Book 5 Star Hotels in Otay Mesa
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Featured Otay Mesa 5 Stars Hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct, San Diego, CA
Free Cancellation
1.96 mi from Otay Mesa
$139 nightly
The price is $158 total per night
$158 total
Aug 10 - Aug 11
Total includes taxes and fees
Guests staying at Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG enjoy an outdoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24/7 to help with tours or tickets, luggage storage, and securing valuables. Additional amenities include a business center, a meeting room, and express check-in.
Pool
Breakfast included
Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
14.72 mi from Otay Mesa
$243 nightly
The price is $281 total per night
$281 total
Aug 18 - Aug 19
Total includes taxes and fees
Hilton San Diego Bayfront features a full-service spa, an outdoor pool, and a children's pool. Parking is available for USD 55.00 per night (USD 75.00 per night for valet parking), and there's also limo/town car service. Multilingual staff at the 24-hour front desk can assist with concierge services, luggage storage, and dry cleaning/laundry. Other amenities at this spa hotel include a gym, a sauna, and free WiFi in public areas.
Pool
Hot Tub
Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.21 mi from Otay Mesa
$272 nightly
The price is $315 total per night
$315 total
Aug 17 - Aug 18
Total includes taxes and fees
Marriott Marquis San Diego Marina features a marina, a full-service spa, and 2 outdoor pools. Valet parking is available for USD 75 per day. The 24-hour front desk has multilingual staff ready to assist with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this spa hotel include a children's pool, a 24-hour gym, and a sauna.
Pool
Hot Tub
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.38 mi from Otay Mesa
$244 nightly
The price is $283 total per night
$283 total
Jul 28 - Jul 29
Total includes taxes and fees
Guests staying at Manchester Grand Hyatt San Diego enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 65 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, tours or tickets, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub
The Dextro Hotel, BW Premier Collection
1617 1st Avenue, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.76 mi from Otay Mesa
$135 nightly
The price is $157 total per night
$157 total
Aug 3 - Aug 4
Total includes taxes and fees
Guests of Dextro, Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 35.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and tours/tickets. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free WiFi
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
15.97 mi from Otay Mesa
$169 nightly
The price is $195 total per night
$195 total
Jul 28 - Jul 29
Total includes taxes and fees
Guests of Wyndham San Diego Bayside have access to an outdoor pool, a gym, and WiFi in public areas. Parking is USD 50.00 per night (USD 60 per night for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle at scheduled times. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Free airport shuttle
Handlery Hotel
950 Hotel Cir N, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.06 mi from Otay Mesa
$111 nightly
The price is $128 total per night
$128 total
Aug 10 - Aug 11
Total includes taxes and fees
At Handlery Hotel, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 24 per night. The 24-hour front desk has multilingual staff ready to assist with concierge services, luggage storage, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
18.71 mi from Otay Mesa
$161 nightly
The price is $185 total per night
$185 total
Aug 24 - Aug 25
Total includes taxes and fees
At Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 19 per night. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, tours or tickets, and securing valuables. Additional amenities include a hot tub, coffee/tea in a common area, and express check-out.
Pool
Hot Tub
The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
20.96 mi from Otay Mesa
$166 nightly
The price is $190 total per night
$190 total
Aug 25 - Aug 26
Total includes taxes and fees
Guests of The Dana on Mission Bay have access to a marina, 2 outdoor pools, and a gym. Self parking is available for USD 35 per night. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include 2 hot tubs, free WiFi in public areas, and a conference center.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best 5 star hotels in Otay Mesa
Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Otay Mesa. After all, treating yourself to the finer things is what vacations are about.
What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Otay Mesa hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.
What amenities can I expect at a 5 star hotel?
Otay Mesa 5 star hotels and resorts typically offer luxury amenities such as:
- Gourmet restaurant
- Full-service fitness center with pool
- Luxury spa
- Welcome gifts upon arrival
- Top-of-the-line beds and linens
- Designer personal care products
- Premium cable, free Wi-Fi and device docking stations
How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Otay Mesa with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place:
- Search hotels by price, ranging from $128 to $315
- Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
- Choose from 4,638 5 star hotels in Otay Mesa!
Otay Mesa hotels essential information
Accommodation | 4,638 hotels |
|---|---|
Lowest Price | $128 |
Highest Price | $315 |
Popular hotels | Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, Handlery Hotel, Wyndham San Diego Bayside, Manchester Grand Hyatt San Diego, The Dana on Mission Bay, Marriott Marquis San Diego Marina, The Dextro Hotel, BW Premier Collection, Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , Hilton San Diego Bayfront |
Recent Reviews
The Dana on Mission Bay
5/5 Excellent
"Very clean, everyday the staff would come to clean the room. Ambience very calm suitable for family. "
A verified traveler stayed at The Dana on Mission Bay
Posted 23 hours ago
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