$220 Cheap flight deals from St. Louis (STL) to Panama City (PTY)
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Airfares from $220 One Way, $522 Round Trip from St. Louis to Panama City
Prices starting at $522 for return flights and $220 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Panama City economy flight packages
Hotel Riu Plaza Panama
May 21 - May 26
St. Louis (STL) to Panama City (PTY)
Reviewed on Mar 26, 2026
Megapolis Hotel Panamá
May 21 - May 26
St. Louis (STL) to Panama City (PTY)
Reviewed on Nov 16, 2025
More About Flying To Panama City from St. Louis
Route Information for Flights from St. Louis to Panama City
Origin Airport IATA Code | STL |
|---|---|
Destination Airport IATA Code | PTY |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
St. Louis to Panama City
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Orbitz shoppers can access affordable vacation packages and have the option of booking their departure and arrival flights through different airlines, making travel less costly and more convenient. The best prices on flights from St. Louis to Panama Cityare always found on Orbitz.
Frequently asked questions
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Flights to Panama City
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- Bethania Hotels
- Punta Pacifica Hotels
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- Hotels with Shopping in Causeway Islands
- Causeway Islands Hotels
- Hotels with Bar in Punta Paitilla
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.