Hotels in Otay Mesa
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Featured Hotels in Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct San Diego CA
Free Cancellation
1.96 mi from Otay Mesa
$154 nightly
The price is $175 total per night
$175 total
Jun 30 - Jul 1
Total with taxes and fees
Guests staying at Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG enjoy an outdoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a business center, a meeting room, and a computer station.

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Free Cancellation
Reserve now, pay when you stay
14.9 mi from Otay Mesa
$225 nightly
The price is $261 total per night
$261 total
Jun 30 - Jul 1
Total with taxes and fees
Hard Rock Hotel San Diego features a nightclub, an outdoor pool, and a 24-hour gym. Valet parking is offered for USD 70 per night. Multilingual staff at the 24-hour front desk can assist with securing valuables, luggage storage, and concierge services. Additional amenities include free WiFi in public areas, meeting rooms, and conference space.
Pool
Free WiFi

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
Free Cancellation
Reserve now, pay when you stay
15.38 mi from Otay Mesa
$286 nightly
The price is $332 total per night
$332 total
Jul 5 - Jul 6
Total with taxes and fees
Guests staying at Manchester Grand Hyatt San Diego enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 65 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, tours or tickets, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free Cancellation
Reserve now, pay when you stay
15.76 mi from Otay Mesa
$119 nightly
The price is $138 total per night
$138 total
Jun 30 - Jul 1
Total with taxes and fees
Guests of The DEXTRO Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 45.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and tours/tickets. Additional amenities include meeting rooms, conference space, and a 24-hour business center.

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
Free Cancellation
Reserve now, pay when you stay
15.97 mi from Otay Mesa
$167 nightly
The price is $194 total per night
$194 total
Jul 2 - Jul 3
Total with taxes and fees
Guests of Wyndham San Diego Bayside have access to an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 50.00 per night. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Pet friendly

Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
18.15 mi from Otay Mesa
$197 nightly
The price is $227 total per night
$227 total
Jul 1 - Jul 2
Total with taxes and fees
At Bay Club Hotel & Marina, guests enjoy a marina, an outdoor pool, and a gym. Self parking is available for USD 24 per night. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, tours or tickets, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place San Diego CA
Free Cancellation
Reserve now, pay when you stay
18.71 mi from Otay Mesa
$135 nightly
The price is $155 total per night
$155 total
Jun 30 - Jul 1
Total with taxes and fees
At Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 30 per night. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, tours or tickets, and securing valuables. Additional amenities include a hot tub, coffee/tea in a common area, and express check-out.

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
21.45 mi from Otay Mesa
$325 nightly
The price is $374 total per night
$374 total
Jun 30 - Jul 1
Total with taxes and fees
Paradise Point Resort & Spa features a marina, a full-service spa, and 5 outdoor pools. Self parking is available for USD 49 per night. The front desk has multilingual staff on hand 24/7 to help with tours or tickets, dry cleaning/laundry, and luggage storage. Other amenities at this beach resort include a gym, 5 hot tubs, and a sauna.
Pool
Hot Tub

Bahia Resort Hotel
998 W Mission Bay Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
21.65 mi from Otay Mesa
$353 nightly
The price is $406 total per night
$406 total
Jul 12 - Jul 13
Total with taxes and fees
At Bahia Resort Hotel, guests enjoy features like an outdoor pool, a gym, and outdoor tennis courts. If you drive, self parking is USD 48.00 per day, and there's also limo/town car service. The front desk has multilingual staff that can help with concierge services, securing valuables, and luggage storage. Other amenities at this beach resort include a hot tub, conference space, and a business center.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa hotels essential information
Accommodation | 4,914 hotels |
|---|---|
Lowest Price | $138 |
Highest Price | $406 |
Popular hotels | Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, Wyndham San Diego Bayside, Paradise Point Resort & Spa, Hard Rock Hotel San Diego, Bay Club Hotel & Marina, The DEXTRO Little Italy, BW Premier Collection, Bahia Resort Hotel, Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , Manchester Grand Hyatt San Diego |
Recent Reviews

Hard Rock Hotel San Diego
4/5 Good
"Very clean, friendly staff walkable to Petco park center of Gaslamp bars and restaurants. The only complaint was parking if you are doing valet at hard rock long line and pricey."
A verified traveler stayed at Hard Rock Hotel San Diego
Posted less than an hour ago
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