$80 Cheap flight deals from St. Louis (STL) to Panama City (PNS)

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This Weekend's Flight Deals from St. Louis to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Apr 20 - Sat, May 11
STL
Lambert-St. Louis Intl.
PNS
Pensacola Intl.
$174 Roundtrip, found 4 days ago
$174
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Apr 20 from Lambert-St. Louis Intl. to Pensacola Intl., returning Sat, May 11, priced at $174 found 4 days ago
Sat, Apr 20 - Wed, May 1
STL
Lambert-St. Louis Intl.
ECP
Northwest Florida Beaches Intl.
$299 Roundtrip, found 5 hours ago
$299
Roundtrip
found 5 hours ago
Select Delta flight, departing Sat, Apr 20 from Lambert-St. Louis Intl. to Northwest Florida Beaches Intl., returning Wed, May 1, priced at $299 found 5 hours ago

Airfares from $80 One Way, $138 Round Trip from St. Louis to Panama City

Prices starting at $138 for return flights and $80 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 3 - Mon, May 13
STL
St. Louis
PNS
Pensacola
$138 Roundtrip, found 4 days ago
$138
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, May 3 from St. Louis to Pensacola, returning Mon, May 13, priced at $138 found 4 days ago
Sat, May 18 - Tue, Jun 4
STL
St. Louis
PNS
Pensacola
$139 Roundtrip, found 4 days ago
$139
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, May 18 from St. Louis to Pensacola, returning Tue, Jun 4, priced at $139 found 4 days ago
Thu, Apr 25 - Fri, May 3
STL
St. Louis
PNS
Pensacola
$144 Roundtrip, found 6 days ago
$144
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Apr 25 from St. Louis to Pensacola, returning Fri, May 3, priced at $144 found 6 days ago
Tue, May 14 - Fri, May 17
STL
St. Louis
PNS
Pensacola
$155 Roundtrip, found 1 hour ago
$155
Roundtrip
found 1 hour ago
Select Spirit Airlines flight, departing Tue, May 14 from St. Louis to Pensacola, returning Fri, May 17, priced at $155 found 1 hour ago
Sun, Apr 28 - Mon, May 13
STL
St. Louis
PNS
Pensacola
$158 Roundtrip, found 4 days ago
$158
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Apr 28 from St. Louis to Pensacola, returning Mon, May 13, priced at $158 found 4 days ago

Panama City economy flight packages

Seahaven Beach Hotel
2.0-star property

Seahaven Beach Hotel

5.4/10 (1,339 reviews)

May 23 - May 27

4 night stay

St. Louis (STL) to Panama City (ECP)

Delta • Non-stop roundtrip • Coach
per person
Property needs alot of work

Reviewed on Mar 6, 2024

The Island Resort at Fort Walton Beach
4.0-star property

The Island Resort at Fort Walton Beach

8.4/10 Very Good! (1,846 reviews)

Jun 4 - Jun 8

4 night stay

St. Louis (STL) to Pensacola (PNS)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
per person
I like the various pools/hot tube. Unfortunately couldn't use too many amenities since they overbooked the area- optometry social, wedding, military event...bar area for happy hour couldn't be used.

Reviewed on Feb 26, 2024

Super 8 by Wyndham Ft Walton Beach
2.0-star property

Super 8 by Wyndham Ft Walton Beach

7.6/10 Good! (1,001 reviews)

Jun 4 - Jun 8

4 night stay

St. Louis (STL) to Pensacola (PNS)

American Airlines • Non-stop roundtrip • Coach
per person
Room was clean but smelled bad.

Reviewed on Jul 27, 2023

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Prices and availability subject to change. Additional terms may apply.

More About Flying To Panama City from St. Louis

Route Information for Flights from St. Louis to Panama City

Origin Airport IATA Code
STL
Destination Airport IATA Code
PNS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Panama City

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Frequently asked questions

Are there non-stop flights from St. Louis to Panama City?
Dust off your trusty passport, because Southwest Airlines will fly you straight from St. Louis to Panama City. Book your plane ticket now and enjoy a trouble-free, nonstop flight.
What is the shortest flight from St. Louis to Panama City?
The trip from St. Louis to Panama City can be as quick as 2 hours and 20 minutes. With a short and sweet flight time like this, why not book an impromptu getaway?
What airlines fly from St. Louis to Panama City most frequently?
If you’re looking for the airline with the most flights from St. Louis to Panama City, Southwest Airlines is the top pick. This well-known airline operates 39 flights along this route per month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won’t keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.