$301 Cheap flight deals from St. Louis (STL) to Panama City (PTY)

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Airfares from $301 One Way, $667 Round Trip from St. Louis to Panama City

Prices starting at $667 for return flights and $301 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, May 18 - Wed, May 19
STL
St. Louis
PTY
Panama City
$667 Roundtrip, found 4 days ago
$667
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 18 from St. Louis to Panama City, returning Wed, May 19, priced at $667 found 4 days ago
Tue, May 18 - Wed, May 19
STL
St. Louis
PTY
Panama City
$667 Roundtrip, found 4 days ago
$667
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, May 18 from St. Louis to Panama City, returning Wed, May 19, priced at $667 found 4 days ago
Tue, May 18 - Wed, May 19
STL
St. Louis
PTY
Panama City
$677 Roundtrip, found 4 days ago
$677
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, May 18 from St. Louis to Panama City, returning Wed, May 19, priced at $677 found 4 days ago
Tue, May 18 - Wed, May 19
STL
St. Louis
PTY
Panama City
$678 Roundtrip, found 4 days ago
$678
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, May 18 from St. Louis to Panama City, returning Wed, May 19, priced at $678 found 4 days ago
Mon, Dec 7 - Tue, Dec 22
STL
St. Louis
PTY
Panama City
$696 Roundtrip, found 22 hours ago
$696
Roundtrip
found 22 hours ago
Select Delta flight, departing Mon, Dec 7 from St. Louis to Panama City, returning Tue, Dec 22, priced at $696 found 22 hours ago

More About Flying To Panama City from St. Louis

Route Information for Flights from St. Louis to Panama City

Origin Airport IATA Code
STL
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Panama City

Great Deals on Flights From St. Louis to Panama City

Spend more of your time and money at Panama City instead of sitting at your computer, searching for discount St. Louis to Panama City flights. This is why Orbitz makes it easy for you to check out destinations, plan your trip, and book your air fare, hotel, car rental, and more in just one place. Our low price guarantee means that you get great deals on flights from St. Louis to Panama City.

Flights That Fit Your Budget

Traveling on a budget? Not to worry if you are using Orbitz. We monitor thousands of fares to make sure we show you the best air ticket prices available for your travel dates. Besides amazing prices on St. Louis to Panama City flights, we offer you great deals on hotels, vacation packages, and last-minute getaways for the perfect trip.

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Search for Flights from St. Louis to Panama City on the Go

Orbitz offers free mobile apps for iPad, iPhone, and Android-based devices, so even the busiest trip-planner can research and book flights from St. Louis to Panama City. Find cheap St. Louis to Panama City flights, research local festivities and attractions, and book reservations while sitting in the salon. Orbitz will also update you on flight delays with free alerts sent to your mobile phone or email address, so you’re never left in the dark.

Frequently asked questions

What is the shortest flight from St. Louis to Panama City?
Getting from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Panama City (PTY-Tocumen Intl.) will take you at least 5 hours and 30 minutes. Enjoy a wine and watch a show or two — here's your chance to sit back and chill out.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.