Cheap flights from ROA to EYW (Roanoke Regional to Key West Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from ROA to EYW starting at $144 One Way, $249 Round Trip

Prices starting at $249 for return flights and $144 for one-way flights to Key West Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Jan 6 - Tue, Jan 13
ROA
Roanoke
EYW
Key West
$249 Roundtrip, found 10 hours ago
$249
Roundtrip
found 10 hours ago
Select Delta flight, departing Tue, Jan 6 from Roanoke to Key West, returning Tue, Jan 13, priced at $249 found 10 hours ago
Tue, Jan 6 - Tue, Jan 13
ROA
Roanoke
EYW
Key West
$266 Roundtrip, found 10 hours ago
$266
Roundtrip
found 10 hours ago
Select Delta flight, departing Tue, Jan 6 from Roanoke to Key West, returning Tue, Jan 13, priced at $266 found 10 hours ago
Tue, Jan 6 - Tue, Jan 13
ROA
Roanoke
EYW
Key West
$287 Roundtrip, found 10 hours ago
$287
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Jan 6 from Roanoke to Key West, returning Tue, Jan 13, priced at $287 found 10 hours ago
Tue, Jan 6 - Tue, Jan 13
ROA
Roanoke
EYW
Key West
$289 Roundtrip, found 10 hours ago
$289
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Tue, Jan 6 from Roanoke to Key West, returning Tue, Jan 13, priced at $289 found 10 hours ago
Wed, Jan 7 - Tue, Jan 13
ROA
Roanoke
EYW
Key West
$294 Roundtrip, found 10 hours ago
$294
Roundtrip
found 10 hours ago
Select Delta flight, departing Wed, Jan 7 from Roanoke to Key West, returning Tue, Jan 13, priced at $294 found 10 hours ago

Hotel Ideas near Key West Intl.

Airport Hotels near Key West Intl.

Hyatt Vacation Club at Windward Pointe, Key West
Hyatt Vacation Club at Windward Pointe, Key West
3.5 out of 5
3675 South Roosevelt Boulevard, Key West, FL
$307 nightly
The price is $345 total per night from Aug 12 to Aug 13
$345 total
Aug 12 - Aug 13
Total includes taxes and fees
Stay at this 3.5-star eco-certified hotel in Key West. Enjoy free WiFi, free parking, and a snack bar/deli. Our guests praise the pool and the helpful staff ...
9.4/10 Exceptional! (1,007 reviews)
"Great hotel! Lot of amenities!"

Reviewed on Jul 10, 2025

Hyatt Vacation Club at Windward Pointe, Key West
Hampton Inn Key West FL
Hampton Inn Key West FL
2.5 out of 5
3755 S Roosevelt Blvd, Key West, FL
$189 nightly
The price is $213 total per night from Jul 13 to Jul 14
$213 total
Jul 13 - Jul 14
Total includes taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (1,181 reviews)
"Great property to stay at! Clean and good service."

Reviewed on Jul 9, 2025

Hampton Inn Key West FL
DoubleTree Resort by Hilton Grand Key - Key West
DoubleTree Resort by Hilton Grand Key - Key West
4 out of 5
3990 S Roosevelt Blvd, Key West, FL
$159 nightly
The price is $179 total per night from Aug 10 to Aug 11
$179 total
Aug 10 - Aug 11
Total includes taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
7.8/10 Good! (1,005 reviews)
"Pool was great"

Reviewed on Jul 10, 2025

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Key West

Beachside Resort & Residences
Beachside Resort & Residences
3.5 out of 5
3841 N Roosevelt Blvd, Key West, FL
$202 nightly
The price is $227 total per night from Jul 20 to Jul 21
$227 total
Jul 20 - Jul 21
Total includes taxes and fees
Stay at this 3.5-star beach hotel in Key West. Enjoy free WiFi, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,311 reviews)
"Few details. Leaky faucet, outer doors did not close all the way. Carded gates to stair wells did not work. Just a few more sun beds and umbrellas would be beneficial. But suite was well appointed, comfortable with everything needed. Had a nice relaxing time."

