Cheap flights from SAT to FLO (San Antonio Intl. to Florence Regional)
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Cheap Flights from SAT to FLO starting at $445 One Way, $551 Round Trip
Prices starting at $551 for return flights and $445 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
SAT
San Antonio
FLO
Florence
$551 Roundtrip, found 1 day ago
$551
Roundtrip
found 1 day ago
SAT
San Antonio
FLO
Florence
$588 Roundtrip, found 1 day ago
$588
Roundtrip
found 1 day ago
SAT
San Antonio
FLO
Florence
$623 Roundtrip, found 1 day ago
$623
Roundtrip
found 1 day ago
SAT
San Antonio
FLO
Florence
$626 Roundtrip, found 1 day ago
$626
Roundtrip
found 1 day ago
SAT
San Antonio
FLO
Florence
$634 Roundtrip, found 1 day ago
$634
Roundtrip
found 1 day ago
Hotel Ideas near Florence Regional
Airport Hotels near Florence Regional
Hyatt Place Florence Downtown
100 East Evans Street Florence Florence SC
$122 nightly
The price is $137 total per night from Apr 12 to Apr 13
$137 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
9/10 Wonderful! (1,006 reviews)
Nice clean room for family of 4
Reviewed on Apr 4, 2026
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Apr 26 to Apr 27
$146 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (625 reviews)
I called ahead to request a pack and play for our small child in our suite for when we arrived since it was going to be late, they said no problem. We asked the front desk if the pack and play is in the room already, they said yes. We got in the room.. and the pack and play was not there. The TV ...
Reviewed on Apr 4, 2026
Rodeway Inn Florence Downtown
415 S. IRBY ST Florence SC
$56 nightly
The price is $63 total per night from Apr 5 to Apr 6
$63 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Drs Bruce and Lee Foundation Library and Florence ...
4.6/10 (4 reviews)
Looks like the owners are doing a lot of work on the property however, cleanliness is doable but not done. Our room was supposed to have 2 beds in it but the first room we got looked like someone was still in it. Unmade bed, clothes on chair and a huge fan in the middle of the room. Second room, ...
Reviewed on Mar 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Florence
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
$67 nightly
The price is $75 total per night from Apr 5 to Apr 6
$75 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,613 reviews)
Breakfast was ok. Parking was available and the overall stay was good
Reviewed on Apr 4, 2026
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
$89 nightly
The price is $100 total per night from Apr 26 to Apr 27
$100 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,235 reviews)
Great stay!
Reviewed on Apr 4, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
$99 nightly
The price is $111 total per night from Apr 26 to Apr 27
$111 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,242 reviews)
Breakfast was late
Reviewed on Apr 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Florence Hotels
Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from May 3 to May 4
$63 total
May 3 - May 4
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,001 reviews)
Lots of dining opportunities!
Reviewed on Apr 2, 2026
Budget Inn Timmonsville
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Apr 5 to Apr 6
$68 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (332 reviews)
Clean room. Nothing bad and nothing special. It was a good peaceful stay.
Reviewed on Apr 2, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Apr 14 to Apr 15
$74 total
Apr 14 - Apr 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,005 reviews)
Breakfast items are very limited. Parking is safe.
Reviewed on Apr 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Florence
Home2 Suites by Hilton Florence, SC
900 Woody Jones Blvd Florence SC
$130 nightly
The price is $146 total per night from May 5 to May 6
$146 total
May 5 - May 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
Breakfast was not good Run out of food at 9 am
Reviewed on Apr 3, 2026
Spark by Hilton Florence North I-95, SC
1739 Mandeville Rd Florence SC
$93 nightly
The price is $104 total per night from Apr 13 to Apr 14
$104 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (60 reviews)
Hotel was OK. Breakfast was slim. Very small selection, everything was fresh. Bed was comfy.
Reviewed on Mar 30, 2026
Days Inn by Wyndham Florence Near Civic Center
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Apr 14 to Apr 15
$74 total
Apr 14 - Apr 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,005 reviews)
Breakfast items are very limited. Parking is safe.
Reviewed on Apr 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
SAT to FLO Route Info
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Destination Airport | |
Number Of Airlines Serving | |
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Shortest Flight Departure Time | |
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SAT Address & GPS
Address:
9800 Airport Boulevard
San Antonio TX, 78216
United States
IATA Code:
SAT
Longitude:
-98.472643
Latitude:
29.524937
Time Zone:
America/Chicago
FLO Address & GPS
Address:
2100 Terminal Drive
Florence SC, 29501
United States
IATA Code:
FLO
Longitude:
-79.724444
Latitude:
34.188889
Time Zone:
America/New_York
Other Flights from San Antonio Intl. Airport (SAT)
Other Flights to Florence Regional Airport (FLO)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.