
$126 Cheap flight deals from Des Moines (DSM) to Amherst (BUF)
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Airfares from $126 One Way, $255 Round Trip from Des Moines to Amherst
Prices starting at $255 for return flights and $126 for one-way flights to Amherst were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Amherst economy flight packages

Holiday Inn Express Grand Island - Niagara Falls by IHG
Nov 15 - Nov 18
Des Moines (DSM) to Buffalo (BUF)
Reviewed on Oct 5, 2025

Niagara Crossing Hotel & Spa
Nov 15 - Nov 18
Des Moines (DSM) to Buffalo (BUF)
Reviewed on Aug 31, 2025

Buffalo Airport Hotel
Nov 15 - Nov 17
Des Moines (DSM) to Buffalo (BUF)
Buffalo (BUF) to Des Moines (DSM)
Reviewed on Aug 30, 2025
More About Flying To Amherst from Des Moines
Route Information for Flights from Des Moines to Amherst
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | BUF |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Amherst
Great Deals on Flights From Des Moines to Amherst
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Flights That Fit Your Budget
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Flights from Des Moines
- Des Moines to Houston
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Des Moines Airports
Amherst Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.