
$275 Cheap flight deals from San Antonio (SAT) to Medellin (MDE)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from San Antonio to Medellin
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $275 One Way, $424 Round Trip from San Antonio to Medellin
Prices starting at $424 for return flights and $275 for one-way flights to Medellin were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Medellin economy flight packages

Hotel Park 10
Jun 6 - Jun 10
San Antonio (SAT) to Medellín (MDE)
Reviewed on Oct 27, 2025

Diez Hotel Categoria Colombia
Jun 6 - Jun 10
San Antonio (SAT) to Medellín (MDE)
Reviewed on May 24, 2024

Hotel Lagoon
Jun 6 - Jun 10
San Antonio (SAT) to Medellín (MDE)
Reviewed on Dec 28, 2022
More About Flying To Medellin from San Antonio
Route Information for Flights from San Antonio to Medellin
Origin Airport IATA Code | SAT |
|---|---|
Destination Airport IATA Code | MDE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
San Antonio to Medellin
It can be tedious to sift through pages of Internet search results to find those bargain fares on flights from San Antonio to Medellin and hotels, but at Orbitz, everything you need is in one place. Our guaranteed low prices on San Antonio to Medellin flights mean we are a leader when it comes to giving you great online deals on air fare and hotels.
Huge savings with little effort
Whether you are traveling for pleasure or business, you can use Orbitz to find cheap San Antonio to Medellin flights, together with low-cost accommodations. We pride ourselves on offering you excellent deals that fit your schedule and budget needs.
Unbeatable low fare flights from San Antonio to Medellin
Domestic or international travel presents no obstacles to us. We give you unbeatable bargains on flights from San Antonio to Medellin. Enjoy huge savings on your flight, which can be better used elsewhere on your trip.
Grab that cheap deal on the move
Our innovative and cutting-edge mobile tools make it easy to search or booking cheap flights from San Antonio to Medellin while on the move, via our app for the iPhone, iPad, or Android-based devices. We can also send you instant alerts through email or text messaging if there any delays to your flight.
Orbitz means low-cost trip-planning made easy
Low-cost San Antonio to Medellin flights can be booked with total confidence through Orbitz every time. We also make it very easy to cancel flights or other travel arrangements online should you need to. You can also add activities and car rentals to your flight or hotel reservation for a hassle-free trip.
Frequently asked questions
Flights to Medellin
- New York to Medellin
- Toronto to Medellin
- Los Angeles to Medellin
- Orlando to Medellin
- Houston to Medellin
- Chicago to Medellin
- Bogotá to Medellin
- Montreal to Medellin
- San Francisco to Medellin
- Pereira to Medellin
- Barranquilla to Medellin
- Buenos Aires to Medellin
- Sao Paulo to Medellin
- Bucaramanga to Medellin
Flights from San Antonio
- San Antonio to Chicago
- San Antonio to Dallas
- San Antonio to Los Angeles
- San Antonio to New York
- San Antonio to Houston
- San Antonio to Orlando
- San Antonio to Atlanta
- San Antonio to New Orleans
- San Antonio to Washington
- San Antonio to Sacramento
- San Antonio to Detroit
- San Antonio to San Francisco
- San Antonio to London
- San Antonio to Kansas City
- San Antonio to Toronto
- San Antonio to Rome
- San Antonio to Hartford
- San Antonio to Harrisburg - Hershey
- San Antonio to Seoul
- San Antonio to Shanghai
San Antonio Airports
Medellin Airports
More Destinations
- Hotels near Arvi Park
- Cabin Rentals in Guarne
- Guarne Hotels
- San Antonio de Prado Hotels
- Hotels with Free Airport Shuttle in Medellín
- Extended Stay Hotels in San Antonio de Pereira
- San Antonio de Pereira Hotels
- Amaga Hotels
- Apartments in Bello
- Farmstay in Retiro
- Retiro Hotels
- Hotels near Hospital Universitario San Vicente de Paul
- Hotels near Medellín Clinic - El Poblado
- Hotels near Atanasio Giradot Stadium
- Cabin Rentals in Rionegro
- Rionegro Hotels
- Villas in Rionegro
- Girardota Hotels
- Hotels near José María Córdova Intl.
- Manrique Hotels
- Hotels near Golden Mile
- Business Hotels in Antioquia
- Kid Friendly Hotels in Antioquia
- Hotels with Hot Tubs in Antioquia
- Pet Friendly Hotels in Antioquia
- Spa Resorts & in Antioquia
- Hotels with a Wedding Venue in Antioquia
- Antioquia Hotels
- Cabin Rentals in San Jerónimo
- San Jerónimo Hotels
- Villas in San Jerónimo
- Extended Stay Hotels in Santa Elena
- Cottages in Itagüí
- Extended Stay Hotels in Itagüí
- Itagüí Hotels
- Hotels near Lleras Park
- Hotels near Llanogrande Mall
- El Rosario Hotels
- Hotels near Piedras Blancas Ecological Park
- Marinilla Hotels
- San Javier Hotels
- Hotels near Hospital Pablo Tobon Uribe
- San Diego Hotels
- Cheap Hotels in El Poblado
- Kid Friendly Hotels in El Poblado
- Gay Friendly Hotels in El Poblado
- Hotels with Balconies in El Poblado
- Hotels with an Indoor Pool in El Poblado
- Hotels with a Wedding Venue in El Poblado
- El Poblado Hotels
- La Candelaria Hotels
- Hotels near Botero Plaza
- Hotels near Explora Park
- Condo Rentals in Envigado
- Guest Houses in Envigado
- Envigado Hotels
- Estadio Hotels
- Spa Resorts & in Laureles
- Apartments in Sabaneta
- Condo Rentals in Sabaneta
- Cottages in Sabaneta
- Sabaneta Hotels
- Flights from Bello
- Flights to Rionegro
- Flights from New York to Rionegro
- Flights from Rionegro
- Flights from José María Córdova Intl.
- Flights from Bogotá (BOG) to Medellín (MDE)
- Flights from New York (JFK) to Medellín (MDE)
- Flights from Los Angeles (LAX) to Medellín (MDE)
- Flights from Miami (MIA) to Medellín (MDE)
- Flights to Antioquia
- Flights from Santa Elena
- Flights from Bogotá to Guatapé
- Flights from Buenos Aires to Guatapé
- Flights from Dallas to Guatapé
- Flights from Minneapolis - St. Paul to Guatapé
- Flights from St. Louis to Guatapé
- Flights from Fort Lauderdale to Guatapé
- Flights from Tampa to Guatapé
- Flights from Cali to Guatapé
- Flights from Itagüí
- Flights from Envigado
- Car rentals near Plaza Cisneros
- Car rental Rionegro
- Alamo Rent A Car Rental Cars in José María Córdova Intl.
- Avis Rental Cars in José María Córdova Intl.
- Budget Rental Cars in José María Córdova Intl.
- Dollar Rent A Car Rental Cars in José María Córdova Intl.
- Enterprise Rental Cars in José María Córdova Intl.
- Europcar Rental Cars in José María Córdova Intl.
- Fox Rental Cars Rental Cars in José María Córdova Intl.
- Hertz Rental Cars in José María Córdova Intl.
- Payless Rental Cars in José María Córdova Intl.
- Car rentals near Antioquia
- Car rental Sabaneta
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


