Cheap flights from SAT to FLO (San Antonio Intl. to Florence Regional)
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Hotel Ideas near Florence Regional
Airport Hotels near Florence Regional
Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
$122 nightly
The price is $137 total per night from Apr 26 to Apr 27
$137 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,005 reviews)
Clean very quite I had a wonderful stay
Reviewed on Apr 11, 2026
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Apr 26 to Apr 27
$146 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (625 reviews)
I called ahead to request a pack and play for our small child in our suite for when we arrived since it was going to be late, they said no problem. We asked the front desk if the pack and play is in the room already, they said yes. We got in the room.. and the pack and play was not there. The TV ...
Reviewed on Apr 4, 2026
Rodeway Inn Florence Downtown
415 S. IRBY ST Florence SC
$57 nightly
The price is $63 total per night from May 10 to May 11
$63 total
May 10 - May 11
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Drs Bruce and Lee Foundation Library and Florence ...
4.6/10 (4 reviews)
Looks like the owners are doing a lot of work on the property however, cleanliness is doable but not done. Our room was supposed to have 2 beds in it but the first room we got looked like someone was still in it. Unmade bed, clothes on chair and a huge fan in the middle of the room. Second room, ...
Reviewed on Mar 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Florence
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
$67 nightly
The price is $75 total per night from Apr 26 to Apr 27
$75 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,627 reviews)
Perfect for an affordable overnight stay. Remodeled in recent years, so clean and comfortable. Staff was friendly and decent breakfast in the am.
Reviewed on Apr 11, 2026
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
$89 nightly
The price is $100 total per night from Apr 26 to Apr 27
$100 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,258 reviews)
Breakfast wasn’t fresh. Shower wasn’t clean
Reviewed on Apr 12, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
$99 nightly
The price is $111 total per night from May 3 to May 4
$111 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,262 reviews)
Safe area, clean hotel. Coffee empty. No water in AM
Reviewed on Apr 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Florence Hotels
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from May 3 to May 4
$63 total
May 3 - May 4
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,004 reviews)
It does the job. Clean bed and bathroom.
Reviewed on Apr 10, 2026
Budget Inn Timmonsville
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Apr 13 to Apr 14
$68 total
Apr 13 - Apr 14
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (335 reviews)
Clean room. Nothing bad and nothing special. It was a good peaceful stay.
Reviewed on Apr 2, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Apr 19 to Apr 20
$74 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,006 reviews)
Honestly the breakfast was a joke the only thing they really had was waffles and fruit. My room was on the back side of the hotel and upstairs there was a bunch of guys that were partying every night the whole week that I was there. The room was dirty room service never came by I actually had to ...
Reviewed on Apr 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Florence
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
$129 nightly
The price is $144 total per night from Apr 26 to Apr 27
$144 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,007 reviews)
We love staying here! Great staff and huge rooms- super conveniently located for the hockey crowd; can walk to the arena :)
Reviewed on Apr 11, 2026
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$93 nightly
The price is $104 total per night from May 3 to May 4
$104 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (66 reviews)
The room was clean and bed very comfortable. Staff were pleasant and helpful.
Reviewed on Apr 11, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Apr 19 to Apr 20
$74 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,006 reviews)
Honestly the breakfast was a joke the only thing they really had was waffles and fruit. My room was on the back side of the hotel and upstairs there was a bunch of guys that were partying every night the whole week that I was there. The room was dirty room service never came by I actually had to ...
Reviewed on Apr 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
SAT to FLO Route Info
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SAT Address & GPS
Address:
9800 Airport Boulevard
San Antonio TX, 78216
United States
IATA Code:
SAT
Longitude:
-98.472643
Latitude:
29.524937
Time Zone:
America/Chicago
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York
Other Flights from San Antonio Intl. Airport (SAT)
Other Flights to Florence Regional Airport (FLO)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.