Cheap flights from LAX to FLO (Los Angeles Intl. to Florence Regional)

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Cheap Flights from LAX to FLO starting at One Way, $542 Round Trip

Prices starting at $542 for return flights and for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Dec 31 - Sat, Jan 3
LAX
Los Angeles
FLO
Florence
$542 Roundtrip, found 18 hours ago
$542
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Los Angeles to Florence, returning Sat, Jan 3, priced at $542 found 18 hours ago
Fri, Jan 2 - Mon, Jan 5
LAX
Los Angeles
FLO
Florence
$558 Roundtrip, found 18 hours ago
$558
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Mon, Jan 5, priced at $558 found 18 hours ago
Fri, Jan 2 - Mon, Jan 5
LAX
Los Angeles
FLO
Florence
$571 Roundtrip, found 18 hours ago
$571
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Mon, Jan 5, priced at $571 found 18 hours ago
Wed, Dec 31 - Sun, Jan 4
LAX
Los Angeles
FLO
Florence
$580 Roundtrip, found 18 hours ago
$580
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Los Angeles to Florence, returning Sun, Jan 4, priced at $580 found 18 hours ago
Fri, Jan 2 - Mon, Jan 5
LAX
Los Angeles
FLO
Florence
$581 Roundtrip, found 18 hours ago
$581
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Mon, Jan 5, priced at $581 found 18 hours ago
Fri, Jan 2 - Mon, Jan 5
LAX
Los Angeles
FLO
Florence
$595 Roundtrip, found 18 hours ago
$595
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Mon, Jan 5, priced at $595 found 18 hours ago
Fri, Jan 2 - Mon, Jan 5
LAX
Los Angeles
FLO
Florence
$599 Roundtrip, found 18 hours ago
$599
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Mon, Jan 5, priced at $599 found 18 hours ago
Fri, Jan 2 - Mon, Jan 5
LAX
Los Angeles
FLO
Florence
$617 Roundtrip, found 18 hours ago
$617
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Mon, Jan 5, priced at $617 found 18 hours ago
Fri, Jan 2 - Sat, Jan 3
LAX
Los Angeles
FLO
Florence
$621 Roundtrip, found 18 hours ago
$621
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Sat, Jan 3, priced at $621 found 18 hours ago
Fri, Jan 2 - Mon, Jan 5
LAX
Los Angeles
FLO
Florence
$622 Roundtrip, found 18 hours ago
$622
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Fri, Jan 2 from Los Angeles to Florence, returning Mon, Jan 5, priced at $622 found 18 hours ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence, Florence, SC
$100 nightly
The price is $112 total per night from Nov 17 to Nov 18
$112 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,002 reviews)
Everything was great. The room were clean and staff was courteous.

Reviewed on Nov 2, 2025

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St, Florence, SC
$130 nightly
The price is $146 total per night from Nov 16 to Nov 17
$146 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this 3-star spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (593 reviews)
We did not eat there but we had a good nights sleep! Very comfy and clean. A cool hotel!

Reviewed on Nov 6, 2025

Hotel Florence, Tapestry Collection by Hilton
Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown

2 out of 5
415 S. IRBY ST, Florence, SC
Stay at this hotel in Florence. Enjoy free WiFi. Popular attractions Drs Bruce and Lee Foundation Library and Florence Museum are located nearby.
6/10 (2 reviews)
Good

Reviewed on Oct 3, 2025

Get rates
Rodeway Inn Florence Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
$95 nightly
The price is $106 total per night from Dec 7 to Dec 8
$106 total
Dec 7 - Dec 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,183 reviews)
Room was comfortable. I didn't utilize the breakfast

Reviewed on Nov 8, 2025

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
$65 nightly
The price is $73 total per night from Nov 12 to Nov 13
$73 total
Nov 12 - Nov 13
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,425 reviews)
Everything was perfect!! I've stayed at this HoJo's before. The staff are great!! Clean breakfast area, very nice!!

Reviewed on Nov 8, 2025

Howard Johnson by Wyndham Florence
Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
527 Woody Jones Blvd, Florence, SC
$103 nightly
The price is $116 total per night from Nov 30 to Dec 1
$116 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,135 reviews)
Yes

Reviewed on Nov 2, 2025

Comfort Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard, Florence, SC
$56 nightly
The price is $63 total per night from Nov 12 to Nov 13
$63 total
Nov 12 - Nov 13
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,005 reviews)
Pam at the front desk was very friendly and helpful! The room wasn’t exactly the cleanest. However the customer service was spectacular!

Reviewed on Nov 3, 2025

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway, Timmonsville, SC
$61 nightly
The price is $68 total per night from Nov 10 to Nov 11
$68 total
Nov 10 - Nov 11
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (319 reviews)
very clean

Reviewed on Oct 16, 2025

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr, Florence, SC
$61 nightly
The price is $68 total per night from Nov 10 to Nov 11
$68 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,001 reviews)
Spotless and comfortable room. Staff was friendly and helpful.

Reviewed on Nov 6, 2025

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd, Florence, SC
$103 nightly
The price is $116 total per night from Nov 16 to Nov 17
$116 total
Nov 16 - Nov 17
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,014 reviews)
The front desk service was top notch as she assisted me with getting my reservation corrected that Hotel.com messed up.

Reviewed on Nov 2, 2025

Home2 Suites by Hilton Florence, SC
Baymont Inn & Suites Florence by Wyndham

Baymont Inn & Suites Florence by Wyndham

2.5 out of 5
1826 W Lucas Street, Florence, SC
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Dr. Eddie Floyd Tennis Center ...
I made a reservation in February for Labor Day weekend reserved 3 rooms of 2 beds and pull out sofa bed. Was told that only 2 of those rooms exist at this location. Then said Nevermind we do have that. They planned on putting a mattress on the floor of a king room that they were in the process of ...

Reviewed on Sep 4, 2024

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Baymont Inn & Suites Florence by Wyndham
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd, Florence, SC
$95 nightly
The price is $106 total per night from Nov 16 to Nov 17
$106 total
Nov 16 - Nov 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (12 reviews)
Everything was wonderful. My only suggestion is to put an area rug where the sofa and table are located. With no carpet in the room it echos to much.

Reviewed on Sep 5, 2025

Spark by Hilton Florence North I-95, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

LAX to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
LAX Address & GPS
Address:
One World Way
Los Angeles CA, 90045-5803
United States
IATA Code:
LAX
Longitude:
-118.408279
Latitude:
33.943399
Time Zone:
America/Los_Angeles
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York

Frequently asked questions

What is the shortest flight from LAX to FLO?
Take the opportunity to kick back and unwind on the flight from Los Angeles to Florence. The quickest flight time from LAX to FLO is 5 hours and 36 minutes, which gives you lots of time to indulge in a tipple or get engrossed in a book.
How many hours flight from LAX to Florence Regional Airport (FLO)?
The flight from LAX to FLO takes an average of 5 hours and 47 minutes. A couple of movies, a gripping novel and a nice snooze will make the time zip by.
What airlines have the most flights from LAX to FLO?
For now, there aren't any direct flights from LAX to FLO. However, you will be able to book a flight with at least one stop. Look on the positive side — use the time to stretch your travel-weary legs or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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