Cheap flights from MDT to TYS (Harrisburg Intl. to McGhee Tyson)
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Cheap Flights from MDT to TYS starting at $149 One Way, $249 Round Trip
Prices starting at $249 for return flights and $149 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
MDT
Harrisburg
TYS
Knoxville
$249 Roundtrip, found 2 days ago
$249
Roundtrip
found 2 days ago
MDT
Harrisburg
TYS
Knoxville
$250 Roundtrip, found 5 days ago
$250
Roundtrip
found 5 days ago
MDT
Harrisburg
TYS
Knoxville
$254 Roundtrip, found 2 days ago
$254
Roundtrip
found 2 days ago
MDT
Harrisburg
TYS
Knoxville
$260 Roundtrip, found 4 days ago
$260
Roundtrip
found 4 days ago
MDT
Harrisburg
TYS
Knoxville
$273 Roundtrip, found 6 days ago
$273
Roundtrip
found 6 days ago
Hotel Ideas near McGhee Tyson
Airport Hotels near McGhee Tyson
Hilton Knoxville Airport
2001 Alcoa Hwy Alcoa TN
$116 nightly
The price is $134 total per night from Feb 7 to Feb 8
$134 total
Feb 7 - Feb 8
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,009 reviews)
Everything was great!
Reviewed on Jan 22, 2026
La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$75 nightly
The price is $89 total per night from Feb 15 to Feb 16
$89 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,729 reviews)
Todo muy muy limpio, el staff muy amable y eficiente, inluye desayuno
Reviewed on Jan 24, 2026
Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Feb 8 to Feb 9
$82 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,007 reviews)
Clean rooms and nice stsff
Reviewed on Jan 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Knoxville
Hilton Knoxville Airport
2001 Alcoa Hwy Alcoa TN
$116 nightly
The price is $134 total per night from Feb 7 to Feb 8
$134 total
Feb 7 - Feb 8
Total with taxes and fees
Book a stay at this family-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,009 reviews)
Everything was great!
Reviewed on Jan 22, 2026
La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$75 nightly
The price is $89 total per night from Feb 15 to Feb 16
$89 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,729 reviews)
Todo muy muy limpio, el staff muy amable y eficiente, inluye desayuno
Reviewed on Jan 24, 2026
Mainstay Suites Knoxville Airport
361 Fountain View Cir Alcoa TN
$76 nightly
The price is $90 total per night from Jan 30 to Jan 31
$90 total
Jan 30 - Jan 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (695 reviews)
Good
Reviewed on Jan 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Knoxville Hotels With Airport Transportation
La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$75 nightly
The price is $89 total per night from Feb 15 to Feb 16
$89 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,729 reviews)
Todo muy muy limpio, el staff muy amable y eficiente, inluye desayuno
Reviewed on Jan 24, 2026
USA Inn
Alcoa Hwy, 2962 Alcoa TN
$55 nightly
The price is $66 total per night from Jan 30 to Jan 31
$66 total
Jan 30 - Jan 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Many. Bugs. Full size mattresses on cots. We need a room we missed a flight. We needed some space to sleep, we got it. Minus the sleep.
Reviewed on Sep 16, 2025
Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Feb 8 to Feb 9
$82 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,007 reviews)
Clean rooms and nice stsff
Reviewed on Jan 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Knoxville Hotels
USA Inn
Alcoa Hwy, 2962 Alcoa TN
$55 nightly
The price is $66 total per night from Jan 30 to Jan 31
$66 total
Jan 30 - Jan 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (714 reviews)
Many. Bugs. Full size mattresses on cots. We need a room we missed a flight. We needed some space to sleep, we got it. Minus the sleep.
Reviewed on Sep 16, 2025
Candlewood Suites Knoxville Airport-Alcoa by IHG
176 Cusick Road Alcoa TN
$71 nightly
The price is $84 total per night from Feb 15 to Feb 16
$84 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, an outdoor pool, and a free airport shuttle. Popular attractions Meigs Falls and Palace ...
8.2/10 Very Good! (615 reviews)
Good atención.. clean.. amazing room
Reviewed on Jan 24, 2026
Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Feb 8 to Feb 9
$82 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,007 reviews)
Clean rooms and nice stsff
Reviewed on Jan 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Knoxville
Comfort Suites Knoxville Airport
140 Cusick Rd Alcoa TN
$72 nightly
The price is $86 total per night from Feb 5 to Feb 6
$86 total
Feb 5 - Feb 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (761 reviews)
Exellent
Reviewed on Jan 25, 2026
Best Western Knoxville Airport/Alcoa
162 Cusick Rd Alcoa TN
$69 nightly
The price is $82 total per night from Feb 8 to Feb 9
$82 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,007 reviews)
Clean rooms and nice stsff
Reviewed on Jan 26, 2026
La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road Alcoa TN
$75 nightly
The price is $89 total per night from Feb 15 to Feb 16
$89 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,729 reviews)
Todo muy muy limpio, el staff muy amable y eficiente, inluye desayuno
Reviewed on Jan 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
MDT to TYS Route Info
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MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
Other Flights from Harrisburg Intl. Airport (MDT)
Other Flights to McGhee Tyson Airport (TYS)
- Capital City Airport (HAR)
- Lancaster Airport (LNS)
- Penn Valley Airport (SEG)
- Reading Regional Airport (RDG)
- Hagerstown Regional Airport (HGR)
- Martin State Airport (MTN)
- Baltimore Washington Intl. Thurgood Marshall Airport (BWI)
- Williamsport Regional Airport (IPT)
- University Park Airport (SCE)
- Montgomery County Airpark Airport (GAI)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.