$323 Cheap flight deals from San Antonio (SAT) to Medellín (MDE)

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This Weekend's Flight Deals from San Antonio to Medellín

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 21 - Sat, Aug 29
SAT
San Antonio Intl.
MDE
José María Córdova Intl.
$976 Roundtrip, found 2 days ago
$976
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Fri, Aug 21 from San Antonio Intl. to José María Córdova Intl., returning Sat, Aug 29, priced at $976 found 2 days ago

Airfares from $323 One Way, $606 Round Trip from San Antonio to Medellín

Prices starting at $606 for return flights and $323 for one-way flights to Medellín were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jun 20 - Mon, Jun 28
SAT
San Antonio
MDE
Medellín
$606 Roundtrip, found 2 days ago
$606
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jun 20 from San Antonio to Medellín, returning Mon, Jun 28, priced at $606 found 2 days ago
Sun, Jun 20 - Mon, Jun 28
SAT
San Antonio
MDE
Medellín
$656 Roundtrip, found 2 days ago
$656
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jun 20 from San Antonio to Medellín, returning Mon, Jun 28, priced at $656 found 2 days ago
Sun, Jun 20 - Mon, Jun 28
SAT
San Antonio
MDE
Medellín
$675 Roundtrip, found 2 days ago
$675
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jun 20 from San Antonio to Medellín, returning Mon, Jun 28, priced at $675 found 2 days ago
Sun, Jun 20 - Mon, Jun 28
SAT
San Antonio
MDE
Medellín
$678 Roundtrip, found 2 days ago
$678
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jun 20 from San Antonio to Medellín, returning Mon, Jun 28, priced at $678 found 2 days ago
Sun, Mar 21 - Thu, Mar 25
SAT
San Antonio
MDE
Medellín
$697 Roundtrip, found 5 days ago
$697
Roundtrip
found 5 days ago
Select United flight, departing Sun, Mar 21 from San Antonio to Medellín, returning Thu, Mar 25, priced at $697 found 5 days ago

Medellín economy flight packages

Price found within the past 48 hours. Click for updated prices.
Autenthico Provenza Hotel Medellin
2.0-star property

Autenthico Provenza Hotel Medellin

8/10 Very Good! (19 reviews)

Oct 6 - Oct 12

6 night stay

San Antonio (SAT) to Medellín (MDE)

American Airlines • Non-stop • Coach

Medellín (MDE) to San Antonio (SAT)

Avianca • Non-stop • Coach
Price was $1,692, price is now $1,241 per person
$1,241
per person
found 24 hours ago

BoH Collection
3.0-star property

BoH Collection

9.6/10 Exceptional! (5 reviews)

Oct 6 - Oct 12

6 night stay

San Antonio (SAT) to Medellín (MDE)

American Airlines • Non-stop • Coach

Medellín (MDE) to San Antonio (SAT)

Avianca • Non-stop • Coach
Price was $2,628, price is now $1,818 per person
$1,818
per person
found 24 hours ago
My stay was amazing but for two things. The staff was great. Reception didn't speak English, but my Spanish and their patience worked. The wait staff in the restaurant was friendly in a way that felt genuine and authentic. I am bad with names so I felt well received and cared for by an olive complexioned man at reception with jet black hair. The tallest male server... and Andrea (who's name I do remember) on the waitstaff were stand outs. 1) The construction of the building allows for sound to bounce around when people are waiting on the elevator and chatting. I would have been better served on a higher floor than being on the same floor as the lobby. I was privy to the conversations had there. 2) I must tell you that the room is very modern. There is square basin with a raised stone deck. Curious as to how it was situated, I lifted the deck to find mold. I immediately asked the manager to have it cleaned while I was out for the day. He was very responsive and also had housekeeping tidy the bed--which I didn't need them to do. It was nice that they did. There were no chemical odors when I returned. Otherwise, the room was impressive. The A/C was well placed, the layout was just like the photo online. They attend to all of your senses with adjustable lighting, a light scent humidifier near the beds, and the bed was comfortable and the shower was hot. Overall, I enjoyed my stay, felt well attended, enjoyed the whimsy of "los patos." I'd stay again.

Reviewed on Aug 9, 2026

Blues Suites Medellin
4.0-star property

Blues Suites Medellin

9/10 Wonderful! (1,288 reviews)

Oct 6 - Oct 12

6 night stay

San Antonio (SAT) to Medellín (MDE)

American Airlines • Non-stop • Coach

Medellín (MDE) to San Antonio (SAT)

Avianca • Non-stop • Coach
Price was $1,735, price is now $1,259 per person
$1,259
per person
found 24 hours ago

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More About Flying To Medellín from San Antonio

Route Information for Flights from San Antonio to Medellín

Origin Airport IATA Code
SAT
Destination Airport IATA Code
MDE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

San Antonio to Medellín

When you’re searching for San Antonio to Medellín flights for your family vacation, check out the guaranteed low prices at Orbitz. If you are looking for the best prices on hotels too, you’ll be sure to find great deals to suit your budget. You’ll also benefit from the following features:

Suitable Schedules

Orbitz simplifies the process of finding and booking budget flights from San Antonio to Medellín. Since we monitor hundreds of flight fares, you can compare several flights from a range of different airlines to find the best fares and most suitable departure and arrival times. Mix and match your departure and return flight for even more discounts and travel flexibility.

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Flight Alerts

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Miles and Points

If you travel regularly, you can still earn miles and points when you book qualifying San Antonio to Medellín flights. Enter your frequent flyer number with your reservation to see the miles rack up.

Frequently asked questions

What is the shortest flight from San Antonio to Medellin?
The quickest flight time from San Antonio to Medellin is around 6 hours and 9 minutes. Grab a wine from the cabin crew, work on your travel itinerary or get to know your neighbors — you'll have enough time on this medium-haul journey.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.