Hotels near Mayo Clinic Florida
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Check prices close to Mayo Clinic Florida for tomorrow night, Jun 12 - Jun 13Featured Hotels near Mayo Clinic Florida

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
14390 Mayo Boulevard Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.23 mi from Mayo Clinic Florida
$152 nightly
The price is $173 total per night
$173 total
Jun 20 - Jun 21
Total with taxes and fees
At Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, conference space, and a business center.
Pool
Parking included

Hilton Jacksonville At Mayo Clinic
4745 Transformation Way Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.48 mi from Mayo Clinic Florida
$163 nightly
The price is $185 total per night
$185 total
Jun 27 - Jun 28
Total with taxes and fees
Built in 2025, the brand new Hilton Jacksonville At Mayo Clinic offers an outdoor pool, a gym, and free WiFi in public areas. If you drive, self parking is USD 12.00 per night, and there's also a free area shuttle. The 24-hour front desk has staff standing by to help with concierge services, dry cleaning/laundry, and luggage storage. Other amenities at this luxury hotel include meeting rooms, conference space, and express check-out.
Pool
Free WiFi

Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
Jacksonville FL
0.55 mi from Mayo Clinic Florida
At this vacation home, guests have access to a gym, laundry facilities, and a garden.
Kitchen
Washer

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.67 mi from Mayo Clinic Florida
$163 nightly
The price is $185 total per night
$185 total
Jun 19 - Jun 20
Total with taxes and fees
At Residence Inn By Marriott Jacksonville - Mayo Clinic Area, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
Jacksonville FL
0.75 mi from Mayo Clinic Florida
At this vacation home, guests have access to an arcade/game room, laundry facilities, and a garden. This family-friendly vacation home also has barbecue grills.
Kitchen
Washer

Private Pool Getaway • 5min Beach • Sleeps 9
Jacksonville FL
0.78 mi from Mayo Clinic Florida
$480 nightly
The price is $537 total per night
$537 total
Jun 15 - Jun 16
Total with taxes and fees
At this vacation home, guests have access to an outdoor pool, laundry facilities, and a garden.
Pool
Kitchen

Beautiful 3 bedroom, 2 bathroom Beach Bungalow in Jacksonville Beach!
Jacksonville FL
1.34 mi from Mayo Clinic Florida
$360 nightly
The price is $403 total per night
$403 total
Jun 18 - Jun 19
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has a garden.
Kitchen
Washer

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
4791 Windsor Commons Ct Jacksonville FL
Free Cancellation
1.64 mi from Mayo Clinic Florida
$116 nightly
The price is $132 total per night
$132 total
Jun 21 - Jun 22
Total with taxes and fees
Guests of Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG have access to an outdoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with an area shuttle. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, securing valuables, and luggage storage. Other amenities at this golf hotel include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Margaritaville Jacksonville Beach
715 1st St N Jacksonville Beach FL
Free Cancellation
Reserve now, pay when you stay
3.65 mi from Mayo Clinic Florida
$167 nightly
The price is $190 total per night
$190 total
Jun 14 - Jun 15
Total with taxes and fees
At Margaritaville Jacksonville Beach, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. Valet parking is available for USD 27.00 per day. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Other amenities at this beach hotel include meeting rooms, a 24-hour business center, and laundry facilities.
Pool
Free WiFi
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mayo Clinic Florida hotels essential information
Accommodation | 1,885 hotels |
|---|---|
Lowest Price | $132 |
Highest Price | $537 |
Popular hotels | Hilton Jacksonville At Mayo Clinic, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Margaritaville Jacksonville Beach, Light Grey Getaway under 2 miles to mayo, 4 miles to the beach, Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard, Private Pool Getaway • 5min Beach • Sleeps 9, Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG, Beautiful 3 bedroom, 2 bathroom Beach Bungalow in Jacksonville Beach! |
Recent Reviews

Margaritaville Jacksonville Beach
5/5 Excellent
"Great room and very convenient location"
A verified traveler stayed at Margaritaville Jacksonville Beach
Posted 4 hours ago
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