
$78 Cheap flight deals from St. Louis (STL) to Santa Ana (QLA)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from St. Louis to Santa Ana
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $78 One Way, $154 Round Trip from St. Louis to Santa Ana
Prices starting at $154 for return flights and $78 for one-way flights to Santa Ana were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santa Ana economy flight packages

Motel 6 Stanton, CA - Anaheim West
Oct 29 - Nov 4
St. Louis (STL) to Orange County (SNA)
Orange County (SNA) to St. Louis (STL)
Reviewed on Jul 22, 2025

Waldorf Astoria Monarch Beach Resort & Club
Oct 31 - Nov 3
St. Louis (STL) to Orange County (SNA)
Reviewed on Jun 28, 2024

Balboa Bay Resort
Nov 15 - Nov 19
St. Louis (STL) to Orange County (SNA)
Reviewed on Jun 4, 2024
More About Flying To Santa Ana from St. Louis
Route Information for Flights from St. Louis to Santa Ana
Origin Airport IATA Code | STL |
---|---|
Destination Airport IATA Code | QLA |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
St. Louis to Santa Ana
If it is not enough that we have guaranteed low prices for St. Louis to Santa Ana flights, Orbitz can also integrate your hotel and car rental needs into the package. This ensures your trip goes smoothly and you get the best possible bargain.
Save Big On Hotels With Our Summer Hotel Sale When Booking St. Louis to Santa Ana Flights
We will get you bargain air tickets for St. Louis to Santa Ana flights and can save you even more with our Summer Hotel sale. You can get a discount of up to 40% when you book a hotel along with your bargain flight from Orbitz.
If You Are Going To The Beach We Can Save You Even More
When you are arranging budget flights from St. Louis to Santa Ana, you can save even more by staying near a beach. Orbitz Beach Hotel Deals will allow you to get as much as half off the price of an already cheap hotel. Saving money has never been this fun.
Plan A Spontaneous Trip Using Our Top Hotel and Flight Destinations
Want to know where other people are staying after flights from St. Louis to Santa Ana? We not only recommend top destinations, but will tell you the most popular places to stay after {origin.name} to Santa Ana flights.
Use Orbitz.com For Up To The Minute Hot Deals
Budget deals on flights from St. Louis to Santa Ana are constantly changing. You can get up-to-the-minute updates on the hottest deals on discount tickets and hotels on our website.
- Flights to Santa Ana
- Flights from St. Louis
- St. Louis Airports
- Santa Ana Airports
- Airlines Operating
- Book on Expedia
Flights to Santa Ana
- Seattle to Santa Ana
- Denver to Santa Ana
- Phoenix to Santa Ana
- Dallas to Santa Ana
- Chicago to Santa Ana
- New York to Santa Ana
- Houston to Santa Ana
- San Luis Obispo to Santa Ana
- New Orleans to Santa Ana
- Montreal to Santa Ana
- Orlando to Santa Ana
- Los Angeles to Santa Ana
- Beijing to Santa Ana
- Buenos Aires to Santa Ana
- Detroit to Santa Ana
- Istanbul to Santa Ana
- Kansas City to Santa Ana
- London to Santa Ana
- San Francisco to Santa Ana
- Toronto to Santa Ana
Flights from St. Louis
- St. Louis to Orlando
- St. Louis to New York
- St. Louis to Houston
- St. Louis to Dallas
- St. Louis to Chicago
- St. Louis to Denver
- St. Louis to Atlanta
- St. Louis to Phoenix
- St. Louis to Los Angeles
- St. Louis to New Orleans
- St. Louis to Toronto
- St. Louis to Detroit
- St. Louis to Washington
- St. Louis to Kansas City
- St. Louis to London
- St. Louis to Cleveland
- St. Louis to San Francisco
- St. Louis to Rome
- St. Louis to Montreal
- St. Louis to Vancouver
St. Louis Airports
Santa Ana Airports
- Visit Disneyland® Resort
- Hotels near Disneyland® Resort
- Car rentals in Los Angeles
- Flights to Los Angeles
- Hotels in Orange County
- Flights to Orange County
- Car rentals at Orange County Airport (SNA)
- Car rentals in Tustin
- Flights to Tustin
- Hotels in Tustin
- Car rentals in Orange County
- Cheap Hotels in Tustin
- Flights to Anaheim
- Visit Bowers Museum
- Hotels in Anaheim
Top Trending
- Cheap Los Angeles to Cabo San Lucas flights
- Cheap New York to Orlando flights
- Cheap Toronto to Orlando flights
- Cheap Toronto to Miami flights
- Cheap Los Angeles to New York flights
- Cheap Chicago to Las Vegas flights
- Cheap New York to Los Angeles flights
- Cheap Atlanta to Las Vegas flights
- Cheap Orlando to Miami flights
- Cheap New York to Las Vegas flights
- Cheap Seattle to Las Vegas flights
- Cheap Boston to Orlando flights
- Cheap Chicago to Phoenix flights
- Cheap Vancouver to Las Vegas flights
- Cheap Portland to Las Vegas flights
- Cheap Toronto to Las Vegas flights
- Cheap Houston to Las Vegas flights
- Cheap Denver to Las Vegas flights
- Cheap New York to Miami flights
- Cheap Los Angeles to Las Vegas flights
- Cheap Minneapolis - St. Paul to Las Vegas flights
- Cheap Toronto to Los Angeles flights
- Cheap Chicago to New York flights
- Cheap New York to Atlanta flights
- Cheap Atlanta to New York flights
- Cheap Atlanta to Miami flights
- Cheap New York to London flights
- Cheap Toronto to New York flights
- Cheap Dallas to Las Vegas flights
- Cheap Detroit to Las Vegas flights
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.