Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Prices starting at $335 for return flights and $170 for one-way flights to Tri-Cities were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Origin Airport IATA Code
Destination Airport IATA Code
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival
The perfect trip begins with Orbitz. From booking your flights from Chicago to Tri-Cities to finding the best hotels, Orbitz has got it covered.
With an easy to use system, Orbitz takes the stress and expense out of travel. Not only does Orbitz match your Chicago to Tri-Cities flights to your ideal hotel, the Display Matrix shows your deals and discounts, including free nights and other savings.
Need to know what is going on at the airport before you get there? With Orbitz’s free alerts service, you can quickly find out about any booking changes, or flight from Chicago to Tri-Cities disruptions, saving you hours of wasted time. And if you are being picked up at the airport after your Chicago to Tri-Cities flights, have alerts sent straight to your contact’s mobile phone or email.
Find the best price on flights from Chicago to Tri-Cities with Orbitz’s mobile apps for iPhone and Android. Use m.orbitz.com on your mobile browser to check your gate, baggage allowance and delays, or find exclusive deals on hotels only available to mobile users.
Not only does booking with us ensure guaranteed low prices, but Orbitz does the hard work, leaving you to relax. Just tell us what you want, from Chicago to Tri-Cities flights, to great deals on hotels and car rental, and activities and tours, and we will do all the rest.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.