip.

Frequently asked questions

What is the shortest flight from Rochester to Quad Cities?
It can take as little as 2 hours and 50 minutes to get from ROC to MLI. Buckle up and enjoy the ride, because you'll be coming in to land before you know it.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.