$53 Cheap flight deals from Chicago (CHI) to Eastern Louisiana (MSY)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Chicago to Eastern Louisiana

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 15 - Mon, Aug 18
ORD
O'Hare Intl.
MSY
Louis Armstrong New Orleans Intl.
$200 Roundtrip, just found
$200
Roundtrip
just found
Select Spirit Airlines flight, departing Fri, Aug 15 from O'Hare Intl. to Louis Armstrong New Orleans Intl., returning Mon, Aug 18, priced at $200 just found
Sat, Aug 16 - Mon, Aug 18
MDW
Midway Intl.
MSY
Louis Armstrong New Orleans Intl.
$221 Roundtrip, found 5 days ago
$221
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sat, Aug 16 from Midway Intl. to Louis Armstrong New Orleans Intl., returning Mon, Aug 18, priced at $221 found 5 days ago
Fri, Aug 15 - Fri, Aug 22
ORD
O'Hare Intl.
LFT
Lafayette Regional
$288 Roundtrip, found 5 days ago
$288
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Aug 15 from O'Hare Intl. to Lafayette Regional, returning Fri, Aug 22, priced at $288 found 5 days ago
Sat, Aug 16 - Fri, Aug 22
ORD
O'Hare Intl.
BTR
Baton Rouge Metropolitan
$289 Roundtrip, found 3 days ago
$289
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Aug 16 from O'Hare Intl. to Baton Rouge Metropolitan, returning Fri, Aug 22, priced at $289 found 3 days ago

Airfares from $53 One Way, $137 Round Trip from Chicago to Eastern Louisiana

Prices starting at $137 for return flights and $53 for one-way flights to Eastern Louisiana were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 5 - Sat, Nov 8
MDW
Chicago
MSY
New Orleans
$137 Roundtrip, found 4 days ago
$137
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Nov 5 from Chicago to New Orleans, returning Sat, Nov 8, priced at $137 found 4 days ago
Sat, Oct 25 - Tue, Oct 28
ORD
Chicago
MSY
New Orleans
$149 Roundtrip, found 2 hours ago
$149
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 25 from Chicago to New Orleans, returning Tue, Oct 28, priced at $149 found 2 hours ago
Sat, Oct 18 - Wed, Oct 22
ORD
Chicago
MSY
New Orleans
$154 Roundtrip, found 14 hours ago
$154
Roundtrip
found 14 hours ago
Select United flight, departing Sat, Oct 18 from Chicago to New Orleans, returning Wed, Oct 22, priced at $154 found 14 hours ago
Thu, Oct 16 - Mon, Oct 20
MDW
Chicago
MSY
New Orleans
$180 Roundtrip, found 3 days ago
$180
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Oct 16 from Chicago to New Orleans, returning Mon, Oct 20, priced at $180 found 3 days ago
Fri, Oct 31 - Mon, Nov 3
ORD
Chicago
BTR
Baton Rouge
$224 Roundtrip, found 6 days ago
$224
Roundtrip
found 6 days ago
Select United flight, departing Fri, Oct 31 from Chicago to Baton Rouge, returning Mon, Nov 3, priced at $224 found 6 days ago

Eastern Louisiana economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Barnett, part of JdV by Hyatt
4.0-star property

The Barnett, part of JdV by Hyatt

8.8/10 Excellent! (1,008 reviews)

Sep 12 - Sep 14

2 night stay

Chicago (CHI) to New Orleans (MSY)

Spirit Airlines • Coach

New Orleans (MSY) to Chicago (CHI)

Southwest Airlines • Coach
per person
found 1 day ago
Spent the Independence Day holiday at The Barnett and had an amazing stay. The staff was so friendly and welcoming, and the property was spotless. The restored art deco building is beautiful, and the rooms are modern, spacious, and comfortable. I loved the rooftop pool with cocktails and great city views. With excellent dining options and spaces that work for both relaxing and getting things done, it’s the perfect mix of New Orleans charm and comfort. Highly recommend!

Reviewed on Jul 6, 2025

Hotel Perle
4.5-star property

Hotel Perle

10/10 Exceptional! (31 reviews)

Sep 12 - Sep 14

2 night stay

Chicago (CHI) to New Orleans (MSY)

Southwest Airlines • Roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
I came to NOLA for a girls trip for my 50th birthday and Hotel Perle was absolutely perfect! The decor was a classy New Orleans style, very clean, safe neighborhood, and had many options for dining that were walkable. It was in a nice quiet area away from the hustle and bustle of the French Quarter, but an easy walk to get to those areas. We really liked that all of us could have separate rooms, but then a spacious area to relax and have conversation. The rooftop pool area was also a fabulous spot to take a break after sightseeing. I cannot recommend this place enough and I would definitely stay here again.

