Hotels in Otay Mesa

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Nov 9 - Nov 10
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Check prices in Otay Mesa for tonight, Nov 9 - Nov 10
Nov 10 - Nov 11
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Check prices in Otay Mesa for tomorrow night, Nov 10 - Nov 11

Featured Hotels in Otay Mesa

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
14.9 mi from Otay Mesa
$229 nightly
The price is $265 total per night
$265 total
Nov 23 - Nov 24
Total with taxes and fees
Hard Rock Hotel San Diego features a nightclub, an outdoor pool, and a 24-hour gym. Valet parking is offered for USD 65 per night. Multilingual staff at the 24-hour front desk can assist with concierge services, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and conference space.
Pool
Free WiFi
Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
14.98 mi from Otay Mesa
$295 nightly
The price is $342 total per night
$342 total
Nov 30 - Dec 1
Total with taxes and fees
At Pendry San Diego, guests enjoy a full-service spa, an outdoor pool, and a 24-hour gym. Valet parking is available for USD 65 per night. The front desk is staffed 24/7 to help with luggage storage, tours or tickets, and securing valuables. Other amenities at this luxury hotel include a rooftop terrace, free WiFi in public areas, and a hot tub.
Pool
Hot Tub
InterContinental San Diego by IHG

InterContinental San Diego by IHG

4 out of 5
901 Bayfront Court, San Diego, CA
Free Cancellation
15.83 mi from Otay Mesa
$262 nightly
The price is $304 total per night
$304 total
Nov 22 - Nov 23
Total with taxes and fees
At InterContinental San Diego by IHG, guests enjoy features like an outdoor pool, a 24-hour gym, and a rooftop terrace. Valet parking is available for USD 66 per day. Multilingual staff at the 24-hour front desk can assist with concierge services, dry cleaning/laundry, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls and an off-leash area. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Pet friendly
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St, San Diego, CA
Free Cancellation
15.84 mi from Otay Mesa
$114 nightly
The price is $132 total per night
$132 total
Nov 27 - Nov 28
Total with taxes and fees
Guests of Courtyard by Marriott San Diego Downtown Little Italy have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 40 per day. The front desk has multilingual staff on hand 24/7 to help with concierge services, securing valuables, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include a living plant wall, an ATM, and a gift shop.
Pool
Pet friendly
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.97 mi from Otay Mesa
$160 nightly
The price is $186 total per night
$186 total
Nov 23 - Nov 24
Total with taxes and fees
Guests of Wyndham San Diego Bayside have access to an outdoor pool, a gym, and free WiFi in public areas. If you drive, self parking is USD 50.00 per night, or you can take advantage of the free airport shuttle at scheduled times. Multilingual staff at the 24-hour front desk can assist with securing valuables, tours or tickets, and luggage storage. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Free airport shuttle
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
17.66 mi from Otay Mesa
$114 nightly
The price is $131 total per night
$131 total
Nov 16 - Nov 17
Total with taxes and fees
At Hilton San Diego Mission Valley, guests enjoy features like an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 37 per day. The 24-hour front desk has staff standing by to help with concierge services, dry cleaning/laundry, and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
17.93 mi from Otay Mesa
$143 nightly
The price is $164 total per night
$164 total
Nov 10 - Nov 11
Total with taxes and fees
Guests of Legacy Resort Hotel & Spa enjoy a full-service spa, an outdoor pool, and a gym. Self parking is offered for USD 35 per night. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and concierge services. Other amenities at this spa hotel include a sauna, free WiFi in public areas, and a hot tub.
Pool
Hot Tub
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.06 mi from Otay Mesa
$109 nightly
The price is $125 total per night
$125 total
Dec 1 - Dec 2
Total with taxes and fees
At Handlery Hotel, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 24 per night. The 24-hour front desk has multilingual staff ready to assist with luggage storage, concierge services, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub
Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

3 out of 5
3888 Greenwood St, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
19.11 mi from Otay Mesa
$119 nightly
The price is $137 total per night
$137 total
Nov 16 - Nov 17
Total with taxes and fees
At Hampton Inn & Suites by Hilton San Diego SeaWorld, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 25 per day. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a hot tub, laundry facilities, and a garden.
Pool
Hot Tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa Hotels

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Otay Mesa hotels essential information

Accommodation
4,839 hotels
Lowest Price
$125
Highest Price
$342
Popular hotels
Hilton San Diego Mission Valley, Hampton Inn & Suites by Hilton San Diego SeaWorld, Pendry San Diego, Hard Rock Hotel San Diego, Courtyard by Marriott San Diego Downtown Little Italy, InterContinental San Diego by IHG, Legacy Resort Hotel & Spa, Handlery Hotel, Wyndham San Diego Bayside

Popular places to visit

San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

4.5/5(3,565 reviews)

Why not visit the animals who live at San Diego Zoo and see why this is a favorite attraction in San Diego? Stroll along the area's seaside or experience its acclaimed art scene.

See properties in San Diego Zoo
San Diego Zoo
San Diego Convention Center

San Diego Convention Center

4.5/5(1,297 reviews)

During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's acclaimed art scene and entertainment choices.

See properties in San Diego Convention Center
San Diego Convention Center
Mission Bay featuring a sandy beach

Mission Bay

4.5/5(2,386 reviews)

Explore the great outdoors at Mission Bay, a popular spot to commune with nature in San Diego. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.

See properties in Mission Bay
Mission Bay

Recent Reviews

InterContinental San Diego by IHG

InterContinental San Diego by IHG

5/5 Excellent
"Front desk staff were efficient, polite and helpful. The room was very clean - spotless and very comfortable. Absolutely loved dining at the in house restaurant, Garibaldi's! They're featuring an amazing new Mediterranean based menu that made for one of the best meals my wife and I have ever enjoyed. We loved our stay! "
A verified traveler stayed at InterContinental San Diego by IHG
Posted 2 days ago
InterContinental San Diego by IHG

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