$119 Cheap flight deals from Columbus (CMH) to Knoxville (DSM)
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Airfares from $119 One Way, $237 Round Trip from Columbus to Knoxville
Prices starting at $237 for return flights and $119 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Knoxville economy flight packages
Holiday Inn Downtown - Mercy Area by IHG
Sep 4 - Sep 7
Columbus (CMH) to Des Moines (DSM)
Reviewed on Aug 22, 2023
Hyatt Place Des Moines/Downtown
Sep 4 - Sep 7
Columbus (CMH) to Des Moines (DSM)
Reviewed on Jul 23, 2025
More About Flying To Knoxville from Columbus
Route Information for Flights from Columbus to Knoxville
Origin Airport IATA Code | CMH |
|---|---|
Destination Airport IATA Code | DSM |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Columbus to Knoxville
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Discount Travel Planning Made Simple
You will have no problems finding budget flights from Columbus to Knoxville on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.