Hotels near Mayo Clinic Florida
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Check prices close to Mayo Clinic Florida for tomorrow night, Feb 28 - Mar 1Featured Hotels near Mayo Clinic Florida

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
14390 Mayo Boulevard Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.23 mi from Mayo Clinic Florida
$179 nightly
The price is $203 total per night
$203 total
Feb 28 - Mar 1
Total with taxes and fees
At Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, conference space, and a business center.
Pool
Parking included

Hilton Jacksonville At Mayo Clinic
4745 Transformation Way Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.48 mi from Mayo Clinic Florida
$196 nightly
The price is $222 total per night
$222 total
Mar 21 - Mar 22
Total with taxes and fees
Built in 2025, the brand new Hilton Jacksonville At Mayo Clinic offers an outdoor pool, a gym, and free WiFi in public areas. There's free parking and a free area shuttle. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and concierge services. Other amenities at this luxury hotel include meeting rooms, conference space, and express check-out.
Pool
Parking included

New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach
Jacksonville FL
0.58 mi from Mayo Clinic Florida
$358 nightly
The price is $403 total per night
$403 total
Feb 28 - Mar 1
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.
Kitchen
Washer

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH Jacksonville FL
0.67 mi from Mayo Clinic Florida
$193 nightly
The price is $219 total per night
$219 total
Mar 5 - Mar 6
Total with taxes and fees
At Residence Inn By Marriott Jacksonville - Mayo Clinic Area, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk has multilingual staff on hand 24/7 to help with luggage storage, concierge services, and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
Jacksonville FL
0.75 mi from Mayo Clinic Florida
At this vacation home, guests have access to an arcade/game room, laundry facilities, and barbecue grills. This family-friendly vacation home also has a garden.
Kitchen
Washer

Comfy Mayo Retreat; Heated Pool, Close to Beach
Jacksonville Beach FL
0.98 mi from Mayo Clinic Florida
This vacation home offers a water park, an arcade/game room, and laundry facilities. This family-friendly vacation home also has barbecue grills.
Pool
Kitchen

Quiet Coastal Home w/ Patio Near Beaches
Jacksonville FL
1.39 mi from Mayo Clinic Florida
This vacation home is a smoke-free vacation home.
Washer
Dryer

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
4791 Windsor Commons Ct Jacksonville FL
Free Cancellation
1.64 mi from Mayo Clinic Florida
$115 nightly
The price is $131 total per night
$131 total
Mar 27 - Mar 28
Total with taxes and fees
Guests of Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG have access to an outdoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with an area shuttle. Multilingual staff at the 24-hour front desk can assist with securing valuables, dry cleaning/laundry, and luggage storage. Other amenities at this golf hotel include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Margaritaville Jacksonville Beach
715 1st St N Jacksonville Beach FL
Free Cancellation
Reserve now, pay when you stay
3.65 mi from Mayo Clinic Florida
$169 nightly
The price is $192 total per night
$192 total
Mar 1 - Mar 2
Total with taxes and fees
Margaritaville Jacksonville Beach features karaoke, an outdoor pool, and a gym. Valet parking is available for USD 27.00 per day. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this beach hotel include free WiFi in public areas, meeting rooms, and a 24-hour business center.
Pool
Free WiFi
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mayo Clinic Florida hotels essential information
Accommodation | 1,905 hotels |
|---|---|
Lowest Price | $131 |
Highest Price | $403 |
Popular hotels | Hilton Jacksonville At Mayo Clinic, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Margaritaville Jacksonville Beach, New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach, Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard, Comfy Mayo Retreat; Heated Pool, Close to Beach, Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG, Quiet Coastal Home w/ Patio Near Beaches |
Recent Reviews

New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach
5/5 Excellent
"The house was perfect for our stay, close to Mayo Clinic and very comfortable. Was decorated nice and was very clean. Would highly recommend."
A verified traveler stayed at New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach
Posted 2 days ago
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