Business Hotels in Southwest Missouri, MO
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Featured Southwest Missouri Business Hotels

Hotel Vandivort
305 E. Walnut Springfield MO
Free Cancellation
Reserve now, pay when you stay
$159 nightly
The price is $182 total per night
$182 total
Dec 23 - Dec 24
Total with taxes and fees
At Hotel Vandivort, guests have access to a 24-hour gym, free WiFi in public areas, and meeting rooms. Valet parking is offered for USD 19 per night. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and luggage storage. Additional amenities include conference space, a terrace, and wedding services.
Pet friendly
Free WiFi

University Plaza Hotel and Convention Center Springfield
333 S John Q Hammons Pkwy Springfield MO
Free Cancellation
Reserve now, pay when you stay
$101 nightly
The price is $114 total per night
$114 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
University Plaza Hotel and Convention Center Springfield features an indoor pool, a 24-hour gym, and a conference center. Self parking is offered for USD 10 per day. The 24-hour front desk has staff standing by to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and a computer station.
Pool
Pet friendly

La Quinta Inn & Suites by Wyndham Joplin
3320 S Range Line Rd Joplin MO
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $101 total per night
$101 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Joplin features an indoor pool, an outdoor pool, and a gym. There's free parking, as well as a free airport shuttle (available 24 hours). Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

MainStay Suites Springfield South - Battlefield Rd
1550 E Raynell Pl Springfield MO
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $96 total per night
$96 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Guests of MainStay Suites Springfield South - Battlefield Rd enjoy access to free WiFi in public areas, a 24-hour business center, and coffee in a common area. There's free parking if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include express check-in, express check-out, and a terrace.
Kitchen
Pet friendly

Lamplighter Inn & Suites - North
2820 N. Glenstone Avenue Springfield MO
At Lamplighter Inn & Suites - North, guests have access to free WiFi in public areas, a hot tub, and laundry facilities. A stay here includes free parking. Front-desk staff are standing by 24/7 to assist with any requests. This hotel also has a vending machine.
Hot Tub
Pet friendly

Sleep Inn Springfield South I60 near Medical District
233 E Camino Alto Springfield MO
Free Cancellation
$89 nightly
The price is $101 total per night
$101 total
Dec 21 - Dec 22
Total with taxes and fees
At Sleep Inn Springfield South I60 near Medical District, guests have access to an indoor pool, free WiFi in public areas, and a hot tub. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include meeting rooms, coffee/tea in a common area, and express check-out.
Pool
Hot Tub

West Plains Motel
505 Porter Wagoner Blvd West Plains MO
Renovated in 2017, West Plains Motel offers free WiFi in public areas, coffee in a common area, and express check-in. If you drive, put free parking to good use. Helpful staff is there to provide front-desk service during limited hours, as well as offer insight about the area. Additional amenities include express check-out, laundry facilities, and a vending machine.
Pet friendly
Parking included

The Bradford Hotel, an Ascend Collection Hotel
1260 E Independence St Springfield MO
Free Cancellation
$79 nightly
The price is $90 total per night
$90 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At The Bradford Hotel, an Ascend Collection Hotel, guests have access to free WiFi in public areas, a seasonal outdoor pool, and laundry facilities. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a vending machine and a TV in a common area.
Pool
Breakfast included

Homewood Suites by Hilton Joplin
2642 East 32nd Street Joplin MO
Free Cancellation
Reserve now, pay when you stay
$127 nightly
The price is $144 total per night
$144 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Homewood Suites by Hilton Joplin have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and tours or tickets. Additional amenities include a hot tub, a business center, and coffee/tea in a common area.
Pool
Hot Tub

Oasis Hotel & Conv. Center, an Ascend Collection Hotel
2546 North Glenstone Avenue Springfield MO
Free Cancellation
$93 nightly
The price is $105 total per night
$105 total
Dec 16 - Dec 17
Total with taxes and fees
Guests of Oasis Hotel & Conv. Center, an Ascend Collection Hotel have access to an outdoor pool, a gym, and free WiFi in public areas. There's free parking, as well as a free airport shuttle (available on request). The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls and an off-leash area. Additional amenities include a conference center, express check-in, and express check-out.
Pool
Breakfast included

Honeysuckle Inn & Conference Center
3598 Shepherd Of The Hills Expy Branson MO
Guests of Honeysuckle Inn & Conference Center enjoy an outdoor pool, free WiFi in public areas, and meeting rooms. You can take advantage of free parking, along with an area shuttle for a fee. The 24-hour front desk has staff standing by to help with tours/tickets and securing valuables. Additional amenities include a conference center, coffee/tea in a common area, and express check-out.
Pool
Breakfast included

Comfort Inn South - Springfield
3776 S Glenstone Avenue Springfield MO
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $105 total per night
$105 total
Dec 21 - Dec 22
Total with taxes and fees
At Comfort Inn South - Springfield, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub

Angel Inn Central
2350 Green Mountain Dr Branson MO
Free Cancellation
Reserve now, pay when you stay
$54 nightly
The price is $61 total per night
$61 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
Angel Inn Central offers an indoor pool, free WiFi in public areas, and a hot tub. If you decide to drive, there's free parking. Front-desk staff can help with tours or tickets, and provide local restaurant recommendations. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a computer station.
Pool
Hot Tub

Ye Old English Inn
24 Downing Street Hollister MO
$110 nightly
The price is $125 total per night
$125 total
Dec 11 - Dec 12
Total with taxes and fees
Ye Old English Inn features a nightclub, free WiFi in public areas, and a meeting room. Front-desk staff can help with tours or tickets, and provide local restaurant recommendations. Additional amenities include a terrace, a fireplace in the lobby, and a garden.
Free WiFi
Restaurant

Country Inn & Suites by Radisson, Nevada, MO
2520 East Austin Boulevard Nevada MO
Free Cancellation
$91 nightly
The price is $102 total per night
$102 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At Country Inn & Suites by Radisson, Nevada, MO, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a library.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Southwest Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southwest Missouri hotels essential information
Accommodation | 8,827 hotels |
|---|---|
Lowest Price | $61 |
Highest Price | $182 |
Popular hotels | Hotel Vandivort, University Plaza Hotel and Convention Center Springfield, La Quinta Inn & Suites by Wyndham Joplin, MainStay Suites Springfield South - Battlefield Rd, Lamplighter Inn & Suites - North, Sleep Inn Springfield South I60 near Medical District, West Plains Motel, The Bradford Hotel, an Ascend Collection Hotel, Homewood Suites by Hilton Joplin, Oasis Hotel & Conv. Center, an Ascend Collection Hotel, Honeysuckle Inn & Conference Center, Comfort Inn South - Springfield, Angel Inn Central, Ye Old English Inn, Country Inn & Suites by Radisson, Nevada, MO |
Recent Business Hotels Reviews

The Stone Castle Hotel & Conference Center
5/5 Excellent
"We stay here a lot! We really like the facility, the price is awesome for the value. Its always clean, the staff is nice, beds are decent, they have two hot tubs and two pools so never too busy. The breakfast has a lot of choices. I love that they have fresh made oatmeal. "
A verified traveler stayed at The Stone Castle Hotel & Conference Center
Posted 1 day ago
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