Reviewed on Jul 10, 2025

Beachside Resort & Residences
Southernmost Beach Resort and Guesthouses
Southernmost Beach Resort and Guesthouses
4 out of 5
1319 Duval Street, Key West, FL
$259 nightly
The price is $291 total per night from Aug 4 to Aug 5
$291 total
Aug 4 - Aug 5
Total includes taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,615 reviews)
"Second time at the resort. Hotel itself is a bit pricey but spacious and great location including dedicated beach. Rooms clean as friendly staff. Restaurants reasonably priced for the area. Considering the price, beach wasn’t cleaned of seaweed after the drought season leaving an awful smell across ..."

Reviewed on Jul 10, 2025

Southernmost Beach Resort and Guesthouses
Blue Flamingo Resort Key West
Blue Flamingo Resort Key West
4 out of 5
3820 North Roosevelt Boulevard, Key West, FL
$172 nightly
The price is $193 total per night from Aug 11 to Aug 12
$193 total
Aug 11 - Aug 12
Total includes taxes and fees
Stay at this 4-star eco-certified hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in ...
7.6/10 Good! (1,452 reviews)
"So many things to do, I traveled with my family and my dog and it was delightful."

Reviewed on Jul 10, 2025

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Key West Hotels With Airport Transportation

DoubleTree Resort by Hilton Grand Key - Key West
DoubleTree Resort by Hilton Grand Key - Key West
4 out of 5
3990 S Roosevelt Blvd, Key West, FL
$159 nightly
The price is $179 total per night from Aug 10 to Aug 11
$179 total
Aug 10 - Aug 11
Total includes taxes and fees
Stay at this 4-star business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
7.8/10 Good! (1,005 reviews)
"Pool was great"

Reviewed on Jul 10, 2025

DoubleTree Resort by Hilton Grand Key - Key West
Hampton Inn Key West FL
Hampton Inn Key West FL
2.5 out of 5
3755 S Roosevelt Blvd, Key West, FL
$189 nightly
The price is $213 total per night from Jul 13 to Jul 14
$213 total
Jul 13 - Jul 14
Total includes taxes and fees
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (1,181 reviews)
"Great property to stay at! Clean and good service."

Reviewed on Jul 9, 2025

Hampton Inn Key West FL
Eden House
Eden House
3.5 out of 5
1015 Fleming St, Key West, FL
$196 nightly
The price is $220 total per night from Jul 14 to Jul 15
$220 total
Jul 14 - Jul 15
Total includes taxes and fees
Stay at this 3.5-star hotel in Key West. Enjoy free WiFi, in-room massages, and a 24-hour front desk. Our guests praise the pool and the helpful staff in our ...
9/10 Wonderful! (1,002 reviews)
"It's a great place to stay away from the bustle and noise of the bars and tourist activities, but it's still conveniently a quick walk away."

Reviewed on Jul 9, 2025

Eden House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Key West Hotels

Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
$150 nightly
The price is $169 total per night from Jul 14 to Jul 15
$169 total
Jul 14 - Jul 15
Total includes taxes and fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,116 reviews)
"property was good for the cost"

Reviewed on Jul 8, 2025

Southwinds Motel
Seashell Motel & Key West Hostel
Seashell Motel & Key West Hostel
1.5 out of 5
718 South Street, Key West, FL
$130 nightly
The price is $146 total per night from Aug 10 to Aug 11
$146 total
Aug 10 - Aug 11
Total includes taxes and fees
Stay at this hostel in Key West. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.6/10 Good! (1,002 reviews)
Hidden gem
"Great little place. Really clean. Only two things stood out really. There is construction on the property, so parts of it were a mess. They upgraded us to a suite when we got there, which was great. But the front "living area" air conditioner struggled a bit. The one in the sleeping area was as cold ..."

