Cheap flights from LAX to FLO (Los Angeles Intl. to Florence Regional)

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Cheap Flights from LAX to FLO starting at $283 One Way, Round Trip

Prices starting at for return flights and $283 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$110 nightly
The price is $123 total per night from Oct 1 to Oct 2
$123 total
Oct 1 - Oct 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,011 reviews)
"A wonderful place to stay with really good breakfast!!!"

Reviewed on Sep 1, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$139 nightly
The price is $155 total per night from Sep 11 to Sep 12
$155 total
Sep 11 - Sep 12
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (653 reviews)
"The hotel was beautiful. It was quaint and it had two different bars. One was a guitar bar where you could have appetizers and drink and the other was a four-star restaurant that was absolutely awesome. We ate there each night and had a totally different meal each night. The bartenders were friendly ..."

Reviewed on Aug 31, 2026

Hotel Florence, Tapestry Collection by Hilton
Cozy & Inviting

Cozy & Inviting

Florence SC
Stay at this apartment in Florence. Enjoy air conditioning. Popular attractions Florence County Museum and FMU Performing Arts Center are located nearby.
Get rates
Cozy & Inviting
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 out of 5
150 Dunbarton Dr Florence SC
$88 nightly
The price is $98 total per night from Sep 30 to Oct 1
$98 total
Sep 30 - Oct 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (352 reviews)
"This hotel needs an update and some cleaning. Rooms were dirty, hair all over bathroom, pillows with just a pillow case, no cover, pillows were stained. Bed linens had cigarette burn holes and rooms smelled like cigarettes and pot. Pool looked gross."

Reviewed on Aug 31, 2026

Quality Inn & Suites Florence Civic Center
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$80 nightly
The price is $89 total per night from Sep 7 to Sep 8
$89 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,417 reviews)
"Excellent hotel for the price - clean, modern, comfortable, safe and great bed and bedding."

Reviewed on Sep 1, 2026

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$65 nightly
The price is $72 total per night from Sep 3 to Sep 4
$72 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,711 reviews)
"The hotel was clean and functional. Front desk was very welcoming and helpful. Could have been more offerings on the breakfast “buffet”."

Reviewed on Sep 1, 2026

Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Oct 1 to Oct 2
$63 total
Oct 1 - Oct 2
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,002 reviews)
"very clean"

Reviewed on Aug 18, 2026

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Sep 2 to Sep 3
$68 total
Sep 2 - Sep 3
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$64 nightly
The price is $72 total per night from Sep 21 to Sep 22
$72 total
Sep 21 - Sep 22
Total with taxes and fees
Enjoy free breakfast, free WiFi, and free parking.
7.2/10 Good! (1,000 reviews)
"Pool was closed for repairs, laundry room was too dirty for me to use, property was touted as renovated. More like a coat of paint on everything broken."

Reviewed on Sep 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$104 nightly
The price is $117 total per night from Sep 27 to Sep 28
$117 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$97 nightly
The price is $109 total per night from Sep 7 to Sep 8
$109 total
Sep 7 - Sep 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$64 nightly
The price is $72 total per night from Sep 21 to Sep 22
$72 total
Sep 21 - Sep 22
Total with taxes and fees
Enjoy free breakfast, free WiFi, and free parking.
7.2/10 Good! (1,000 reviews)
"Pool was closed for repairs, laundry room was too dirty for me to use, property was touted as renovated. More like a coat of paint on everything broken."

Reviewed on Sep 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

LAX to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from LAX to FLO?
Take the opportunity to kick back and unwind on the flight from Los Angeles to Florence. The quickest flight time from LAX to FLO is 5 hours and 36 minutes, which gives you lots of time to indulge in a tipple or get engrossed in a book.
How many hours flight from LAX to Florence Regional Airport (FLO)?
The flight from LAX to FLO takes an average of 5 hours and 47 minutes. A couple of movies, a gripping novel and a nice snooze will make the time zip by.
What airlines have the most flights from LAX to FLO?
For now, there aren't any direct flights from LAX to FLO. However, you will be able to book a flight with at least one stop. Look on the positive side — use the time to stretch your travel-weary legs or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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