Cheap flights from MLI to SNA (Quad City Intl. to John Wayne)

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Cheap Flights from MLI to SNA starting at $381 One Way, $384 Round Trip

Prices starting at $384 for return flights and $381 for one-way flights to John Wayne were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Nov 6 - Thu, Nov 12
MLI
Moline
SNA
Orange County
$384 Roundtrip, found 17 hours ago
$384
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Fri, Nov 6 from Moline to Orange County, returning Thu, Nov 12, priced at $384 found 17 hours ago
Fri, Apr 23 - Mon, May 3
MLI
Moline
SNA
Orange County
$401 Roundtrip, found 2 days ago
$401
Roundtrip
found 2 days ago
Select United flight, departing Fri, Apr 23 from Moline to Orange County, returning Mon, May 3, priced at $401 found 2 days ago
Fri, Nov 6 - Thu, Nov 12
MLI
Moline
SNA
Orange County
$478 Roundtrip, found 17 hours ago
$478
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Fri, Nov 6 from Moline to Orange County, returning Thu, Nov 12, priced at $478 found 17 hours ago
Fri, Apr 23 - Mon, May 3
MLI
Moline
SNA
Orange County
$486 Roundtrip, found 2 days ago
$486
Roundtrip
found 2 days ago
Select United flight, departing Fri, Apr 23 from Moline to Orange County, returning Mon, May 3, priced at $486 found 2 days ago
Fri, Apr 23 - Mon, May 3
MLI
Moline
SNA
Orange County
$494 Roundtrip, found 2 days ago
$494
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Apr 23 from Moline to Orange County, returning Mon, May 3, priced at $494 found 2 days ago

Hotel Ideas near John Wayne

Airport Hotels near John Wayne

Hyatt Regency Newport Beach West

Hyatt Regency Newport Beach West

4 out of 5
4545 Macarthur Blvd Newport Beach CA
$203 nightly
The price is $224 total per night from Oct 11 to Oct 12
$224 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Newport Beach. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
9/10 Wonderful! (1,008 reviews)
"Door to pool fell off the hinges as a lady opened it. Hot tub worked the first day but the jets did not work the second day. Bar is hardly ever open. Got a rancid glass of red wine and told the bartender. He said they do t serve that kind much and that was all he said. Did not offer refund or another ..."

Reviewed on Oct 1, 2026

Hyatt Regency Newport Beach West
Renaissance Newport Beach Hotel

Renaissance Newport Beach Hotel

4 out of 5
4500 Macarthur Blvd Newport Beach CA
$207 nightly
The price is $228 total per night from Oct 30 to Oct 31
$228 total
Oct 30 - Oct 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Newport Beach. Enjoy a free airport shuttle, room service, and a 24-hour fitness center. Our guests praise the ...
9/10 Wonderful! (1,104 reviews)
"Great hotel and location"

Reviewed on Oct 2, 2026

Renaissance Newport Beach Hotel
Ayres Hotel Costa Mesa/Newport Beach

Ayres Hotel Costa Mesa/Newport Beach

4 out of 5
325 Bristol Street Costa Mesa CA
$152 nightly
The price is $169 total per night from Oct 13 to Oct 14
$169 total
Oct 13 - Oct 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Costa Mesa. Enjoy free WiFi, 2 outdoor pools, and a free airport shuttle. Our guests praise the breakfast and ...
Ayres Hotel Costa Mesa/Newport Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Orange County

MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
$93 nightly
The price is $105 total per night from Oct 25 to Oct 26
$105 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
MainStay Suites John Wayne Airport by Choice Hotels
Hilton Anaheim

Hilton Anaheim

4 out of 5
777 W Convention Way Anaheim CA
$194 nightly
The price is $227 total per night from Oct 31 to Nov 1
$227 total
Oct 31 - Nov 1
Total with taxes and fees
Book a stay at this family-friendly hotel in Anaheim. Enjoy 4 restaurants, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and ...
Hilton Anaheim
Anaheim Majestic Garden Hotel

Anaheim Majestic Garden Hotel

3.5 out of 5
900 S Disneyland Dr Anaheim CA
$169 nightly
The price is $198 total per night from Oct 19 to Oct 20
$198 total
Oct 19 - Oct 20
Total with taxes and fees
Book a stay at this family-friendly hotel in Anaheim. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (5,894 reviews)
"loved it it was clean magical and the shuttle to disney was great but the insane amount of money it was to park my car there was absurd"

Reviewed on Oct 2, 2026

Anaheim Majestic Garden Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Orange County Hotels With Airport Transportation

MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
$93 nightly
The price is $105 total per night from Oct 25 to Oct 26
$105 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
MainStay Suites John Wayne Airport by Choice Hotels
Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North

2.5 out of 5
2700 Hotel Terrace Dr. Santa Ana CA
$113 nightly
The price is $128 total per night from Oct 4 to Oct 5
$128 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Best Western Plus Orange County Airport North
Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton

4 out of 5
201 E MacArthur Blvd Santa Ana CA
$130 nightly
The price is $147 total per night from Oct 30 to Oct 31
$147 total
Oct 30 - Oct 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
9/10 Wonderful! (811 reviews)
"It was overall a nice place to stay at."

Reviewed on Oct 2, 2026

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Orange County Hotels

Motel 6 Santa Ana, CA

Motel 6 Santa Ana, CA

2 out of 5
1623 East 1st Street Santa Ana CA
$83 nightly
The price is $93 total per night from Oct 11 to Oct 12
$93 total
Oct 11 - Oct 12
Total with taxes and fees
Stay at this motel in Santa Ana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,006 reviews)
"This is the first time I stay at this motel and was so happy. I got there very tired and needed to take a nap before going on to other activities and the counter assistance I got was superb and the ladies name was Karina and I wanna say that she made me feel very comfortable and provided me with ..."

Reviewed on Oct 2, 2026

Motel 6 Santa Ana, CA
Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North

2.5 out of 5
2700 Hotel Terrace Dr. Santa Ana CA
$113 nightly
The price is $128 total per night from Oct 4 to Oct 5
$128 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Best Western Plus Orange County Airport North
La Quinta Inn & Suites by Wyndham Orange County Airport

La Quinta Inn & Suites by Wyndham Orange County Airport

3 out of 5
2721 Hotel Ter Santa Ana CA
$92 nightly
The price is $104 total per night from Oct 11 to Oct 12
$104 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (2,146 reviews)
"The rooms here are very spacious, there is plenty of parking, they offer a good breakfast and is conveniently located near major freeways. The carpet was stained since they accepted pets. The staff was helpful but they do not do daily room service."

Reviewed on Oct 2, 2026

La Quinta Inn & Suites by Wyndham Orange County Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Orange County

Embassy Suites by Hilton Santa Ana Orange County Airport

Embassy Suites by Hilton Santa Ana Orange County Airport

3.5 out of 5
1325 East Dyer Road Santa Ana CA
$118 nightly
The price is $134 total per night from Oct 11 to Oct 12
$134 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the breakfast and ...
Embassy Suites by Hilton Santa Ana Orange County Airport
MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
$93 nightly
The price is $105 total per night from Oct 25 to Oct 26
$105 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
MainStay Suites John Wayne Airport by Choice Hotels
Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North

2.5 out of 5
2700 Hotel Terrace Dr. Santa Ana CA
$113 nightly
The price is $128 total per night from Oct 4 to Oct 5
$128 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Best Western Plus Orange County Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MLI to SNA Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MLI Address & GPS
Address:
2200 69th Ave.
Moline IL, 61265
United States
IATA Code:
MLI
Longitude:
-90.506111
Latitude:
41.453897
Time Zone:
America/Chicago
SNA Address & GPS
Address:
18601 Airport Way
Santa Ana CA, 92707
United States
IATA Code:
SNA
Longitude:
-117.860538
Latitude:
33.680201
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from Quad City Intl. Airport (MLI) to John Wayne Airport (SNA)?
Traveling from Quad City Intl. Airport to John Wayne Airport means you'll need to swap planes. But hey — that's OK. American Airlines, United Airlines and Delta Air Lines offer flights with a single stopover.
What is the shortest flight from Quad City Intl. Airport (MLI) to John Wayne Airport?
From Moline, the thrilling sights and sounds of Santa Ana are 6 hours and 9 minutes away. Book your favorite seat, or maybe even upgrade to one with extra legroom, and get to your destination in pure comfort.
How many hours flight from Quad City Intl. Airport (MLI) to John Wayne Airport?
From Quad City Intl. Airport to John Wayne Airport, you'll be cruising the skies for approximately 6 hours and 15 minutes. Get comfy, order a glass of bubbly and put on your noise-canceling earphones. It's time to binge-watch some awesome TV shows.
What airlines have the most flights from Quad City Intl. Airport to SNA?
Unfortunately there are no airlines that fly direct between MLI and John Wayne Airport. Plan ahead and secure a multi-stop or one-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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