$148 Cheap flight deals from Chicago (CHI) to Santee (CAE)

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This Weekend's Flight Deals from Chicago to Santee

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Nov 7 - Mon, Nov 10
ORD
O'Hare Intl.
CAE
Columbia Metropolitan
$324 Roundtrip, found 3 hours ago
$324
Roundtrip
found 3 hours ago
Select United flight, departing Fri, Nov 7 from O'Hare Intl. to Columbia Metropolitan, returning Mon, Nov 10, priced at $324 found 3 hours ago

Airfares from $148 One Way, $213 Round Trip from Chicago to Santee

Prices starting at $213 for return flights and $148 for one-way flights to Santee were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Dec 5 - Mon, Dec 8
ORD
Chicago
CAE
Columbia
$213 Roundtrip, found 3 hours ago
$213
Roundtrip
found 3 hours ago
Select United flight, departing Fri, Dec 5 from Chicago to Columbia, returning Mon, Dec 8, priced at $213 found 3 hours ago
Sat, Nov 22 - Thu, Nov 27
ORD
Chicago
CAE
Columbia
$213 Roundtrip, found 3 days ago
$213
Roundtrip
found 3 days ago
Select United flight, departing Sat, Nov 22 from Chicago to Columbia, returning Thu, Nov 27, priced at $213 found 3 days ago
Fri, May 15 - Sat, May 16
ORD
Chicago
CAE
Columbia
$219 Roundtrip, found 2 days ago
$219
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 15 from Chicago to Columbia, returning Sat, May 16, priced at $219 found 2 days ago
Fri, Dec 5 - Mon, Dec 8
ORD
Chicago
CAE
Columbia
$222 Roundtrip, found 3 hours ago
$222
Roundtrip
found 3 hours ago
Select United flight, departing Fri, Dec 5 from Chicago to Columbia, returning Mon, Dec 8, priced at $222 found 3 hours ago
Fri, May 15 - Sat, May 16
ORD
Chicago
CAE
Columbia
$223 Roundtrip, found 2 days ago
$223
Roundtrip
found 2 days ago
Select United flight, departing Fri, May 15 from Chicago to Columbia, returning Sat, May 16, priced at $223 found 2 days ago

Santee economy flight packages

Price found within the past 48 hours. Click for updated prices.
Sleep Inn Columbia
2.5-star property

Sleep Inn Columbia

8.2/10 Very Good! (1,013 reviews)

Dec 1 - Dec 4

3 night stay

Chicago (ORD) to Columbia (CAE)

Delta • Non-stop roundtrip • Coach
Price was $555, price is now $493 per person
$493
per person
found 12 hours ago
This property is definitely showing its age. The rooms feel dark and old, but they are definitely taken care of. The area itself is pretty rundown and for the price I was paying, I felt like it should have been a little more updated. One of the main reasons I chose the hotel was because of the continental breakfast and it really should be listed more as a grab and go option as the only thing that was Fresh was the waffle. Everything else is prepackaged items, which was disappointing.

Reviewed on Oct 14, 2025

Hilton Columbia Center
3.5-star property

Hilton Columbia Center

8.8/10 Excellent! (1,006 reviews)

Dec 1 - Dec 4

3 night stay

Chicago (ORD) to Columbia (CAE)

Delta • Non-stop roundtrip • Coach
Price was $1,066, price is now $901 per person
$901
per person
found 12 hours ago
Nice hotel. Would stay again.

Reviewed on Oct 21, 2025

Graduate by Hilton Columbia SC
4.0-star property

Graduate by Hilton Columbia SC

9.4/10 Exceptional! (1,019 reviews)

Dec 1 - Dec 4

3 night stay

Chicago (ORD) to Columbia (CAE)

Delta • Non-stop roundtrip • Coach
Price was $731, price is now $634 per person
$634
per person
found 12 hours ago
The Graduate Columbia is quaint, our GPS took us to the front of the building but the checkin desk is in the back so we thought we were walking into someone’s house! Obviously the entrance says Graduate so we knew we were in the right place. So the ground floor area is cute and cozy. The themed gamecock areas/rooms are fun and the convenience to USC is great, easy walk across the street. However, the rooms are pretty small and tight, the bathrooms even more so and the shower door is rusting, also the room/bathroom was not very clean. I had turned down housekeeping upon checkin, two nights, thought we would be in and out so much it would be easier and wouldn’t really need it. I wonder if the infrequent cleaning these days and then a rushed cleaning on room turnover is contributing to a less than thorough clean? Also the coffee in the room is instant? The latte from the bar downstairs was undrinkable, I threw it away. There is a cute coffee shop nearby on Gervais in an old funeral home that we got on our way out of town, highly recommend-knowledge coffee, also good breakfast sandwich. Overall it served its purpose for our college tour but if we came back I would look for somewhere else to stay.

Reviewed on Jul 29, 2025

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More About Flying To Santee from Chicago

Route Information for Flights from Chicago to Santee

Origin Airport IATA Code
CHI
Destination Airport IATA Code
CAE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Chicago to Santee

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.