Reviewed on Jul 1, 2025

Hotel Saint Vincent
4.5-star property

Hotel Saint Vincent

9.6/10 Exceptional! (124 reviews)

Sep 12 - Sep 14

2 night stay

Chicago (CHI) to New Orleans (MSY)

Southwest Airlines • Roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
Don't see what you're looking for?
See all available trips from Chicago to Eastern Louisiana
View all trips

Eastern Louisiana packages with premium economy flights

Price found within the past 48 hours. Click for updated prices.
Wyndham New Orleans - French Quarter
4.0-star property

Wyndham New Orleans - French Quarter

8.6/10 Excellent! (4,340 reviews)

Sep 11 - Sep 14

3 night stay

Chicago (ORD) to New Orleans (MSY)

Delta • Non-stop roundtrip • PremiumEconomy
per person
found 1 day ago
It was located close to bourbon st

Reviewed on Aug 6, 2025

Hilton New Orleans Riverside
4.0-star property

Hilton New Orleans Riverside

8.8/10 Excellent! (1,145 reviews)

Sep 11 - Sep 14

3 night stay

Chicago (ORD) to New Orleans (MSY)

Delta • Non-stop roundtrip • PremiumEconomy
per person
found 1 day ago
I had an amazing stay at the Hilton. The staff were so nice and accommodating. I would definitely stay here again. Drago’s the restaurant was so good.

Reviewed on May 27, 2025

Maison Dupuy Hotel
3.5-star property

Maison Dupuy Hotel

7.8/10 Good! (2,379 reviews)

Sep 11 - Sep 14

3 night stay

Chicago (ORD) to New Orleans (MSY)

Delta • Non-stop roundtrip • PremiumEconomy
per person
found 1 day ago
Very friendly staff, especially the front desk! Loved the balcony with pool views!

Reviewed on Mar 17, 2025

Don't see what you're looking for?
See all available trips from Chicago to Eastern Louisiana
View all trips

More About Flying To Eastern Louisiana from Chicago

Route Information for Flights from Chicago to Eastern Louisiana

Origin Airport IATA Code
CHI
Destination Airport IATA Code
MSY
Distance
838 mi
Direct Flight Airlines
American Airlines, Qatar Airways, JAL, Air Canada, Copa Airlines, Air New Zealand, United Airlines, Alaska Airlines, Cathay Pacific, Qantas, Turkish Airlines, Finnair, ANA, Lufthansa, Spirit Airlines, British Airways, Gulf Air
Earliest Flight Arrival
2:48PM UTC
Latest Flight Arrival
4:23AM UTC

Chicago to Eastern Louisiana

Score low fares on flights from Chicago to Eastern Louisiana with Orbitz. We make it easier than ever to find cheap Chicago to Eastern Louisiana flights with our cutting-edge mobile tools and mobile website.

Book Discount Flights From Chicago to Eastern Louisiana in Minutes

If you are looking for low cost Chicago to Eastern Louisiana flights, just skip all of the other so-called bargain travel sites, because Orbitz offers guaranteed low fares. That means you don't have to constantly scan multiple sites and hover like a vulture at your computer, hoping to score better deals through last-minute sales.

Find Bargain Chicago to Eastern Louisiana Flights With Our Convenient Tools

You benefit from more than just cheap flights from Chicago to Eastern Louisiana. Orbitz is a convenient one-stop trip planner. Research weather, attractions, and transportation options for Eastern Louisiana to help you plan your trip and decide what to pack and where to go.

Booking domestic or international air fare and accommodations with Orbitz is a snap. Use your iPad, iPhone or Android device to find discount flights from Chicago to Eastern Louisiana even while on the move, and sign up for instant email and text alerts to stay up-to-date on any delays affecting your flight. Or access m.orbitz.com via your mobile device’s Web browser.

Earn Miles through Orbitz for Your Frequent Flyer Program

You don't have to give up frequent flyer points to take advantage of our low fares. Add your frequent flyer number when you book your Chicago to Eastern Louisiana flights to receive credit for your trip.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.