$90 Cheap flight deals from St. Louis (STL) to Santa Ana (QLA)

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This Weekend's Flight Deals from St. Louis to Santa Ana

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 15 - Sat, Aug 16
STL
Lambert-St. Louis Intl.
ONT
Los Angeles - Ontario Intl.
$222 Roundtrip, found 23 hours ago
$222
Roundtrip
found 23 hours ago
Select Frontier Airlines flight, departing Fri, Aug 15 from Lambert-St. Louis Intl. to Los Angeles - Ontario Intl., returning Sat, Aug 16, priced at $222 found 23 hours ago
Sat, Aug 16 - Mon, Aug 25
STL
Lambert-St. Louis Intl.
LAX
Los Angeles Intl.
$320 Roundtrip, just found
$320
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, Aug 16 from Lambert-St. Louis Intl. to Los Angeles Intl., returning Mon, Aug 25, priced at $320 just found
Fri, Aug 15 - Sun, Aug 17
STL
Lambert-St. Louis Intl.
SNA
John Wayne
$428 Roundtrip, found 10 hours ago
$428
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Fri, Aug 15 from Lambert-St. Louis Intl. to John Wayne, returning Sun, Aug 17, priced at $428 found 10 hours ago
Sat, Aug 16 - Wed, Aug 20
STL
Lambert-St. Louis Intl.
LGB
Long Beach Municipal
$692 Roundtrip, found 3 days ago
$692
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Aug 16 from Lambert-St. Louis Intl. to Long Beach Municipal, returning Wed, Aug 20, priced at $692 found 3 days ago

Airfares from $90 One Way, $178 Round Trip from St. Louis to Santa Ana

Prices starting at $178 for return flights and $90 for one-way flights to Santa Ana were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Oct 22 - Sat, Oct 25
STL
St. Louis
SNA
Orange County
$178 Roundtrip, found 3 days ago
$178
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, Oct 22 from St. Louis to Orange County, returning Sat, Oct 25, priced at $178 found 3 days ago
Wed, Oct 22 - Sat, Oct 25
STL
St. Louis
SNA
Orange County
$179 Roundtrip, found 3 days ago
$179
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 22 from St. Louis to Orange County, returning Sat, Oct 25, priced at $179 found 3 days ago
Wed, Oct 22 - Sat, Oct 25
STL
St. Louis
SNA
Orange County
$182 Roundtrip, found 3 days ago
$182
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, Oct 22 from St. Louis to Orange County, returning Sat, Oct 25, priced at $182 found 3 days ago
Thu, Sep 4 - Tue, Sep 9
STL
St. Louis
LAX
Los Angeles
$193 Roundtrip, found 3 days ago
$193
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Sep 4 from St. Louis to Los Angeles, returning Tue, Sep 9, priced at $193 found 3 days ago
Sat, Nov 8 - Sat, Nov 15
STL
St. Louis
ONT
Ontario
$205 Roundtrip, found 1 day ago
$205
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Nov 8 from St. Louis to Ontario, returning Sat, Nov 15, priced at $205 found 1 day ago

Santa Ana economy flight packages

Price found within the past 48 hours. Click for updated prices.
Atrium Hotel at Orange County Airport
3.0-star property

Atrium Hotel at Orange County Airport

7.6/10 Good! (1,850 reviews)

Sep 19 - Sep 22

3 night stay

St. Louis (STL) to Orange County (SNA)

American Airlines • Non-stop roundtrip • Coach
per person
found 1 day ago
Pleasant and efficient staff

Reviewed on Aug 8, 2025

Balboa Bay Resort
4.5-star property

Balboa Bay Resort

9/10 Wonderful! (1,002 reviews)

Sep 19 - Sep 22

3 night stay

St. Louis (STL) to Orange County (SNA)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
We love the experience. We have been there many times and love the water. We hosted cocktail hours there for many years when we lived and worked locally. The only issue we had this visit was the food. We felt the food was marginal. The service was great as usual and overall had a good visit.

Reviewed on Jun 4, 2024

ALO Hotel by Ayres, Orange
3.5-star property

ALO Hotel by Ayres, Orange

9/10 Wonderful! (2,229 reviews)

Sep 19 - Sep 22

3 night stay

St. Louis (STL) to Orange County (SNA)

American Airlines • Non-stop roundtrip • Coach
per person
found 1 day ago
Nice breakfast, respectful staff, thank you.

Reviewed on Apr 4, 2025

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More About Flying To Santa Ana from St. Louis

Route Information for Flights from St. Louis to Santa Ana

Origin Airport IATA Code
STL
Destination Airport IATA Code
QLA
Distance
1588 mi
Direct Flight Airlines
American Airlines, Qatar Airways, JAL, Alaska Airlines, Qantas, Cathay Pacific, Southwest Airlines, Air Tahiti Nui, Malaysia Airlines
Earliest Flight Arrival
1:20PM UTC
Latest Flight Arrival
2:10AM UTC

St. Louis to Santa Ana

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Orbitz Flights Fit Around Your Lifestyle

Orbitz understands that you don’t necessarily want to fly at 5:00 a.m—and that sometimes you do. This is why we allow you to find the best St. Louis to Santa Ana flights at the times you want with ease.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.