Reviewed on Jul 9, 2025

Seashell Motel & Key West Hostel
Duval House
Duval House
3 out of 5
815 Duval St, Key West, FL
$131 nightly
The price is $144 total per night from Jul 15 to Jul 16
$144 total
Jul 15 - Jul 16
Total includes taxes and fees
Stay at this 3-star B&B in Key West. Enjoy parking (surcharge), daily housekeeping, and a garden. Our guests praise the breakfast and the pool in our reviews. ...
9.4/10 Exceptional! (1,009 reviews)
"We had an amazing time at duval house. We will be back. You are in crime real estate. The breakfast was amazing. The staff was super friendly. And we rented the bikes for every day, which was awesome. I do recommend renting bikes while you’re on the vacation. It’s $30 a day to park your car."

Reviewed on Jul 9, 2025

Duval House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Key West

Southernmost Beach Resort and Guesthouses
Southernmost Beach Resort and Guesthouses
4 out of 5
1319 Duval Street, Key West, FL
$259 nightly
The price is $291 total per night from Aug 4 to Aug 5
$291 total
Aug 4 - Aug 5
Total includes taxes and fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,615 reviews)
"Second time at the resort. Hotel itself is a bit pricey but spacious and great location including dedicated beach. Rooms clean as friendly staff. Restaurants reasonably priced for the area. Considering the price, beach wasn’t cleaned of seaweed after the drought season leaving an awful smell across ..."

Reviewed on Jul 10, 2025

Southernmost Beach Resort and Guesthouses
Margaritaville Beach House Key West
Margaritaville Beach House Key West
4 out of 5
2001 South Roosevelt Blvd, Key West, FL
Stay at this 4-star beach hotel in Key West. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Popular attractions Duval Street and Smathers Beach ...
8.2/10 Very Good! (1,000 reviews)

Families like: Outdoor pool, babysitting, close to beach, bicycle rentals

Travelers say...
"Everything was was great"

Reviewed on May 9, 2025

Get rates
Margaritaville Beach House Key West
Blue Flamingo Resort Key West
Blue Flamingo Resort Key West
4 out of 5
3820 North Roosevelt Boulevard, Key West, FL
$172 nightly
The price is $193 total per night from Aug 11 to Aug 12
$193 total
Aug 11 - Aug 12
Total includes taxes and fees
Stay at this 4-star eco-certified hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in ...
7.6/10 Good! (1,452 reviews)

Families like: Outdoor pools, miniature golf, game room, bicycle rentals

Travelers say...
"So many things to do, I traveled with my family and my dog and it was delightful."

Reviewed on Jul 10, 2025

Blue Flamingo Resort Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ROA to EYW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ROA Address & GPS
Address:
5202 Aviation Drive, N.W.
Roanoke VA, 24012-1148
United States
IATA Code:
ROA
Longitude:
-79.970384
Latitude:
37.320509
Time Zone:
America/New_York
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from ROA to EYW?
With no direct flights operating from Roanoke--Blacksburg Regional Airport to Key West Intl. Airport, your best bet is to choose a carrier that offers just one simple stopover. Collect a few more air miles with American Airlines, Delta Air Lines or United Airlines.
What is the shortest flight from ROA to EYW?
Treat yourself to an in-flight wine and get comfy in your seat with a riveting movie or book. With the flight from Roanoke to Key West taking 4 hours and 40 minutes, you'll have plenty of time to sit back and enjoy the experience.
How many hours flight from Roanoke Regional Airport (ROA) to Key West Intl. Airport (EYW)?
The journey from Roanoke Regional Airport (ROA) to Key West Intl. Airport takes an average of 4 hours and 43 minutes. A few movies, some podcasts and a nice snooze will make the time fly.
What airlines have the most flights from ROA to Key West Intl. Airport (EYW)?
Unfortunately, you won't find any direct flights from Roanoke to Key West. However, you will be able to book a flight with at least one stop. There's always a positive side --- use the time to stretch your tired legs or sit down for a nice coffee!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.