$181 Cheap flight deals from Chicago (CHI) to Santee (CAE)
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Airfares from $181 One Way, $269 Round Trip from Chicago to Santee
Prices starting at $269 for return flights and $181 for one-way flights to Santee were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santee economy flight packages
Executive Inn Ridgeway I-77
Jul 2 - Jul 6
Chicago (CHI) to Columbia (CAE)
Reviewed on Jan 28, 2026
Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
Jul 2 - Jul 6
Chicago (CHI) to Columbia (CAE)
Reviewed on Nov 23, 2025
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Jul 2 - Jul 6
Chicago (CHI) to Columbia (CAE)
Reviewed on Feb 28, 2026
More About Flying To Santee from Chicago
Route Information for Flights from Chicago to Santee
Origin Airport IATA Code | CHI |
|---|---|
Destination Airport IATA Code | CAE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Chicago to Santee
Orbitz is your one-stop source for great online deals on {origin.name} to Santee flights. With our cutting-edge mobile tools and low fares, you are never far from finding fantastic savings on flights from Chicago to Santee.
Unbeatable Deals for Flights From Chicago to Santee
If you are looking for the cheapest {origin.name} to Santee flights, you can save your money and your sanity by booking your air fare through Orbitz. Our low price guarantee for international and domestic flights leaves more money in your wallet to spend on activities, restaurants, attractions, and other adventures in your destination.
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Don't Miss Out on Frequent Flyer Points
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Easy Flight Cancellation
In most cases, you can cancel flights from Chicago to Santee online with the same ease as you booked them.
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Santee Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.